The Brain Tumor Segmentation (BraTS) Challenge 2023: Focus on Pediatrics (CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs)

26 May 2023 · Anahita Fathi Kazerooni, Nastaran Khalili, Xinyang Liu, Debanjan Haldar, Zhifan Jiang, Syed Muhammed Anwar, Jake Albrecht, Maruf Adewole, Udunna Anazodo, Hannah Anderson, Sina Bagheri, Ujjwal Baid, Timothy Bergquist, Austin J. Borja, Evan Calabrese, Verena Chung, Gian-Marco Conte, Farouk Dako, James Eddy, Ivan Ezhov, Ariana Familiar, Keyvan Farahani, Shuvanjan Haldar, Juan Eugenio Iglesias, Anastasia Janas, Elaine Johansen, Blaise V Jones, Florian Kofler, Dominic LaBella, Hollie Anne Lai, Koen van Leemput, Hongwei Bran Li, Nazanin Maleki, Aaron S McAllister, Zeke Meier, Bjoern Menze, Ahmed W Moawad, Khanak K Nandolia, Julija Pavaine, Marie Piraud, Tina Poussaint, Sanjay P Prabhu, Zachary Reitman, Andres Rodriguez, Jeffrey D Rudie, Mariana Sanchez-Montano, Ibraheem Salman Shaikh, Lubdha M. Shah, Nakul Sheth, Russel Taki Shinohara, Wenxin Tu, Karthik Viswanathan, Chunhao Wang, Jeffrey B Ware, Benedikt Wiestler, Walter Wiggins, Anna Zapaishchykova, Mariam Aboian, Miriam Bornhorst, Peter de Blank, Michelle Deutsch, Maryam Fouladi, Lindsey Hoffman, Benjamin Kann, Margot Lazow, Leonie Mikael, Ali Nabavizadeh, Roger Packer, Adam Resnick, Brian Rood, Arastoo Vossough, Spyridon Bakas, Marius George Linguraru ·

Pediatric tumors of the central nervous system are the most common cause of cancer-related death in children. The five-year survival rate for high-grade gliomas in children is less than 20\%. Due to their rarity, the diagnosis of these entities is often delayed, their treatment is mainly based on historic treatment concepts, and clinical trials require multi-institutional collaborations. The MICCAI Brain Tumor Segmentation (BraTS) Challenge is a landmark community benchmark event with a successful history of 12 years of resource creation for the segmentation and analysis of adult glioma. Here we present the CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs 2023 challenge, which represents the first BraTS challenge focused on pediatric brain tumors with data acquired across multiple international consortia dedicated to pediatric neuro-oncology and clinical trials. The BraTS-PEDs 2023 challenge focuses on benchmarking the development of volumentric segmentation algorithms for pediatric brain glioma through standardized quantitative performance evaluation metrics utilized across the BraTS 2023 cluster of challenges. Models gaining knowledge from the BraTS-PEDs multi-parametric structural MRI (mpMRI) training data will be evaluated on separate validation and unseen test mpMRI dataof high-grade pediatric glioma. The CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs 2023 challenge brings together clinicians and AI/imaging scientists to lead to faster development of automated segmentation techniques that could benefit clinical trials, and ultimately the care of children with brain tumors.

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