1 code implementation • EMNLP (ClinicalNLP) 2020 • Yifan Peng, SungWon Lee, Daniel C. Elton, Thomas Shen, Yu-Xing Tang, Qingyu Chen, Shuai Wang, Yingying Zhu, Ronald Summers, Zhiyong Lu
We then introduce an end-to-end approach based on the combination of rules and transformer-based methods to detect these abdominal lymph node mentions and classify their types from the MRI radiology reports.
1 code implementation • 15 Mar 2024 • Pagnarasmey Pit, Xingjun Ma, Mike Conway, Qingyu Chen, James Bailey, Henry Pit, Putrasmey Keo, Watey Diep, Yu-Gang Jiang
Large Language Models (LLMs) have gained significant popularity for their application in various everyday tasks such as text generation, summarization, and information retrieval.
no code implementations • 9 Mar 2024 • Rui Yang, Haoran Liu, Edison Marrese-Taylor, Qingcheng Zeng, Yu He Ke, Wanxin Li, Lechao Cheng, Qingyu Chen, James Caverlee, Yutaka Matsuo, Irene Li
Large Language Models (LLMs) have significantly advanced healthcare innovation on generation capabilities.
no code implementations • 22 Feb 2024 • Zhiyuan Wang, Jinhao Duan, Chenxi Yuan, Qingyu Chen, Tianlong Chen, Huaxiu Yao, Yue Zhang, Ren Wang, Kaidi Xu, Xiaoshuang Shi
Uncertainty estimation plays a pivotal role in ensuring the reliability of safety-critical human-AI interaction systems, particularly in the medical domain.
no code implementations • 20 Feb 2024 • Qiao Jin, Zhizheng Wang, Yifan Yang, Qingqing Zhu, Donald Wright, Thomas Huang, W John Wilbur, Zhe He, Andrew Taylor, Qingyu Chen, Zhiyong Lu
Clinical calculators play a vital role in healthcare by offering accurate evidence-based predictions for various purposes such as prognosis.
1 code implementation • 20 Feb 2024 • Qianqian Xie, Qingyu Chen, Aokun Chen, Cheng Peng, Yan Hu, Fongci Lin, Xueqing Peng, Jimin Huang, Jeffrey Zhang, Vipina Keloth, Xinyu Zhou, Huan He, Lucila Ohno-Machado, Yonghui Wu, Hua Xu, Jiang Bian
In response to this challenge, this study introduces Me-LLaMA, a novel medical LLM family that includes foundation models - Me-LLaMA 13/70B, along with their chat-enhanced versions - Me-LLaMA 13/70B-chat, developed through continual pre-training and instruction tuning of LLaMA2 using large medical datasets.
no code implementations • 19 Jan 2024 • Chih-Hsuan Wei, Alexis Allot, Po-Ting Lai, Robert Leaman, Shubo Tian, Ling Luo, Qiao Jin, Zhizheng Wang, Qingyu Chen, Zhiyong Lu
PubTator 3. 0 (https://www. ncbi. nlm. nih. gov/research/pubtator3/) is a biomedical literature resource using state-of-the-art AI techniques to offer semantic and relation searches for key concepts like proteins, genetic variants, diseases, and chemicals.
3 code implementations • 28 Nov 2023 • Rui Yang, Qingcheng Zeng, Keen You, Yujie Qiao, Lucas Huang, Chia-Chun Hsieh, Benjamin Rosand, Jeremy Goldwasser, Amisha D Dave, Tiarnan D. L. Keenan, Emily Y Chew, Dragomir Radev, Zhiyong Lu, Hua Xu, Qingyu Chen, Irene Li
This study introduces Ascle, a pioneering natural language processing (NLP) toolkit designed for medical text generation.
no code implementations • 4 Oct 2023 • Rui Yang, Edison Marrese-Taylor, Yuhe Ke, Lechao Cheng, Qingyu Chen, Irene Li
Our research demonstrates the effectiveness of using UMLS-augmented LLMs and highlights the potential application value of LLMs in in medical question-answering.
2 code implementations • 2 Jul 2023 • Qiao Jin, Won Kim, Qingyu Chen, Donald C. Comeau, Lana Yeganova, W. John Wilbur, Zhiyong Lu
In response, we introduce MedCPT, a first-of-its-kind Contrastively Pre-trained Transformer model for zero-shot semantic IR in biomedicine.
1 code implementation • 19 Jun 2023 • Po-Ting Lai, Chih-Hsuan Wei, Ling Luo, Qingyu Chen, Zhiyong Lu
State-of-the-art methods were used primarily to train machine learning models on individual RE datasets, such as protein-protein interaction and chemical-induced disease relation.
no code implementations • 15 Jun 2023 • Shubo Tian, Qiao Jin, Lana Yeganova, Po-Ting Lai, Qingqing Zhu, Xiuying Chen, Yifan Yang, Qingyu Chen, Won Kim, Donald C. Comeau, Rezarta Islamaj, Aadit Kapoor, Xin Gao, Zhiyong Lu
In this work, we examine the diverse applications of large language models (LLMs), such as ChatGPT, in biomedicine and health.
