no code implementations • 13 Sep 2022 • M. Ali Al-Radhawi, Shubham Tripathi, Yun Zhang, Eduardo D. Sontag, Herbert Levine
In such models, epigenetic factors are usually proposed to act on the chromatin regions directly involved in the expression of relevant genes.
no code implementations • 27 Nov 2020 • Dongya Jia, Jun Hyoung Park, Harsimran Kaur, Kwang Hwa Jung, Sukjin Yang, Shubham Tripathi, Madeline Galbraith, Youyuan Deng, Mohit Kumar Jolly, Benny Abraham Kaipparettu, Jose N. Onuchic, Herbert Levine
Cancer cells have the plasticity to adjust their metabolic phenotypes for survival and metastasis.
no code implementations • 25 Jul 2019 • Shubham Tripathi, Jianhua Xing, Herbert Levine, Mohit Kumar Jolly
Epithelial-Mesenchymal Transition (EMT), and the corresponding reverse process, Mesenchymal-Epithelial Transition (MET), are dynamic and reversible cellular programs orchestrated by many changes at biochemical and morphological levels.
no code implementations • 16 Apr 2019 • Dongya Jia, Xuefei Li, Federico Bocci, Shubham Tripathi, Youyuan Deng, Mohit Kumar Jolly, Jose N. Onuchic, Herbert Levine
In this review, we first discuss recent efforts combining theoretical and experimental approaches to elucidate mechanisms underlying EMT multi-stability (i. e. the existence of multiple stable phenotypes during EMT) and the properties of hybrid E/M phenotypes.
1 code implementation • 1 Feb 2017 • Deepak Gupta, Shubham Tripathi, Asif Ekbal, Pushpak Bhattacharyya
For the task of PoS tagging on Code-Mixed Indian Social Media Text, we develop a supervised system based on Conditional Random Field classifier.