2 code implementations • Nature 2016 • Alistair E.W. Johnson, Tom J. Pollard, Lu Shen, Li-wei H. Lehman, Mengling Feng, Mohammad Ghassemi, Benjamin Moody, Peter Szolovits, Leo Anthony Celi, Roger G. Mark
MIMIC-III (‘Medical Information Mart for Intensive Care’) is a large, single-center database comprising information relating to patients admitted to critical care units at a large tertiary care hospital.
no code implementations • 25 Mar 2017 • Sebastian Gehrmann, Franck Dernoncourt, Yeran Li, Eric T. Carlson, Joy T. Wu, Jonathan Welt, John Foote Jr., Edward T. Moseley, David W. Grant, Patrick D. Tyler, Leo Anthony Celi
We assess the performance of deep learning algorithms and compare them with classical NLP approaches.
no code implementations • 23 May 2017 • Harini Suresh, Nathan Hunt, Alistair Johnson, Leo Anthony Celi, Peter Szolovits, Marzyeh Ghassemi
Real-time prediction of clinical interventions remains a challenge within intensive care units (ICUs).
no code implementations • 23 May 2017 • Aniruddh Raghu, Matthieu Komorowski, Leo Anthony Celi, Peter Szolovits, Marzyeh Ghassemi
In this work, we propose a new approach to deduce optimal treatment policies for septic patients by using continuous state-space models and deep reinforcement learning.
no code implementations • 31 May 2018 • Omer Gottesman, Fredrik Johansson, Joshua Meier, Jack Dent, Dong-hun Lee, Srivatsan Srinivasan, Linying Zhang, Yi Ding, David Wihl, Xuefeng Peng, Jiayu Yao, Isaac Lage, Christopher Mosch, Li-wei H. Lehman, Matthieu Komorowski, Aldo Faisal, Leo Anthony Celi, David Sontag, Finale Doshi-Velez
Much attention has been devoted recently to the development of machine learning algorithms with the goal of improving treatment policies in healthcare.
1 code implementation • 30 Jun 2018 • Willie Boag, Harini Suresh, Leo Anthony Celi, Peter Szolovits, Marzyeh Ghassemi
In this work, we characterize the doctor-patient relationship using a machine learning-derived trust score.
no code implementations • 4 Aug 2018 • Daniele Ramazzotti, Peter Clardy, Leo Anthony Celi, David J. Stone, Robert S. Rudin
Comparing the period 2002-2005 vs. 2008-2011, we found a reduction in the use of vasopressors and inotropes among patients with the lowest severity who died within 30 days of ICU admission (41. 8 vs. 36. 2 hours, p<0. 001) but not among those with the highest severity.
1 code implementation • 11 Aug 2018 • Willie Boag, Harini Suresh, Leo Anthony Celi, Peter Szolovits, Marzyeh Ghassemi
There are established racial disparities in healthcare, including during end-of-life care, when poor communication and trust can lead to suboptimal outcomes for patients and their families.
Applications
1 code implementation • 4 Nov 2019 • Andrew Slavin Ross, Weiwei Pan, Leo Anthony Celi, Finale Doshi-Velez
Ensembles depend on diversity for improved performance.
no code implementations • 28 Jan 2020 • Xiaoli Liu, Pan Hu, Zhi Mao, Po-Chih Kuo, Peiyao Li, Chao Liu, Jie Hu, Deyu Li, Desen Cao, Roger G. Mark, Leo Anthony Celi, Zhengbo Zhang, Feihu Zhou
This study aims to develop an interpretable and generalizable model for early mortality prediction in elderly patients with MODS.
no code implementations • ICML 2020 • Omer Gottesman, Joseph Futoma, Yao Liu, Sonali Parbhoo, Leo Anthony Celi, Emma Brunskill, Finale Doshi-Velez
Off-policy evaluation in reinforcement learning offers the chance of using observational data to improve future outcomes in domains such as healthcare and education, but safe deployment in high stakes settings requires ways of assessing its validity.
no code implementations • LREC 2020 • Edward T. Moseley, Joy T. Wu, Jonathan Welt, John Foote, Patrick D. Tyler, David W. Grant, Eric T. Carlson, Sebastian Gehrmann, Franck Dernoncourt, Leo Anthony Celi
In this paper, we introduce a dataset for patient phenotyping, a task that is defined as the identification of whether a patient has a given medical condition (also referred to as clinical indication or phenotype) based on their patient note.
no code implementations • 31 Aug 2020 • Patrick Schwab, Arash Mehrjou, Sonali Parbhoo, Leo Anthony Celi, Jürgen Hetzel, Markus Hofer, Bernhard Schölkopf, Stefan Bauer
Coronavirus Disease 2019 (COVID-19) is an emerging respiratory disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with rapid human-to-human transmission and a high case fatality rate particularly in older patients.
