TOP-Nav: Legged Navigation Integrating Terrain, Obstacle and Proprioception Estimation

no code implementations • 23 Apr 2024 • Junli Ren, YiKai Liu, Yingru Dai, Guijin Wang

Within the path planner, we present and integrate a terrain estimator that enables the robot to select waypoints on terrains with higher traversability while effectively avoiding obstacles.

Motion Planning

Unbiasing Enhanced Sampling on a High-dimensional Free Energy Surface with Deep Generative Model

no code implementations • 14 Dec 2023 • YiKai Liu, Tushar K. Ghosh, Guang Lin, Ming Chen

Biased enhanced sampling methods utilizing collective variables (CVs) are powerful tools for sampling conformational ensembles.

Density Estimation

Backdiff: a diffusion model for generalized transferable protein backmapping

no code implementations • 3 Oct 2023 • YiKai Liu, Ming Chen, Guang Lin

Despite recent progress in data-driven backmapping approaches, devising a backmapping method that can be universally applied across various CG models and proteins remains unresolved.

Drug Discovery Protein Design

EASE: An Easily-Customized Annotation System Powered by Efficiency Enhancement Mechanisms

no code implementations • 23 May 2023 • Naihao Deng, YiKai Liu, Mingye Chen, Winston Wu, Siyang Liu, Yulong Chen, Yue Zhang, Rada Mihalcea

Our results show that our system can meet the diverse needs of NLP researchers and significantly accelerate the annotation process.

Active Learning