Search Results for author: Laetitia Papaxanthos

Found 5 papers, 1 papers with code

Conditional Generative Modeling for De Novo Hierarchical Multi-Label Functional Protein Design

no code implementations1 Jan 2021 Tim Kucera, Karsten Michael Borgwardt, Matteo Togninalli, Laetitia Papaxanthos

The availability of vast protein sequence information and rich functional annotations thereof has a large potential for protein design applications in biomedicine and synthetic biology.

Protein Design valid

Inferring Concept Hierarchies from Text Corpora via Hyperbolic Embeddings

no code implementations ACL 2019 Matt Le, Stephen Roller, Laetitia Papaxanthos, Douwe Kiela, Maximilian Nickel

Moreover -- and in contrast with other methods -- the hierarchical nature of hyperbolic space allows us to learn highly efficient representations and to improve the taxonomic consistency of the inferred hierarchies.

Finding significant combinations of features in the presence of categorical covariates

1 code implementation NeurIPS 2016 Laetitia Papaxanthos, Felipe Llinares-Lopez, Dean Bodenham, Karsten Borgwardt

In high-dimensional settings, where the number of features p is typically much larger than the number of samples n, methods which can systematically examine arbitrary combinations of features, a huge 2^p-dimensional space, have recently begun to be explored.

Searching for significant patterns in stratified data

no code implementations24 Aug 2015 Felipe Llinares-Lopez, Laetitia Papaxanthos, Dean Bodenham, Karsten Borgwardt

Significant pattern mining, the problem of finding itemsets that are significantly enriched in one class of objects, is statistically challenging, as the large space of candidate patterns leads to an enormous multiple testing problem.

Fast and Memory-Efficient Significant Pattern Mining via Permutation Testing

no code implementations15 Feb 2015 Felipe Llinares López, Mahito Sugiyama, Laetitia Papaxanthos, Karsten M. Borgwardt

Westfall-Young light opens the door to significant pattern mining on large datasets that previously led to prohibitive runtime or memory costs.

Two-sample testing

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