no code implementations • 22 Dec 2020 • Amir Pouran Ben Veyseh, Franck Dernoncourt, Thien Huu Nguyen, Walter Chang, Leo Anthony Celi
To push forward research in this direction, we have organized two shared task for acronym identification and acronym disambiguation in scientific documents, named AI@SDU and AD@SDU, respectively.
no code implementations • 9 Jan 2021 • Kristine Zhang, Yuanheng Wang, Jianzhun Du, Brian Chu, Leo Anthony Celi, Ryan Kindle, Finale Doshi-Velez
Many batch RL health applications first discretize time into fixed intervals.
no code implementations • 16 Jan 2021 • Gloria Hyunjung Kwak, Christina Chen, Lowell Ling, Erina Ghosh, Leo Anthony Celi, Pan Hui
While hyperkalemia is often a complication of acute kidney injury (AKI), it also occurs in the absence of AKI.
no code implementations • 7 Jul 2021 • Behrooz Mamandipoor, Wesley Yeung, Louis Agha-Mir-Salim, David J. Stone, Venet Osmani, Leo Anthony Celi
Outcomes were defined based on increase or decrease of serum lactate levels between the groups.
no code implementations • 21 Jul 2021 • Imon Banerjee, Ananth Reddy Bhimireddy, John L. Burns, Leo Anthony Celi, Li-Ching Chen, Ramon Correa, Natalie Dullerud, Marzyeh Ghassemi, Shih-Cheng Huang, Po-Chih Kuo, Matthew P Lungren, Lyle Palmer, Brandon J Price, Saptarshi Purkayastha, Ayis Pyrros, Luke Oakden-Rayner, Chima Okechukwu, Laleh Seyyed-Kalantari, Hari Trivedi, Ryan Wang, Zachary Zaiman, Haoran Zhang, Judy W Gichoya
Methods: Using private and public datasets we evaluate: A) performance quantification of deep learning models to detect race from medical images, including the ability of these models to generalize to external environments and across multiple imaging modalities, B) assessment of possible confounding anatomic and phenotype population features, such as disease distribution and body habitus as predictors of race, and C) investigation into the underlying mechanism by which AI models can recognize race.
1 code implementation • 1 Sep 2021 • Joy Tzung-yu Wu, Miguel Ángel Armengol de la Hoz, Po-Chih Kuo, Joseph Alexander Paguio, Jasper Seth Yao, Edward Christopher Dee, Wesley Yeung, Jerry Jurado, Achintya Moulick, Carmelo Milazzo, Paloma Peinado, Paula Villares, Antonio Cubillo, José Felipe Varona, Hyung-Chul Lee, Alberto Estirado, José Maria Castellano, Leo Anthony Celi
We employed the best machine learning practices for clinical model development.
no code implementations • 28 Nov 2021 • Ramtin Keramati, Omer Gottesman, Leo Anthony Celi, Finale Doshi-Velez, Emma Brunskill
Off-policy policy evaluation methods for sequential decision making can be used to help identify if a proposed decision policy is better than a current baseline policy.
no code implementations • 8 May 2022 • Hammaad Adam, Ming Ying Yang, Kenrick Cato, Ioana Baldini, Charles Senteio, Leo Anthony Celi, Jiaming Zeng, Moninder Singh, Marzyeh Ghassemi
In this study, we investigate the level of implicit race information available to ML models and human experts and the implications of model-detectable differences in clinical notes.
1 code implementation • NAACL (ClinicalNLP) 2022 • Eric Lehman, Vladislav Lialin, Katelyn Y. Legaspi, Anne Janelle R. Sy, Patricia Therese S. Pile, Nicole Rose I. Alberto, Richard Raymund R. Ragasa, Corinna Victoria M. Puyat, Isabelle Rose I. Alberto, Pia Gabrielle I. Alfonso, Marianne Taliño, Dana Moukheiber, Byron C. Wallace, Anna Rumshisky, Jenifer J. Liang, Preethi Raghavan, Leo Anthony Celi, Peter Szolovits
The questions are generated by medical experts from 100+ MIMIC-III discharge summaries.
no code implementations • 16 Jul 2022 • Jonathan A. Sobel, Ronit Almog, Leo Anthony Celi, Michal Gaziel-Yablowitz, Danny Eytan, Joachim A. Behar
A datathon is a time-constrained competition involving data science applied to a specific problem.
no code implementations • 13 Nov 2022 • Ryan Wang, Li-Ching Chen, Lama Moukheiber, Mira Moukheiber, Dana Moukheiber, Zach Zaiman, Sulaiman Moukheiber, Tess Litchman, Kenneth Seastedt, Hari Trivedi, Rebecca Steinberg, Po-Chih Kuo, Judy Gichoya, Leo Anthony Celi
We further propose two fusion schemes, (1) model-level fusion, including bagging and stacking methods using MIMIC-CXR, and (2) data-level fusion, including multi-site data using MIMIC-CXR and Emory-CXR, and multi-modal using MIMIC-CXRs and MIMIC-IV EHR, to improve the overall model performance.
