1 code implementation • 29 Dec 2023 • Ning Dai, Wei Yu Tang, Tianshuo Zhou, David H. Mathews, Liang Huang
We then use gradient descent-based optimization methods to improve the extended objective function, and the distribution will gradually shrink towards a one-hot sequence (i. e., a single sequence).
1 code implementation • 14 Nov 2023 • Tianshuo Zhou, Wei Yu Tang, David H. Mathews, Liang Huang
RNA design is the search for a sequence or set of sequences that will fold into predefined structures, also known as the inverse problem of RNA folding.