1 code implementation • 7 Mar 2022 • Manuel Reinhardt, Gašper Tkačik, Pieter Rein ten Wolde
The principal idea is to use the master equation to evaluate the exact conditional probability of an individual output trajectory for a given input trajectory, and average this via Monte Carlo sampling in trajectory space to obtain the mutual information.
no code implementations • 13 Oct 2021 • Benjamin Zoller, Thomas Gregor, Gašper Tkačik
The key question is therefore how this space can be navigated efficiently, to focus on mechanisms and models that are biologically relevant.
no code implementations • 15 Aug 2021 • Fabrizio Lombardi, Selver Pepić, Oren Shriki, Gašper Tkačik, Daniele De Martino
Importantly, the inferred parameters correlate with model-independent signatures of "closeness to criticality", indicating that the coexistence of scale-specific (neural oscillations) and scale-free (neuronal avalanches) dynamics in brain activity occurs close to a non-equilibrium critical point at the onset of self-sustained oscillations.
no code implementations • 18 Dec 2019 • William Bialek, Thomas Gregor, Gašper Tkačik
There is increasing evidence that protein binding to specific sites along DNA can activate the reading out of genetic information without coming into direct physical contact with the gene.
no code implementations • 24 May 2016 • Jan Humplik, Gašper Tkačik
Probabilistic models can be defined by an energy function, where the probability of each state is proportional to the exponential of the state's negative energy.