Search Results for author: Joseph H. Davis

Found 4 papers, 1 papers with code

Imaging structurally dynamic ribosomes with cryogenic electron microscopy

no code implementations30 Aug 2023 Samantha M. Webster, Mira B. May, Barrett M. Powell, Joseph H. Davis

Throughout the history of electron microscopy, ribosomes have served as an ideal subject for imaging and technological development, which in turn has driven our understanding of ribosomal biology.

Cryogenic Electron Tomography Electron Tomography +1

Exploring generative atomic models in cryo-EM reconstruction

no code implementations3 Jul 2021 Ellen D. Zhong, Adam Lerer, Joseph H. Davis, Bonnie Berger

Although reconstruction algorithms typically model the 3D volume as a generic function parameterized as a voxel array or neural network, the underlying atomic structure of the protein of interest places well-defined physical constraints on the reconstructed structure.

Protein Folding

CryoDRGN2: Ab Initio Neural Reconstruction of 3D Protein Structures From Real Cryo-EM Images

no code implementations ICCV 2021 Ellen D. Zhong, Adam Lerer, Joseph H. Davis, Bonnie Berger

In this work we describe cryoDRGN2, an ab initio reconstruction algorithm, which can jointly estimate image poses and learn a neural model of a distribution of 3D structures on real heterogeneous cryo-EM data.

Reconstructing continuous distributions of 3D protein structure from cryo-EM images

2 code implementations ICLR 2020 Ellen D. Zhong, Tristan Bepler, Joseph H. Davis, Bonnie Berger

Cryo-electron microscopy (cryo-EM) is a powerful technique for determining the structure of proteins and other macromolecular complexes at near-atomic resolution.

3D Volumetric Reconstruction Clustering +2

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