Search Results for author: Guisheng Fan

Found 5 papers, 3 papers with code

Simple, Efficient and Scalable Structure-aware Adapter Boosts Protein Language Models

1 code implementation23 Apr 2024 Yang Tan, Mingchen Li, Bingxin Zhou, Bozitao Zhong, Lirong Zheng, Pan Tan, Ziyi Zhou, Huiqun Yu, Guisheng Fan, Liang Hong

Fine-tuning Pre-trained protein language models (PLMs) has emerged as a prominent strategy for enhancing downstream prediction tasks, often outperforming traditional supervised learning approaches.

Representation Learning

PETA: Evaluating the Impact of Protein Transfer Learning with Sub-word Tokenization on Downstream Applications

1 code implementation26 Oct 2023 Yang Tan, Mingchen Li, Pan Tan, Ziyi Zhou, Huiqun Yu, Guisheng Fan, Liang Hong

Moreover, despite the wealth of benchmarks and studies in the natural language community, there remains a lack of a comprehensive benchmark for systematically evaluating protein language model quality.

Protein Language Model Transfer Learning

MedChatZH: a Better Medical Adviser Learns from Better Instructions

1 code implementation3 Sep 2023 Yang Tan, Mingchen Li, Zijie Huang, Huiqun Yu, Guisheng Fan

Generative large language models (LLMs) have shown great success in various applications, including question-answering (QA) and dialogue systems.

Question Answering

SESNet: sequence-structure feature-integrated deep learning method for data-efficient protein engineering

no code implementations29 Dec 2022 Mingchen Li, Liqi Kang, Yi Xiong, Yu Guang Wang, Guisheng Fan, Pan Tan, Liang Hong

Here, we develop SESNet, a supervised deep-learning model to predict the fitness for protein mutants by leveraging both sequence and structure information, and exploiting attention mechanism.

Data Augmentation

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