AIRIVA: A Deep Generative Model of Adaptive Immune Repertoires

no code implementations • 26 Apr 2023 • Melanie F. Pradier, Niranjani Prasad, Paidamoyo Chapfuwa, Sahra Ghalebikesabi, Max Ilse, Steven Woodhouse, Rebecca Elyanow, Javier Zazo, Javier Gonzalez, Julia Greissl, Edward Meeds

Recent advances in immunomics have shown that T-cell receptor (TCR) signatures can accurately predict active or recent infection by leveraging the high specificity of TCR binding to disease antigens.

Specificity