no code implementations • 18 Feb 2024 • Felix Lambrecht, Andreas Kröpelin, Mario Lüttich, Michael Habeck, David Haselbach, Holger Stark
CowScape analyzes an entire cryo-EM dataset and thereby obtains a quantitative description of structural variability of macromolecular complexes that represents the biochemically relevant conformational space.
1 code implementation • 4 Apr 2023 • Pavol Harar, Lukas Herrmann, Philipp Grohs, David Haselbach
A key shortcoming of these supervised learning methods is their need for large training data sets, typically generated from particle models in conjunction with complex numerical forward models simulating the physics of transmission electron microscopes.