no code implementations • 6 Mar 2024 • Elsa Lawrence, Adham El-Shazly, Srijit Seal, Chaitanya K Joshi, Pietro Liò, Shantanu Singh, Andreas Bender, Pietro Sormanni, Matthew Greenig
Modern life sciences research is increasingly relying on artificial intelligence approaches to model biological systems, primarily centered around the use of machine learning (ML) models.
1 code implementation • 25 Jan 2024 • Talip Ucar, Aubin Ramon, Dino Oglic, Rebecca Croasdale-Wood, Tom Diethe, Pietro Sormanni
We investigate the potential of patent data for improving the antibody humanness prediction using a multi-stage, multi-loss training process.
1 code implementation • 10 Oct 2023 • John D Boom, Matthew Greenig, Pietro Sormanni, Pietro Liò
We apply our framework to design antibody binding loop structures conditional on a target epitope and evaluate a variety of modelling choices in SGM-based protein design.
no code implementations • 12 Jun 2018 • Andreea Deac, Petar Veličković, Pietro Sormanni
Antibodies are a critical part of the immune system, having the function of directly neutralising or tagging undesirable objects (the antigens) for future destruction.