Nonlinear Multi-Objective Flux Balance Analysis of the Warburg Effect

1 code implementation • 23 Nov 2021 • Yi Zhang, Daniel Boley

To extend the applicability of the previous model and model the disparate cellular pathway preferences in different cell types, we built a Nonlinear Multi-Objective FBA (NLMOFBA) model by including three key objective terms (ATP production rate, lactate generation rate and ATP yield) into one objective function through linear scalarization.

A Prospective Observational Study to Investigate Performance of a Chest X-ray Artificial Intelligence Diagnostic Support Tool Across 12 U.S. Hospitals

no code implementations • 3 Jun 2021 • Ju Sun, Le Peng, Taihui Li, Dyah Adila, Zach Zaiman, Genevieve B. Melton, Nicholas Ingraham, Eric Murray, Daniel Boley, Sean Switzer, John L. Burns, Kun Huang, Tadashi Allen, Scott D. Steenburg, Judy Wawira Gichoya, Erich Kummerfeld, Christopher Tignanelli

Conclusions and Relevance: AI-based diagnostic tools may serve as an adjunct, but not replacement, for clinical decision support of COVID-19 diagnosis, which largely hinges on exposure history, signs, and symptoms.

COVID-19 Diagnosis Decision Making

Mining Novel Multivariate Relationships in Time Series Data Using Correlation Networks

1 code implementation • 6 Oct 2018 • Saurabh Agrawal, Michael Steinbach, Daniel Boley, Snigdhansu Chatterjee, Gowtham Atluri, Anh The Dang, Stefan Liess, Vipin Kumar

In many domains, there is significant interest in capturing novel relationships between time series that represent activities recorded at different nodes of a highly complex system.

Time Series Time Series Analysis