1 code implementation • 10 May 2023 • Qingyu Chen, Jingcheng Du, Yan Hu, Vipina Kuttichi Keloth, Xueqing Peng, Kalpana Raja, Rui Zhang, Zhiyong Lu, Hua Xu
Biomedical literature is growing rapidly, making it challenging to curate and extract knowledge manually.
1 code implementation • 19 Apr 2023 • Qiao Jin, Yifan Yang, Qingyu Chen, Zhiyong Lu
In this paper, we present GeneGPT, a novel method for teaching LLMs to use the Web APIs of the National Center for Biotechnology Information (NCBI) for answering genomics questions.
1 code implementation • 29 Mar 2023 • Yan Hu, Qingyu Chen, Jingcheng Du, Xueqing Peng, Vipina Kuttichi Keloth, Xu Zuo, Yujia Zhou, Zehan Li, Xiaoqian Jiang, Zhiyong Lu, Kirk Roberts, Hua Xu
Results: Using baseline prompts, GPT-3. 5 and GPT-4 achieved relaxed F1 scores of 0. 634, 0. 804 for MTSamples, and 0. 301, 0. 593 for VAERS.
no code implementations • 19 Feb 2023 • Xinyue Hu, Lin Gu, Kazuma Kobayashi, Qiyuan An, Qingyu Chen, Zhiyong Lu, Chang Su, Tatsuya Harada, Yingying Zhu
Medical visual question answering (VQA) aims to answer clinically relevant questions regarding input medical images.
1 code implementation • 3 Feb 2023 • Li Fang, Qingyu Chen, Chih-Hsuan Wei, Zhiyong Lu, Kai Wang
We thoroughly evaluated the performance of Bioformer as well as existing biomedical BERT models including BioBERT and PubMedBERT on 15 benchmark datasets of four different biomedical NLP tasks: named entity recognition, relation extraction, question answering and document classification.
1 code implementation • 30 Nov 2022 • Ling Luo, Chih-Hsuan Wei, Po-Ting Lai, Robert Leaman, Qingyu Chen, Zhiyong Lu
Biomedical named entity recognition (BioNER) seeks to automatically recognize biomedical entities in natural language text, serving as a necessary foundation for downstream text mining tasks and applications such as information extraction and question answering.
no code implementations • 27 Sep 2022 • Qingyu Chen, Alexis Allot, Robert Leaman, Chih-Hsuan Wei, Elaheh Aghaarabi, John J. Guerrerio, Lilly Xu, Zhiyong Lu
LitCovid (https://www. ncbi. nlm. nih. gov/research/coronavirus/), first launched in February 2020, is a first-of-its-kind literature hub for tracking up-to-date published research on COVID-19.
no code implementations • 16 Sep 2022 • Robert Leaman, Rezarta Islamaj, Alexis Allot, Qingyu Chen, W. John Wilbur, Zhiyong Lu
A significant percentage of COVID-19 survivors experience ongoing multisystemic symptoms that often affect daily living, a condition known as Long Covid or post-acute-sequelae of SARS-CoV-2 infection.
1 code implementation • 8 May 2022 • Ling Luo, Chih-Hsuan Wei, Po-Ting Lai, Qingyu Chen, Rezarta Islamaj Doğan, Zhiyong Lu
The automatic assignment of species information to the corresponding genes in a research article is a critically important step in the gene normalization task, whereby a gene mention is normalized and linked to a database record or identifier by a text-mining algorithm.
no code implementations • 20 Apr 2022 • Qingyu Chen, Alexis Allot, Robert Leaman, Rezarta Islamaj Doğan, Jingcheng Du, Li Fang, Kai Wang, Shuo Xu, Yuefu Zhang, Parsa Bagherzadeh, Sabine Bergler, Aakash Bhatnagar, Nidhir Bhavsar, Yung-Chun Chang, Sheng-Jie Lin, Wentai Tang, Hongtong Zhang, Ilija Tavchioski, Senja Pollak, Shubo Tian, Jinfeng Zhang, Yulia Otmakhova, Antonio Jimeno Yepes, Hang Dong, Honghan Wu, Richard Dufour, Yanis Labrak, Niladri Chatterjee, Kushagri Tandon, Fréjus Laleye, Loïc Rakotoson, Emmanuele Chersoni, Jinghang Gu, Annemarie Friedrich, Subhash Chandra Pujari, Mariia Chizhikova, Naveen Sivadasan, Zhiyong Lu
To close the gap, we organized the BioCreative LitCovid track to call for a community effort to tackle automated topic annotation for COVID-19 literature.
