The Brain Tumor Segmentation (BraTS) Challenge 2023: Glioma Segmentation in Sub-Saharan Africa Patient Population (BraTS-Africa)

30 May 2023 · Maruf Adewole, Jeffrey D. Rudie, Anu Gbadamosi, Oluyemisi Toyobo, Confidence Raymond, Dong Zhang, Olubukola Omidiji, Rachel Akinola, Mohammad Abba Suwaid, Adaobi Emegoakor, Nancy Ojo, Kenneth Aguh, Chinasa Kalaiwo, Gabriel Babatunde, Afolabi Ogunleye, Yewande Gbadamosi, Kator Iorpagher, Evan Calabrese, Mariam Aboian, Marius Linguraru, Jake Albrecht, Benedikt Wiestler, Florian Kofler, Anastasia Janas, Dominic LaBella, Anahita Fathi Kzerooni, Hongwei Bran Li, Juan Eugenio Iglesias, Keyvan Farahani, James Eddy, Timothy Bergquist, Verena Chung, Russell Takeshi Shinohara, Walter Wiggins, Zachary Reitman, Chunhao Wang, Xinyang Liu, Zhifan Jiang, Ariana Familiar, Koen van Leemput, Christina Bukas, Maire Piraud, Gian-Marco Conte, Elaine Johansson, Zeke Meier, Bjoern H Menze, Ujjwal Baid, Spyridon Bakas, Farouk Dako, Abiodun Fatade, Udunna C Anazodo ·

Gliomas are the most common type of primary brain tumors. Although gliomas are relatively rare, they are among the deadliest types of cancer, with a survival rate of less than 2 years after diagnosis. Gliomas are challenging to diagnose, hard to treat and inherently resistant to conventional therapy. Years of extensive research to improve diagnosis and treatment of gliomas have decreased mortality rates across the Global North, while chances of survival among individuals in low- and middle-income countries (LMICs) remain unchanged and are significantly worse in Sub-Saharan Africa (SSA) populations. Long-term survival with glioma is associated with the identification of appropriate pathological features on brain MRI and confirmation by histopathology. Since 2012, the Brain Tumor Segmentation (BraTS) Challenge have evaluated state-of-the-art machine learning methods to detect, characterize, and classify gliomas. However, it is unclear if the state-of-the-art methods can be widely implemented in SSA given the extensive use of lower-quality MRI technology, which produces poor image contrast and resolution and more importantly, the propensity for late presentation of disease at advanced stages as well as the unique characteristics of gliomas in SSA (i.e., suspected higher rates of gliomatosis cerebri). Thus, the BraTS-Africa Challenge provides a unique opportunity to include brain MRI glioma cases from SSA in global efforts through the BraTS Challenge to develop and evaluate computer-aided-diagnostic (CAD) methods for the detection and characterization of glioma in resource-limited settings, where the potential for CAD tools to transform healthcare are more likely.

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