Search Results for author: Christof A. Bertram

Found 28 papers, 12 papers with code

Systematic Review of Methods and Prognostic Value of Mitotic Activity. Part 2: Canine Tumors

no code implementations31 May 2023 Christof A. Bertram, Taryn A. Donovan, Alexander Bartel

The goal of this systematic review is to scholarly analyze the methods and prognostic relevance of histologically measuring mitotic activity in canine tumors.

Systematic Review of Methods and Prognostic Value of Mitotic Activity. Part 1: Feline Tumors

no code implementations2 May 2023 Christof A. Bertram, Taryn A. Donovan, Alexander Bartel

The goal of this systematic review is scholarly analysis of all available references on mitotic activity in feline tumors, and to provide an overview of the measuring methods and prognostic value.

Multi-Scanner Canine Cutaneous Squamous Cell Carcinoma Histopathology Dataset

1 code implementation11 Jan 2023 Frauke Wilm, Marco Fragoso, Christof A. Bertram, Nikolas Stathonikos, Mathias Öttl, Jingna Qiu, Robert Klopfleisch, Andreas Maier, Katharina Breininger, Marc Aubreville

Additionally, to quantify the inherent scanner-induced domain shift, we train a tumor segmentation network on each scanner subset and evaluate the performance both in- and cross-domain.

Domain Generalization Tumor Segmentation

Deep learning-based Subtyping of Atypical and Normal Mitoses using a Hierarchical Anchor-Free Object Detector

1 code implementation12 Dec 2022 Marc Aubreville, Jonathan Ganz, Jonas Ammeling, Taryn A. Donovan, Rutger H. J. Fick, Katharina Breininger, Christof A. Bertram

In this work, we perform, for the first time, automatic subtyping of mitotic figures into normal and atypical categories according to characteristic morphological appearances of the different phases of mitosis.

object-detection Object Detection

Enabling Collagen Quantification on HE-stained Slides Through Stain Deconvolution and Restained HE-HES

no code implementations17 Nov 2022 Guillaume Balezo, Christof A. Bertram, Cyprien Tilmant, Stéphanie Petit, Saima Ben Hadj, Rutger H. J. Fick

In histology, the presence of collagen in the extra-cellular matrix has both diagnostic and prognostic value for cancer malignancy, and can be highlighted by adding Saffron (S) to a routine Hematoxylin and Eosin (HE) staining.

Pan-tumor CAnine cuTaneous Cancer Histology (CATCH) dataset

1 code implementation27 Jan 2022 Frauke Wilm, Marco Fragoso, Christian Marzahl, Jingna Qiu, Chloé Puget, Laura Diehl, Christof A. Bertram, Robert Klopfleisch, Andreas Maier, Katharina Breininger, Marc Aubreville

Due to morphological similarities, the differentiation of histologic sections of cutaneous tumors into individual subtypes can be challenging.

whole slide images

Learning to be EXACT, Cell Detection for Asthma on Partially Annotated Whole Slide Images

no code implementations13 Jan 2021 Christian Marzahl, Christof A. Bertram, Frauke Wilm, Jörn Voigt, Ann K. Barton, Robert Klopfleisch, Katharina Breininger, Andreas Maier, Marc Aubreville

We evaluated our pipeline in a cross-validation setup with a fixed training set using a dataset of six equine WSIs of which four are partially annotated and used for training, and two fully annotated WSI are used for validation and testing.

Cell Detection object-detection +2

Learning New Tricks from Old Dogs -- Inter-Species, Inter-Tissue Domain Adaptation for Mitotic Figure Assessment

no code implementations25 Nov 2019 Marc Aubreville, Christof A. Bertram, Samir Jabari, Christian Marzahl, Robert Klopfleisch, Andreas Maier

We were able to show that domain adversarial training considerably improves accuracy when applying mitotic figure classification learned from the canine on the human data sets (up to +12. 8% in accuracy) and is thus a helpful method to transfer knowledge from existing data sets to new tissue types and species.

Domain Adaptation

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