no code implementations • 30 Oct 2023 • Sabrina Schönfeld, Laura Scarabosio, Alican Ozkan, Marissa Nichole Rylander, Christina Kuttler
Using a novel modeling approach based on the so-called environmental stress level (ESL), we develop a mathematical model to describe systematically the collective influence of oxygen concentration and stiffness of the extracellular matrix on the response of tumor cells to a combined chemotherapeutic treatment.