no code implementations • 26 Apr 2023 • Mingxuan Liu, Yilin Ning, Salinelat Teixayavong, Mayli Mertens, Jie Xu, Daniel Shu Wei Ting, Lionel Tim-Ee Cheng, Jasmine Chiat Ling Ong, Zhen Ling Teo, Ting Fang Tan, Ravi Chandran Narrendar, Fei Wang, Leo Anthony Celi, Marcus Eng Hock Ong, Nan Liu
In this paper, we discuss the misalignment between technical and clinical perspectives of AI fairness, highlight the barriers to AI fairness' translation to healthcare, advocate multidisciplinary collaboration to bridge the knowledge gap, and provide possible solutions to address the clinical concerns pertaining to AI fairness.
no code implementations • 22 May 2023 • Ming Ying Yang, Gloria Hyunjung Kwak, Tom Pollard, Leo Anthony Celi, Marzyeh Ghassemi
Social determinants of health (SDOH) -- the conditions in which people live, grow, and age -- play a crucial role in a person's health and well-being.
1 code implementation • 3 Aug 2023 • Matthieu Doutreligne, Tristan Struja, Judith Abecassis, Claire Morgand, Leo Anthony Celi, Gaël Varoquaux
We illustrate the various choices in studying the effect of albumin on sepsis mortality in the Medical Information Mart for Intensive Care database (MIMIC-IV).
no code implementations • 24 Oct 2023 • Gregory Holste, Yiliang Zhou, Song Wang, Ajay Jaiswal, Mingquan Lin, Sherry Zhuge, Yuzhe Yang, Dongkyun Kim, Trong-Hieu Nguyen-Mau, Minh-Triet Tran, Jaehyup Jeong, Wongi Park, Jongbin Ryu, Feng Hong, Arsh Verma, Yosuke Yamagishi, Changhyun Kim, Hyeryeong Seo, Myungjoo Kang, Leo Anthony Celi, Zhiyong Lu, Ronald M. Summers, George Shih, Zhangyang Wang, Yifan Peng
Many real-world image recognition problems, such as diagnostic medical imaging exams, are "long-tailed" $\unicode{x2013}$ there are a few common findings followed by many more relatively rare conditions.
no code implementations • 9 Nov 2023 • Joachim A. Behar, Jeremy Levy, Leo Anthony Celi
Re-calibration using transfer learning may not even be possible in some instances where reference labels of target domains are not available.
no code implementations • 21 Nov 2023 • Carolina A. M. Heming, Mohamed Abdalla, Monish Ahluwalia, Linglin Zhang, Hari Trivedi, Minjae Woo, Benjamin Fine, Judy Wawira Gichoya, Leo Anthony Celi, Laleh Seyyed-Kalantari
Clinical AI model reporting cards should be expanded to incorporate a broad bias reporting of both social and non-social factors.
no code implementations • 22 Dec 2023 • Yevgeniy Men, Jonathan Fhima, Leo Anthony Celi, Lucas Zago Ribeiro, Luis Filipe Nakayama, Joachim A. Behar
Diabetic retinopathy (DR) is a prevalent complication of diabetes associated with a significant risk of vision loss.
1 code implementation • 20 Jan 2024 • Kuan-Ting Kuo, Dana Moukheiber, Sebastian Cajas Ordonez, David Restrepo, Atika Rahman Paddo, Tsung-Yu Chen, Lama Moukheiber, Mira Moukheiber, Sulaiman Moukheiber, Saptarshi Purkayastha, Po-Chih Kuo, Leo Anthony Celi
In this study, our aim is to improve health equity in resource-constrained countries by exploring the effectiveness of high-resolution satellite imagery as a nontraditional and readily accessible data source.
no code implementations • 18 Mar 2024 • Stephen R. Pfohl, Heather Cole-Lewis, Rory Sayres, Darlene Neal, Mercy Asiedu, Awa Dieng, Nenad Tomasev, Qazi Mamunur Rashid, Shekoofeh Azizi, Negar Rostamzadeh, Liam G. McCoy, Leo Anthony Celi, Yun Liu, Mike Schaekermann, Alanna Walton, Alicia Parrish, Chirag Nagpal, Preeti Singh, Akeiylah Dewitt, Philip Mansfield, Sushant Prakash, Katherine Heller, Alan Karthikesalingam, Christopher Semturs, Joelle Barral, Greg Corrado, Yossi Matias, Jamila Smith-Loud, Ivor Horn, Karan Singhal
Large language models (LLMs) hold immense promise to serve complex health information needs but also have the potential to introduce harm and exacerbate health disparities.
no code implementations • 18 Apr 2024 • David Restrepo, Chenwei Wu, Constanza Vásquez-Venegas, Luis Filipe Nakayama, Leo Anthony Celi, Diego M López
In the big data era, integrating diverse data modalities poses significant challenges, particularly in complex fields like healthcare.