no code implementations • 29 Dec 2023 • Miloš Nikolić, Victoria Antonetti, Feng Liu, Gentian Muhaxheri, Mariela D. Petkova, Martin Scheeler, Eric M. Smith, William Bialek, Thomas Gregor
The body plan of the fruit fly is determined by the expression of just a handful of genes.
no code implementations • 10 Dec 2023 • Lauren McGough, Helena Casademunt, Miloš Nikolić, Mariela D. Petkova, Thomas Gregor, William Bialek
In a developing embryo, information about the position of cells is encoded in the concentrations of "morphogen" molecules.
no code implementations • 10 Aug 2023 • Netta Haroush, Michal Levo, Eric Wieschaus, Thomas Gregor
We simultaneously measure the spatiotemporal gap gene concentrations in hemizygous and homozygous gap mutants, and link these to eve activity.
no code implementations • 18 Apr 2023 • Po-Ta Chen, Benjamin Zoller, Michal Levo, Thomas Gregor
Specifically, we find that the durations of ON and OFF periods are linked.
no code implementations • 24 May 2022 • Fernando W. Rossine, Gabriel Vercelli, Corina E. Tarnita, Thomas Gregor
From these insights we construct a theoretical model that predicts how disturbances to amoeba growth rate and movement disrupt their predation efficiency.
no code implementations • 13 Oct 2021 • Benjamin Zoller, Thomas Gregor, Gašper Tkačik
The key question is therefore how this space can be navigated efficiently, to focus on mechanisms and models that are biologically relevant.
no code implementations • 31 Dec 2020 • Lev Barinov, Sergey Ryabichko, William Bialek, Thomas Gregor
There is growing appreciation that gene function is connected to the dynamic structure of the chromosome.
no code implementations • 31 Dec 2020 • Marianne Bauer, Mariela D. Petkova, Thomas Gregor, Eric F. Wieschaus, William Bialek
We argue that cells in the embryo can extract all the available information about their position, but only if the concentration measurements approach the physical limits to information capacity.
no code implementations • 18 Dec 2019 • William Bialek, Thomas Gregor, Gašper Tkačik
There is increasing evidence that protein binding to specific sites along DNA can activate the reading out of genetic information without coming into direct physical contact with the gene.