Search Results for author: Manal Helal

Found 6 papers, 1 papers with code

Defining Reference Sequences for Nocardia Species by Similarity and Clustering Analyses of 16S rRNA Gene Sequence Data

no code implementations29 Nov 2023 Manal Helal, Fanrong Kong, Sharon C. A. Chen, Michael Bain, Richard Christen, Vitali Sintchenko

The most representative 16S rRNA sequences for individual Nocardia species have been identified as 'centroids' in respective clusters from which the distances to all other sequences were minimized; 110 16S rRNA gene sequences with identifications recorded only at the genus level were classified using machine learning methods.

Clustering Dimensionality Reduction

Linear normalised hash function for clustering gene sequences and identifying reference sequences from multiple sequence alignments

no code implementations29 Nov 2023 Manal Helal, Fanrong Kong, Sharon C-A Chen, Fei Zhou, Dominic E Dwyer, John Potter, Vitali Sintchenko

The combination of MSA with the linear mapping hash function is a computationally efficient way of gene sequence clustering and can be a valuable tool for the assessment of similarity, clustering of different microbial genomes, identifying reference sequences, and for the study of evolution of bacteria and viruses.

Clustering Dimensionality Reduction +1

High Performance Multiple Sequence Alignment Algorithms for Comparison of Microbial Genomes

no code implementations29 Nov 2023 Manal Helal, Hossam El-Gindy, Bruno Gaeta, Vitali Sinchenko

Advances in gene sequencing have enabled in silico analyses of microbial genomes and have led to the revision of concepts of microbial taxonomy and evolution.

Multiple Sequence Alignment

Dynamic Programming Algorithms for Discovery of Antibiotic Resistance in Microbial Genomes

no code implementations29 Nov 2023 Manal Helal, Vitali Sintchenko

The translation of comparative genomics into clinical decision support tools often depends on the quality of sequence alignments.

Multiple Sequence Alignment

Chat Failures and Troubles: Reasons and Solutions

no code implementations7 Sep 2023 Manal Helal, Patrick Holthaus, Gabriella Lakatos, Farshid Amirabdollahian

This paper examines some common problems in Human-Robot Interaction (HRI) causing failures and troubles in Chat.

reinforcement-learning

Enhancing Deep Learning Models through Tensorization: A Comprehensive Survey and Framework

1 code implementation5 Sep 2023 Manal Helal

The burgeoning growth of public domain data and the increasing complexity of deep learning model architectures have underscored the need for more efficient data representation and analysis techniques.

blind source separation

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