1 code implementation • 8 Feb 2024 • Patrick Wienholt, Alexander Hermans, Firas Khader, Behrus Puladi, Bastian Leibe, Christiane Kuhl, Sven Nebelung, Daniel Truhn
This study investigates the application of ordinal regression methods for categorizing disease severity in chest radiographs.
1 code implementation • 1 Oct 2023 • Soroosh Tayebi Arasteh, Christiane Kuhl, Marwin-Jonathan Saehn, Peter Isfort, Daniel Truhn, Sven Nebelung
So far, the impact of training strategy, i. e., local versus collaborative, on the diagnostic on-domain and off-domain performance of AI models interpreting chest radiographs has not been assessed.
1 code implementation • 29 Sep 2023 • Tianyu Han, Laura Žigutytė, Luisa Huck, Marc Huppertz, Robert Siepmann, Yossi Gandelsman, Christian Blüthgen, Firas Khader, Christiane Kuhl, Sven Nebelung, Jakob Kather, Daniel Truhn
Current techniques for evaluating deep learning models cannot visualize confounding factors at a diagnostic level.
1 code implementation • 29 Sep 2023 • Tianyu Han, Sven Nebelung, Firas Khader, Tianci Wang, Gustav Mueller-Franzes, Christiane Kuhl, Sebastian Försch, Jens Kleesiek, Christoph Haarburger, Keno K. Bressem, Jakob Nikolas Kather, Daniel Truhn
We validate our findings in a set of 1, 038 incorrect biomedical facts.
1 code implementation • 27 Aug 2023 • Soroosh Tayebi Arasteh, Tianyu Han, Mahshad Lotfinia, Christiane Kuhl, Jakob Nikolas Kather, Daniel Truhn, Sven Nebelung
A knowledge gap persists between machine learning (ML) developers (e. g., data scientists) and practitioners (e. g., clinicians), hampering the full utilization of ML for clinical data analysis.
2 code implementations • 15 Aug 2023 • Soroosh Tayebi Arasteh, Leo Misera, Jakob Nikolas Kather, Daniel Truhn, Sven Nebelung
In this study, we explored if SSL for pre-training on non-medical images can be applied to chest radiographs and how it compares to supervised pre-training on non-medical images and on medical images.
1 code implementation • 10 Jun 2023 • Soroosh Tayebi Arasteh, Mahshad Lotfinia, Teresa Nolte, Marwin Saehn, Peter Isfort, Christiane Kuhl, Sven Nebelung, Georgios Kaissis, Daniel Truhn
We specifically investigate the performance of models trained with DP as compared to models trained without DP on data from institutions that the model had not seen during its training (i. e., external validation) - the situation that is reflective of the clinical use of AI models.
no code implementations • 11 May 2023 • Firas Khader, Gustav Müller-Franzes, Tianyu Han, Sven Nebelung, Christiane Kuhl, Johannes Stegmaier, Daniel Truhn
X-rays are widely available and even if the CT reconstructed from these radiographs is not a replacement of a complete CT in the diagnostic setting, it might serve to spare the patients from radiation where a CT is only acquired for rough measurements such as determining organ size.
no code implementations • 11 May 2023 • Firas Khader, Jakob Nikolas Kather, Tianyu Han, Sven Nebelung, Christiane Kuhl, Johannes Stegmaier, Daniel Truhn
However, while the conventional transformer allows for a simultaneous processing of a large set of input tokens, the computational demand scales quadratically with the number of input tokens and thus quadratically with the number of image patches.
1 code implementation • 18 Apr 2023 • Gustav Müller-Franzes, Fritz Müller-Franzes, Luisa Huck, Vanessa Raaff, Eva Kemmer, Firas Khader, Soroosh Tayebi Arasteh, Teresa Nolte, Jakob Nikolas Kather, Sven Nebelung, Christiane Kuhl, Daniel Truhn
Accurate and automatic segmentation of fibroglandular tissue in breast MRI screening is essential for the quantification of breast density and background parenchymal enhancement.
2 code implementations • 3 Feb 2023 • Soroosh Tayebi Arasteh, Alexander Ziller, Christiane Kuhl, Marcus Makowski, Sven Nebelung, Rickmer Braren, Daniel Rueckert, Daniel Truhn, Georgios Kaissis
In this work, we evaluated the effect of privacy-preserving training of AI models regarding accuracy and fairness compared to non-private training.
1 code implementation • 18 Dec 2022 • Firas Khader, Gustav Mueller-Franzes, Tianci Wang, Tianyu Han, Soroosh Tayebi Arasteh, Christoph Haarburger, Johannes Stegmaier, Keno Bressem, Christiane Kuhl, Sven Nebelung, Jakob Nikolas Kather, Daniel Truhn
Multimodal deep learning has been used to predict clinical endpoints and diagnoses from clinical routine data.
1 code implementation • 14 Dec 2022 • Gustav Müller-Franzes, Jan Moritz Niehues, Firas Khader, Soroosh Tayebi Arasteh, Christoph Haarburger, Christiane Kuhl, Tianci Wang, Tianyu Han, Sven Nebelung, Jakob Nikolas Kather, Daniel Truhn
The success of Deep Learning applications critically depends on the quality and scale of the underlying training data.
1 code implementation • 24 Nov 2022 • Soroosh Tayebi Arasteh, Peter Isfort, Marwin Saehn, Gustav Mueller-Franzes, Firas Khader, Jakob Nikolas Kather, Christiane Kuhl, Sven Nebelung, Daniel Truhn
Due to the rapid advancements in recent years, medical image analysis is largely dominated by deep learning (DL).
1 code implementation • 7 Nov 2022 • Firas Khader, Gustav Mueller-Franzes, Soroosh Tayebi Arasteh, Tianyu Han, Christoph Haarburger, Maximilian Schulze-Hagen, Philipp Schad, Sandy Engelhardt, Bettina Baessler, Sebastian Foersch, Johannes Stegmaier, Christiane Kuhl, Sven Nebelung, Jakob Nikolas Kather, Daniel Truhn
Furthermore, we demonstrate that synthetic images can be used in a self-supervised pre-training and improve the performance of breast segmentation models when data is scarce (dice score 0. 91 vs. 0. 95 without vs. with synthetic data).
1 code implementation • 22 Nov 2021 • Tianyu Han, Jakob Nikolas Kather, Federico Pedersoli, Markus Zimmermann, Sebastian Keil, Maximilian Schulze-Hagen, Marc Terwoelbeck, Peter Isfort, Christoph Haarburger, Fabian Kiessling, Volkmar Schulz, Christiane Kuhl, Sven Nebelung, Daniel Truhn
We present a generic solution for this problem by a methodology that allows the prediction of progression risk and morphology in individuals using a latent extrapolation optimization approach.
1 code implementation • 25 Nov 2020 • Tianyu Han, Sven Nebelung, Federico Pedersoli, Markus Zimmermann, Maximilian Schulze-Hagen, Michael Ho, Christoph Haarburger, Fabian Kiessling, Christiane Kuhl, Volkmar Schulz, Daniel Truhn
Contrary to previous research on adversarially trained models, we found that the accuracy of such models was equal to standard models when sufficiently large datasets and dual batch norm training were used.