Search Results for author: Charles K. Fisher

Found 13 papers, 3 papers with code

Prognostic Covariate Adjustment for Logistic Regression in Randomized Controlled Trials

no code implementations29 Feb 2024 Yunfan Li, Arman Sabbaghi, Jonathan R. Walsh, Charles K. Fisher

We demonstrate that prognostic score adjustment in logistic regression increases the power of the Wald test for the conditional odds ratio under a fixed sample size, or alternatively reduces the necessary sample size to achieve a desired power, compared to the unadjusted analysis.

regression

Bayesian Prognostic Covariate Adjustment With Additive Mixture Priors

no code implementations27 Oct 2023 Alyssa M. Vanderbeek, Arman Sabbaghi, Jon R. Walsh, Charles K. Fisher

We propose a new Bayesian prognostic covariate adjustment methodology, referred to as Bayesian PROCOVA, that combines these two strategies.

Decision Making

Neural Boltzmann Machines

1 code implementation15 May 2023 Alex H. Lang, Anton D. Loukianov, Charles K. Fisher

Conditional generative models are capable of using contextual information as input to create new imaginative outputs.

Can RBMs be trained with zero step contrastive divergence?

no code implementations3 Nov 2022 Charles K. Fisher

Restricted Boltzmann Machines (RBMs) are probabilistic generative models that can be trained by maximum likelihood in principle, but are usually trained by an approximate algorithm called Contrastive Divergence (CD) in practice.

Modeling Disease Progression in Mild Cognitive Impairment and Alzheimer's Disease with Digital Twins

no code implementations24 Dec 2020 Daniele Bertolini, Anton D. Loukianov, Aaron M. Smith, David Li-Bland, Yannick Pouliot, Jonathan R. Walsh, Charles K. Fisher

Alzheimer's Disease (AD) is a neurodegenerative disease that affects subjects in a broad range of severity and is assessed in clinical trials with multiple cognitive and functional instruments.

Generating Digital Twins with Multiple Sclerosis Using Probabilistic Neural Networks

no code implementations4 Feb 2020 Jonathan R. Walsh, Aaron M. Smith, Yannick Pouliot, David Li-Bland, Anton Loukianov, Charles K. Fisher

Multiple Sclerosis (MS) is a neurodegenerative disorder characterized by a complex set of clinical assessments.

Boltzmann Encoded Adversarial Machines

1 code implementation23 Apr 2018 Charles K. Fisher, Aaron M. Smith, Jonathan R. Walsh

Restricted Boltzmann Machines (RBMs) are a class of generative neural network that are typically trained to maximize a log-likelihood objective function.

A high-bias, low-variance introduction to Machine Learning for physicists

7 code implementations23 Mar 2018 Pankaj Mehta, Marin Bukov, Ching-Hao Wang, Alexandre G. R. Day, Clint Richardson, Charles K. Fisher, David J. Schwab

The purpose of this review is to provide an introduction to the core concepts and tools of machine learning in a manner easily understood and intuitive to physicists.

BIG-bench Machine Learning Clustering +2

Bayesian feature selection with strongly-regularizing priors maps to the Ising Model

no code implementations3 Nov 2014 Charles K. Fisher, Pankaj Mehta

Identifying small subsets of features that are relevant for prediction and/or classification tasks is a central problem in machine learning and statistics.

Bayesian Inference feature selection +1

Variational Pseudolikelihood for Regularized Ising Inference

no code implementations24 Sep 2014 Charles K. Fisher

I propose a variational approach to maximum pseudolikelihood inference of the Ising model.

Fast Bayesian Feature Selection for High Dimensional Linear Regression in Genomics via the Ising Approximation

no code implementations30 Jul 2014 Charles K. Fisher, Pankaj Mehta

Feature selection, identifying a subset of variables that are relevant for predicting a response, is an important and challenging component of many methods in statistics and machine learning.

feature selection regression

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