no code implementations • 22 Dec 2022 • Andreas Mayer, Christopher J. Russo, Quentin Marcou, William Bialek, Benjamin D. Greenbaum
Biological and artificial neural networks routinely make reliable distinctions between similar inputs, and the rules for making these distinctions are learned.
no code implementations • 4 Jan 2021 • Hanrong Chen, Andreas Mayer, Vijay Balasubramanian
Some prokaryotes possess CRISPR-Cas systems that provide adaptive immunity to viruses guided by DNA segments called spacers acquired from invading phage.
1 code implementation • 1 Dec 2020 • Robert Marsland III, Owen Howell, Andreas Mayer, Pankaj Mehta
Regulatory T cells (Tregs) play a crucial role in mediating immune response.
1 code implementation • 21 Jul 2020 • Mario U. Gaimann, Maximilian Nguyen, Jonathan Desponds, Andreas Mayer
The adaptive immune system responds to pathogens by selecting clones of cells with specific receptors.
no code implementations • 10 Oct 2018 • Martin Carballo-Pacheco, Jonathan Desponds, Tatyana Gavrilchenko, Andreas Mayer, Roshan Prizak, Gautam Reddy, Ilya Nemenman, Thierry Mora
Crosstalk is often thought of as a deviation from optimal specific recognition, as the binding of non-cognate ligands can interfere with the detection of the receptor's cognate ligand, possibly leading to a false triggering of a downstream signaling pathway.