no code implementations • 1 Mar 2024 • Paul François, Victoria Mochulska
Proper vertebrae formation relies on a tissue-wide oscillator called the segmentation clock.
1 code implementation • 4 Dec 2023 • Nacer Eddine Boukacem, Allen Leary, Robin Thériault, Felix Gottlieb, Madhav Mani, Paul François
Focusing on the prototype learning dynamics of the internal memories we observe a strong resemblance to the canalized, or low-dimensional, dynamics of cells as they differentiate within a Waddingtonian landscape.
no code implementations • 10 Jul 2018 • Thomas J. Rademaker, Emmanuel Bengio, Paul François
We then apply a gradient-descent approach from machine learning to different cellular decision-making models, and we reveal the existence of two regimes characterized by the presence or absence of a critical point for the gradient.