Search Results for author:
Found 15 papers, 2 papers with code
Anti-seizure medication tapering is associated with delta band power reduction in a dose, region and time-dependent manner
Anti-seizure medications (ASMs) are the primary treatment for epilepsy, yet medication tapering effects have not been investigated in a dose, region, and time-dependent manner, despite their potential impact on research and clinical practice.
Multi-centre normative brain mapping of intracranial EEG lifespan patterns in the human brain
Results: Recording site significantly impacted normative icEEG maps in all frequency bands, and age was a more influential predictor of band power than sex.
Alpha rhythm slowing in temporal epilepsy across Scalp EEG and MEG
Alpha slowing in TLE was found in both EEG and MEG recordings.
Incomplete resection of the icEEG seizure onset zone is not associated with post-surgical outcomes
Retrospective analysis of icEEG recordings from 63 subjects (735 seizures) identified seizure onset regions through visual inspection and algorithmic delineation.
Multiscale cortical morphometry reveals pronounced regional and scale-dependent variations across the lifespan
Motivation: Characterising the changes in cortical morphology across the lifespan is fundamental for a range of research and clinical applications.
Identifying epileptogenic abnormality by decomposing intracranial EEG and MEG power spectra
Combining periodic and aperiodic abnormalities improved performance, similar to the complete band power approach.
Interictal MEG abnormalities to guide intracranial electrode implantation and predict surgical outcome
Finally, we assessed if the implantation of electrodes in abnormal tissue, and resection of the strongest abnormalities determined by MEG and iEEG explained surgical outcome.
Identifying epileptogenic abnormalities through spatial clustering of MEG interictal band power
We quantified the spatial overlap between the abnormality cluster and subsequent resection, hypothesising a greater overlap in seizure-free patients.
Neuro-evolutionary evidence for a universal fractal primate brain shape
To demonstrate the importance of this new understanding, we show a scale-dependent effect of ageing on brain morphology.
MEG abnormalities and mechanisms of surgical failure in neocortical epilepsy
Resting-state MEG data were acquired for 70 healthy controls and 32 patients with refractory neocortical epilepsy.
A library of quantitative markers of seizure severity
In individual patients, 71% had a moderate to large difference (ranksum r > 0. 3) between focal and subclinical seizures in three or more markers.
Intracranial EEG structure-function coupling predicts surgical outcomes in focal epilepsy
We investigated pre-operative structure-function coupling at two spatial scales a) at the global iEEG network level and b) at the resolution of individual iEEG electrode contacts using virtual surgeries.
Volumetric and structural connectivity abnormalities co-localise in TLE
We computed grey matter volumetric changes and white matter structural connectivity abnormalities in 144 patients with unilateral TLE and 96 healthy controls.
Chronic iEEG recordings and interictal spike rate reveal multiscale temporal modulations in seizure states
We then compared SNS occurrence and duration to (1) time since implantation and (2) patient-specific circadian and multidien cycles in interictal spike rate.
Seizure pathways and seizure durations can vary independently within individual patients with focal epilepsy
However, it is unclear whether seizures following the same pathway will have the same duration or if these features can vary independently.
