Search Results for author: Susan Holmes

Found 9 papers, 4 papers with code

Geomstats: A Python Package for Riemannian Geometry in Machine Learning

1 code implementation ICLR 2019 Nina Miolane, Alice Le Brigant, Johan Mathe, Benjamin Hou, Nicolas Guigui, Yann Thanwerdas, Stefan Heyder, Olivier Peltre, Niklas Koep, Hadi Zaatiti, Hatem Hajri, Yann Cabanes, Thomas Gerald, Paul Chauchat, Christian Shewmake, Bernhard Kainz, Claire Donnat, Susan Holmes, Xavier Pennec

We introduce Geomstats, an open-source Python toolbox for computations and statistics on nonlinear manifolds, such as hyperbolic spaces, spaces of symmetric positive definite matrices, Lie groups of transformations, and many more.

BIG-bench Machine Learning Clustering +2

Estimation of Orientation and Camera Parameters from Cryo-Electron Microscopy Images with Variational Autoencoders and Generative Adversarial Networks

no code implementations19 Nov 2019 Nina Miolane, Frédéric Poitevin, Yee-Ting Li, Susan Holmes

As such, it opens the door to geometric approaches for unsupervised estimations of orientations and camera parameters, making possible fast cryo-EM biomolecule reconstruction.

Convex Hierarchical Clustering for Graph-Structured Data

no code implementations8 Nov 2019 Claire Donnat, Susan Holmes

Convex clustering is a recent stable alternative to hierarchical clustering.

Clustering

Uncertainty Quantification in Multivariate Mixed Models for Mass Cytometry Data

1 code implementation19 Mar 2019 Christof Seiler, Lisa M. Kronstad, Laura J. Simpson, Mathieu Le Gars, Elena Vendrame, Catherine A. Blish, Susan Holmes

In this article, our aim is to exhibit the use of statistical analyses on the raw, uncompressed data thus improving replicability, and exposing multivariate patterns and their associated uncertainty profiles.

Applications

Template shape estimation: correcting an asymptotic bias

no code implementations6 Sep 2016 Nina Miolane, Susan Holmes, Xavier Pennec

We use tools from geometric statistics to analyze the usual estimation procedure of a template shape.

Positive Curvature and Hamiltonian Monte Carlo

no code implementations NeurIPS 2014 Christof Seiler, Simon Rubinstein-Salzedo, Susan Holmes

The Jacobi metric introduced in mathematical physics can be used to analyze Hamiltonian Monte Carlo (HMC).

Curvature and Concentration of Hamiltonian Monte Carlo in High Dimensions

1 code implementation4 Jul 2014 Susan Holmes, Simon Rubinstein-Salzedo, Christof Seiler

In this article, we analyze Hamiltonian Monte Carlo (HMC) by placing it in the setting of Riemannian geometry using the Jacobi metric, so that each step corresponds to a geodesic on a suitable Riemannian manifold.

Probability Differential Geometry Statistics Theory Statistics Theory

Waste Not, Want Not: Why Rarefying Microbiome Data is Inadmissible

1 code implementation1 Oct 2013 Paul J. McMurdie, Susan Holmes

We use statistical theory, extensive simulations, and empirical data to show that variance stabilizing normalization using a mixture model like the negative binomial is appropriate for microbiome count data.

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