no code implementations • 8 Sep 2023 • Sofiane Ouaari, Ali Burak Ünal, Mete Akgün, Nico Pfeifer
Several domains increasingly rely on machine learning in their applications.
1 code implementation • 16 Jan 2023 • Jonas Christian Ditz, Jacqueline Wistuba-Hamprecht, Timo Maier, Rolf Fendel, Nico Pfeifer, Bernhard Reuter
Results: We developed PlasmoFAB, a curated benchmark that can be used to train machine learning methods for the exploration of Plasmodium falciparum protein antigen candidates.
no code implementations • 7 Dec 2022 • Marius de Arruda Botelho Herr, Michael Graf, Peter Placzek, Florian König, Felix Bötte, Tyra Stickel, David Hieber, Lukas Zimmermann, Michael Slupina, Christopher Mohr, Stephanie Biergans, Mete Akgün, Nico Pfeifer, Oliver Kohlbacher
The need for data privacy and security -- enforced through increasingly strict data protection regulations -- renders the use of healthcare data for machine learning difficult.
1 code implementation • 2 Dec 2022 • Jonas C. Ditz, Bernhard Reuter, Nico Pfeifer
By combining convolutional kernel networks with pathway-induced kernels, our method enables robust and interpretable end-to-end learning on omics datasets ranging in size from a few hundred to several hundreds of thousands of samples.
no code implementations • 7 Feb 2022 • Ali Burak Ünal, Nico Pfeifer, Mete Akgün
To address this, we propose a secure 3-party computation framework, CECILIA, offering PP building blocks to enable complex operations privately.
1 code implementation • 3 Nov 2021 • Jonas C. Ditz, Bernhard Reuter, Nico Pfeifer
Our proposed method can be utilized on DNA and protein sequences.
no code implementations • 17 Feb 2021 • Ali Burak Ünal, Nico Pfeifer, Mete Akgün
In this setting, it can also be a problem to compute the global AUC, since the labels might also contain privacy-sensitive information.
no code implementations • 4 Dec 2020 • Ali Burak Ünal, Mete Akgün, Nico Pfeifer
We address this problem by introducing ESCAPED, which stands for Efficient SeCure And PrivatE Dot product framework, enabling the computation of the dot product of vectors from multiple sources on a third-party, which later trains kernel-based machine learning algorithms, while neither sacrificing privacy nor adding noise.
no code implementations • 6 Nov 2019 • Efe Bozkir, Ali Burak Ünal, Mete Akgün, Enkelejda Kasneci, Nico Pfeifer
Eye tracking is handled as one of the key technologies for applications that assess and evaluate human attention, behavior, and biometrics, especially using gaze, pupillary, and blink behaviors.
no code implementations • 20 Nov 2018 • Nora K. Speicher, Nico Pfeifer
Due to the complexity of cancer, clustering algorithms have been used to disentangle the observed heterogeneity and identify cancer subtypes that can be treated specifically.
no code implementations • 2 Jan 2017 • Nora K. Speicher, Nico Pfeifer
Personalized treatment of patients based on tissue-specific cancer subtypes has strongly increased the efficacy of the chosen therapies.
no code implementations • 20 Dec 2016 • Lisa Handl, Adrin Jalali, Michael Scherer, Nico Pfeifer
We apply the model to the problem of age prediction based on DNA methylation data from a variety of tissues, and compare it to a standard model, which does not take heterogeneity into account.