Search Results for author: Yuzhu Li

Found 11 papers, 0 papers with code

Autonomous Quality and Hallucination Assessment for Virtual Tissue Staining and Digital Pathology

no code implementations29 Apr 2024 Luzhe Huang, Yuzhu Li, Nir Pillar, Tal Keidar Haran, William Dean Wallace, Aydogan Ozcan

Here, we present an autonomous quality and hallucination assessment method (termed AQuA), mainly designed for virtual tissue staining, while also being applicable to histochemical staining.

Image Generation

Automated HER2 Scoring in Breast Cancer Images Using Deep Learning and Pyramid Sampling

no code implementations1 Apr 2024 Sahan Yoruc Selcuk, Xilin Yang, Bijie Bai, Yijie Zhang, Yuzhu Li, Musa Aydin, Aras Firat Unal, Aditya Gomatam, Zhen Guo, Darrow Morgan Angus, Goren Kolodney, Karine Atlan, Tal Keidar Haran, Nir Pillar, Aydogan Ozcan

Human epidermal growth factor receptor 2 (HER2) is a critical protein in cancer cell growth that signifies the aggressiveness of breast cancer (BC) and helps predict its prognosis.

Multiplexed all-optical permutation operations using a reconfigurable diffractive optical network

no code implementations4 Feb 2024 Guangdong Ma, Xilin Yang, Bijie Bai, Jingxi Li, Yuhang Li, Tianyi Gan, Che-Yung Shen, Yijie Zhang, Yuzhu Li, Mona Jarrahi, Aydogan Ozcan

We demonstrated the feasibility of this reconfigurable multiplexed diffractive design by approximating 256 randomly selected permutation matrices using K=4 rotatable diffractive layers.

Virtual histological staining of unlabeled autopsy tissue

no code implementations2 Aug 2023 Yuzhu Li, Nir Pillar, Jingxi Li, Tairan Liu, Di wu, Songyu Sun, Guangdong Ma, Kevin De Haan, Luzhe Huang, Sepehr Hamidi, Anatoly Urisman, Tal Keidar Haran, William Dean Wallace, Jonathan E. Zuckerman, Aydogan Ozcan

Histological examination is a crucial step in an autopsy; however, the traditional histochemical staining of post-mortem samples faces multiple challenges, including the inferior staining quality due to autolysis caused by delayed fixation of cadaver tissue, as well as the resource-intensive nature of chemical staining procedures covering large tissue areas, which demand substantial labor, cost, and time.

Image Registration

Deep Learning-enabled Virtual Histological Staining of Biological Samples

no code implementations13 Nov 2022 Bijie Bai, Xilin Yang, Yuzhu Li, Yijie Zhang, Nir Pillar, Aydogan Ozcan

Histological staining is the gold standard for tissue examination in clinical pathology and life-science research, which visualizes the tissue and cellular structures using chromatic dyes or fluorescence labels to aid the microscopic assessment of tissue.

RISE-Based Adaptive Control with Mass-Inertia Parameter Estimation for Aerial Transportation of Multi-Rotor UAVs

no code implementations17 Sep 2022 Shuyang Shi, Yuzhu Li, Wei Dong

Then, adaptive estimation laws for mass-inertia parameters are designed based on a filter operation.

Virtual stain transfer in histology via cascaded deep neural networks

no code implementations14 Jul 2022 Xilin Yang, Bijie Bai, Yijie Zhang, Yuzhu Li, Kevin De Haan, Tairan Liu, Aydogan Ozcan

Unlike a single neural network structure which only takes one stain type as input to digitally output images of another stain type, C-DNN first uses virtual staining to transform autofluorescence microscopy images into H&E and then performs stain transfer from H&E to the domain of the other stain in a cascaded manner.

Virtual staining of defocused autofluorescence images of unlabeled tissue using deep neural networks

no code implementations6 Jul 2022 Yijie Zhang, Luzhe Huang, Tairan Liu, Keyi Cheng, Kevin De Haan, Yuzhu Li, Bijie Bai, Aydogan Ozcan

Here, we introduce a fast virtual staining framework that can stain defocused autofluorescence images of unlabeled tissue, achieving equivalent performance to virtual staining of in-focus label-free images, also saving significant imaging time by lowering the microscope's autofocusing precision.

Collaborative Inference

Rapid and stain-free quantification of viral plaque via lens-free holography and deep learning

no code implementations30 Jun 2022 Tairan Liu, Yuzhu Li, Hatice Ceylan Koydemir, Yijie Zhang, Ethan Yang, Merve Eryilmaz, Hongda Wang, Jingxi Li, Bijie Bai, Guangdong Ma, Aydogan Ozcan

We also demonstrated that this data-driven plaque assay offers the capability of quantifying the infected area of the cell monolayer, performing automated counting and quantification of PFUs and virus-infected areas over a 10-fold larger dynamic range of virus concentration than standard viral plaque assays.

Specificity Virology

Deep Learning-enabled Detection and Classification of Bacterial Colonies using a Thin Film Transistor (TFT) Image Sensor

no code implementations7 May 2022 Yuzhu Li, Tairan Liu, Hatice Ceylan Koydemir, Hongda Wang, Keelan O'Riordan, Bijie Bai, Yuta Haga, Junji Kobashi, Hitoshi Tanaka, Takaya Tamaru, Kazunori Yamaguchi, Aydogan Ozcan

Due to the large scalability, ultra-large field-of-view, and low cost of the TFT-based image sensors, this platform can be integrated with each agar plate to be tested and disposed of after the automated CFU count.

Cultural Vocal Bursts Intensity Prediction

Label-free virtual HER2 immunohistochemical staining of breast tissue using deep learning

no code implementations8 Dec 2021 Bijie Bai, Hongda Wang, Yuzhu Li, Kevin De Haan, Francesco Colonnese, Yujie Wan, Jingyi Zuo, Ngan B. Doan, Xiaoran Zhang, Yijie Zhang, Jingxi Li, Wenjie Dong, Morgan Angus Darrow, Elham Kamangar, Han Sung Lee, Yair Rivenson, Aydogan Ozcan

The immunohistochemical (IHC) staining of the human epidermal growth factor receptor 2 (HER2) biomarker is widely practiced in breast tissue analysis, preclinical studies and diagnostic decisions, guiding cancer treatment and investigation of pathogenesis.

Generative Adversarial Network whole slide images

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