no code implementations • 11 Apr 2016 • Gary B. Huang, Louis K. Scheffer, Stephen M. Plaza
This discrepancy can, in part, be attributed to several factors: obtaining neuronal shapes is a prerequisite first step in extracting a connectome, manual tracing is much more time-consuming than annotating synapses, and neuronal contact area can be used as a proxy for synapses in determining connections.
1 code implementation • 1 Apr 2016 • Stephen M. Plaza, Stuart E. Berg
In this paper, we propose a novel strategy to apply such segmentation on very large datasets that exceed the capacity of a single machine.
Electron Microscopy Image Segmentation Image Segmentation +2
1 code implementation • 5 Sep 2014 • Ting Zhao, Stephen M. Plaza
Mapping the connectivity of neurons in the brain (i. e., connectomics) is a challenging problem due to both the number of connections in even the smallest organisms and the nanometer resolution required to resolve them.
no code implementations • 5 Sep 2014 • Stephen M. Plaza, Toufiq Parag, Gary B. Huang, Donald J. Olbris, Mathew A. Saunders, Patricia K. Rivlin
Reconstructing neuronal circuits at the level of synapses is a central problem in neuroscience and becoming a focus of the emerging field of connectomics.
1 code implementation • 3 Sep 2014 • Stephen M. Plaza
In this paper, we propose a new strategy, focused proofreading, that works with automatic segmentation and aims to limit proofreading to the regions of a dataset that are most impactful to the resulting circuit.