Search Results for author: Jacob Deasy

Found 7 papers, 3 papers with code

Generalising sequence models for epigenome predictions with tissue and assay embeddings

no code implementations22 Aug 2023 Jacob Deasy, Ron Schwessinger, Ferran Gonzalez, Stephen Young, Kim Branson

Sequence modelling approaches for epigenetic profile prediction have recently expanded in terms of sequence length, model size, and profile diversity.

Heavy-tailed denoising score matching

1 code implementation17 Dec 2021 Jacob Deasy, Nikola Simidjievski, Pietro Liò

Score-based model research in the last few years has produced state of the art generative models by employing Gaussian denoising score-matching (DSM).

Denoising

$\alpha$-VAEs : Optimising variational inference by learning data-dependent divergence skew

no code implementations ICML Workshop INNF 2021 Jacob Deasy, Tom Andrew McIver, Nikola Simidjievski, Pietro Lio

The {\em skew-geometric Jensen-Shannon divergence} $\left(\textrm{JS}^{\textrm{G}_{\alpha}}\right)$ allows for an intuitive interpolation between forward and reverse Kullback-Leibler (KL) divergence based on the skew parameter $\alpha$.

Denoising Variational Inference

Adaptive Prediction Timing for Electronic Health Records

1 code implementation5 Mar 2020 Jacob Deasy, Ari Ercole, Pietro Liò

In realistic scenarios, multivariate timeseries evolve over case-by-case time-scales.

Impact of novel aggregation methods for flexible, time-sensitive EHR prediction without variable selection or cleaning

no code implementations17 Sep 2019 Jacob Deasy, Ari Ercole, Pietro Liò

Dynamic assessment of patient status (e. g. by an automated, continuously updated assessment of outcome) in the Intensive Care Unit (ICU) is of paramount importance for early alerting, decision support and resource allocation.

Variable Selection

Dynamic survival prediction in intensive care units from heterogeneous time series without the need for variable selection or pre-processing

no code implementations13 Sep 2019 Jacob Deasy, Pietro Liò, Ari Ercole

Recordings in the first few hours of a patient's stay were found to be strongly predictive of mortality, outperforming models using SAPS II and OASIS scores within just 2 hours and achieving a state of the art Area Under the Receiver Operating Characteristic (AUROC) value of 0. 80 (95% CI 0. 79-0. 80) at 12 hours vs 0. 70 and 0. 66 for SAPS II and OASIS at 24 hours respectively.

Decision Making Feature Engineering +5

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