1 code implementation • 19 Apr 2022 • Qingyu Chen, Jingcheng Du, Alexis Allot, Zhiyong Lu
However, it has been a primary curation bottleneck due to the nature of the task and the rapid literature growth.
no code implementations • 18 Jan 2022 • Qiyuan An, Ruijiang Li, Lin Gu, Hao Zhang, Qingyu Chen, Zhiyong Lu, Fei Wang, Yingying Zhu
To evaluate our proposed method's utility and privacy loss, we apply our model on a medical report disease label classification task using two noisy challenging clinical text datasets.
no code implementations • 9 Nov 2020 • Qingyu Chen, Tiarnan D. L. Keenan, Alexis Allot, Yifan Peng, Elvira Agrón, Amitha Domalpally, Caroline C. W. Klaver, Daniel T. Luttikhuizen, Marcus H. Colyer, Catherine A. Cukras, Henry E. Wiley, M. Teresa Magone, Chantal Cousineau-Krieger, Wai T. Wong, Yingying Zhu, Emily Y. Chew, Zhiyong Lu
The objective was to develop and evaluate the performance of a novel 'M3' deep learning framework on RPD detection.
no code implementations • 9 Oct 2020 • Qingyu Chen, Robert Leaman, Alexis Allot, Ling Luo, Chih-Hsuan Wei, Shankai Yan, Zhiyong Lu
The COVID-19 pandemic has had a significant impact on society, both because of the serious health effects of COVID-19 and because of public health measures implemented to slow its spread.
no code implementations • 7 Aug 2020 • Lana Yeganova, Rezarta Islamaj, Qingyu Chen, Robert Leaman, Alexis Allot, Chin-Hsuan Wei, Donald C. Comeau, Won Kim, Yifan Peng, W. John Wilbur, Zhiyong Lu
In this study we analyze the LitCovid collection, 13, 369 COVID-19 related articles found in PubMed as of May 15th, 2020 with the purpose of examining the landscape of literature and presenting it in a format that facilitates information navigation and understanding.
no code implementations • 19 Jul 2020 • Yifan Peng, Tiarnan D. Keenan, Qingyu Chen, Elvira Agrón, Alexis Allot, Wai T. Wong, Emily Y. Chew, Zhiyong Lu
By 2040, age-related macular degeneration (AMD) will affect approximately 288 million people worldwide.
1 code implementation • WS 2020 • Yifan Peng, Qingyu Chen, Zhiyong Lu
Multi-task learning (MTL) has achieved remarkable success in natural language processing applications.
1 code implementation • 23 Dec 2019 • Qingyu Chen, Kyubum Lee, Shankai Yan, Sun Kim, Chih-Hsuan Wei, Zhiyong Lu
Capturing the semantics of related biological concepts, such as genes and mutations, is of significant importance to many research tasks in computational biology such as protein-protein interaction detection, gene-drug association prediction, and biomedical literature-based discovery.
no code implementations • 6 Sep 2019 • Qingyu Chen, Jingcheng Du, Sun Kim, W. John Wilbur, Zhiyong Lu
For the post challenge, the performance of both Random Forest and the Encoder Network was improved; in particular, the correlation of the Encoder Network was improved by ~13%.
1 code implementation • 7 Jun 2019 • Tiarnan D. Keenan, Shazia Dharssi, Yifan Peng, Qingyu Chen, Elvira Agrón, Wai T. Wong, Zhiyong Lu, Emily Y. Chew
Results: The deep learning models (GA detection, CGA detection from all eyes, and centrality detection from GA eyes) had AUC of 0. 933-0. 976, 0. 939-0. 976, and 0. 827-0. 888, respectively.
no code implementations • 2 Dec 2018 • Qingyu Chen, Yifan Peng, Tiarnan Keenan, Shazia Dharssi, Elvira Agron, Wai T. Wong, Emily Y. Chew, Zhiyong Lu
Built on our previous work DeepSeeNet, we developed a novel deep learning model for automated classification of images into the 9-step scale.
Age-Related Macular Degeneration Classification Classification +2
1 code implementation • 19 Nov 2018 • Yifan Peng, Shazia Dharssi, Qingyu Chen, Tiarnan D. Keenan, Elvira Agrón, Wai T. Wong, Emily Y. Chew, Zhiyong Lu
DeepSeeNet simulates the human grading process by first detecting individual AMD risk factors (drusen size, pigmentary abnormalities) for each eye and then calculating a patient-based AMD severity score using the AREDS Simplified Severity Scale.
4 code implementations • 13 Nov 2018 • Jingcheng Du, Qingyu Chen, Yifan Peng, Yang Xiang, Cui Tao, Zhiyong Lu
Due to this nature, the multi-label text classification task is often considered to be more challenging compared to the binary or multi-class text classification problems.
4 code implementations • 22 Oct 2018 • Qingyu Chen, Yifan Peng, Zhiyong Lu
Sentence embeddings have become an essential part of today's natural language processing (NLP) systems, especially together advanced deep learning methods.
Ranked #1 on Sentence Embeddings For Biomedical Texts on MedSTS (using extra training data)