Search Results for author: Pietro Sormanni

Found 4 papers, 2 papers with code

Understanding Biology in the Age of Artificial Intelligence

no code implementations6 Mar 2024 Elsa Lawrence, Adham El-Shazly, Srijit Seal, Chaitanya K Joshi, Pietro Liò, Shantanu Singh, Andreas Bender, Pietro Sormanni, Matthew Greenig

Modern life sciences research is increasingly relying on artificial intelligence approaches to model biological systems, primarily centered around the use of machine learning (ML) models.

Protein Structure Prediction

Improving Antibody Humanness Prediction using Patent Data

1 code implementation25 Jan 2024 Talip Ucar, Aubin Ramon, Dino Oglic, Rebecca Croasdale-Wood, Tom Diethe, Pietro Sormanni

We investigate the potential of patent data for improving the antibody humanness prediction using a multi-stage, multi-loss training process.

Contrastive Learning Drug Discovery

Score-Based Generative Models for Designing Binding Peptide Backbones

1 code implementation10 Oct 2023 John D Boom, Matthew Greenig, Pietro Sormanni, Pietro Liò

We apply our framework to design antibody binding loop structures conditional on a target epitope and evaluate a variety of modelling choices in SGM-based protein design.

Protein Design

Attentive cross-modal paratope prediction

no code implementations12 Jun 2018 Andreea Deac, Petar Veličković, Pietro Sormanni

Antibodies are a critical part of the immune system, having the function of directly neutralising or tagging undesirable objects (the antigens) for future destruction.

Computational Efficiency

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