Search Results for author: Shan E Ahmed Raza

Found 27 papers, 6 papers with code

An Automated Pipeline for Tumour-Infiltrating Lymphocyte Scoring in Breast Cancer

1 code implementation10 Nov 2023 Adam J Shephard, Mostafa Jahanifar, Ruoyu Wang, Muhammad Dawood, Simon Graham, Kastytis Sidlauskas, Syed Ali Khurram, Nasir M Rajpoot, Shan E Ahmed Raza

Tumour-infiltrating lymphocytes (TILs) are considered as a valuable prognostic markers in both triple-negative and human epidermal growth factor receptor 2 (HER2) positive breast cancer.

whole slide images

Domain Generalization in Computational Pathology: Survey and Guidelines

no code implementations30 Oct 2023 Mostafa Jahanifar, Manahil Raza, Kesi Xu, Trinh Vuong, Rob Jewsbury, Adam Shephard, Neda Zamanitajeddin, Jin Tae Kwak, Shan E Ahmed Raza, Fayyaz Minhas, Nasir Rajpoot

Deep learning models have exhibited exceptional effectiveness in Computational Pathology (CPath) by tackling intricate tasks across an array of histology image analysis applications.

Benchmarking Domain Generalization

A Fully Automated and Explainable Algorithm for the Prediction of Malignant Transformation in Oral Epithelial Dysplasia

no code implementations6 Jul 2023 Adam J Shephard, Raja Muhammad Saad Bashir, Hanya Mahmood, Mostafa Jahanifar, Fayyaz Minhas, Shan E Ahmed Raza, Kris D McCombe, Stephanie G Craig, Jacqueline James, Jill Brooks, Paul Nankivell, Hisham Mehanna, Syed Ali Khurram, Nasir M Rajpoot

To address this, we developed a novel artificial intelligence algorithm that can assign an Oral Malignant Transformation (OMT) risk score, based on histological patterns in the in Haematoxylin and Eosin stained whole slide images, to quantify the risk of OED progression.

whole slide images

CoNIC Challenge: Pushing the Frontiers of Nuclear Detection, Segmentation, Classification and Counting

1 code implementation11 Mar 2023 Simon Graham, Quoc Dang Vu, Mostafa Jahanifar, Martin Weigert, Uwe Schmidt, Wenhua Zhang, Jun Zhang, Sen yang, Jinxi Xiang, Xiyue Wang, Josef Lorenz Rumberger, Elias Baumann, Peter Hirsch, Lihao Liu, Chenyang Hong, Angelica I. Aviles-Rivero, Ayushi Jain, Heeyoung Ahn, Yiyu Hong, Hussam Azzuni, Min Xu, Mohammad Yaqub, Marie-Claire Blache, Benoît Piégu, Bertrand Vernay, Tim Scherr, Moritz Böhland, Katharina Löffler, Jiachen Li, Weiqin Ying, Chixin Wang, Dagmar Kainmueller, Carola-Bibiane Schönlieb, Shuolin Liu, Dhairya Talsania, Yughender Meda, Prakash Mishra, Muhammad Ridzuan, Oliver Neumann, Marcel P. Schilling, Markus Reischl, Ralf Mikut, Banban Huang, Hsiang-Chin Chien, Ching-Ping Wang, Chia-Yen Lee, Hong-Kun Lin, Zaiyi Liu, Xipeng Pan, Chu Han, Jijun Cheng, Muhammad Dawood, Srijay Deshpande, Raja Muhammad Saad Bashir, Adam Shephard, Pedro Costa, João D. Nunes, Aurélio Campilho, Jaime S. Cardoso, Hrishikesh P S, Densen Puthussery, Devika R G, Jiji C V, Ye Zhang, Zijie Fang, Zhifan Lin, Yongbing Zhang, Chunhui Lin, Liukun Zhang, Lijian Mao, Min Wu, Vi Thi-Tuong Vo, Soo-Hyung Kim, Taebum Lee, Satoshi Kondo, Satoshi Kasai, Pranay Dumbhare, Vedant Phuse, Yash Dubey, Ankush Jamthikar, Trinh Thi Le Vuong, Jin Tae Kwak, Dorsa Ziaei, Hyun Jung, Tianyi Miao, David Snead, Shan E Ahmed Raza, Fayyaz Minhas, Nasir M. Rajpoot

Nuclear detection, segmentation and morphometric profiling are essential in helping us further understand the relationship between histology and patient outcome.

Nuclear Segmentation Segmentation +2

Consistency Regularisation in Varying Contexts and Feature Perturbations for Semi-Supervised Semantic Segmentation of Histology Images

no code implementations30 Jan 2023 Raja Muhammad Saad Bashir, Talha Qaiser, Shan E Ahmed Raza, Nasir M. Rajpoot

The proposed method incorporates context-aware consistency by contrasting pairs of overlapping images in a pixel-wise manner from changing contexts resulting in robust and context invariant features.

Semi-Supervised Semantic Segmentation

LYSTO: The Lymphocyte Assessment Hackathon and Benchmark Dataset

no code implementations16 Jan 2023 Yiping Jiao, Jeroen van der Laak, Shadi Albarqouni, Zhang Li, Tao Tan, Abhir Bhalerao, Jiabo Ma, Jiamei Sun, Johnathan Pocock, Josien P. W. Pluim, Navid Alemi Koohbanani, Raja Muhammad Saad Bashir, Shan E Ahmed Raza, Sibo Liu, Simon Graham, Suzanne Wetstein, Syed Ali Khurram, Thomas Watson, Nasir Rajpoot, Mitko Veta, Francesco Ciompi

Additionally, we present post-competition results where we show how the presented methods perform on an independent set of lung cancer slides, which was not part of the initial competition, as well as a comparison on lymphocyte assessment between presented methods and a panel of pathologists.

Nuclear Segmentation and Classification: On Color & Compression Generalization

no code implementations9 Jan 2023 Quoc Dang Vu, Robert Jewsbury, Simon Graham, Mostafa Jahanifar, Shan E Ahmed Raza, Fayyaz Minhas, Abhir Bhalerao, Nasir Rajpoot

Since the introduction of digital and computational pathology as a field, one of the major problems in the clinical application of algorithms has been the struggle to generalize well to examples outside the distribution of the training data.

Classification Nuclear Segmentation +1

TIAger: Tumor-Infiltrating Lymphocyte Scoring in Breast Cancer for the TiGER Challenge

1 code implementation23 Jun 2022 Adam Shephard, Mostafa Jahanifar, Ruoyu Wang, Muhammad Dawood, Simon Graham, Kastytis Sidlauskas, Syed Ali Khurram, Nasir Rajpoot, Shan E Ahmed Raza

The Tumor InfiltratinG lymphocytes in breast cancER (TiGER) challenge, aims to assess the prognostic significance of computer-generated TILs scores for predicting survival as part of a Cox proportional hazards model.

One Model is All You Need: Multi-Task Learning Enables Simultaneous Histology Image Segmentation and Classification

1 code implementation28 Feb 2022 Simon Graham, Quoc Dang Vu, Mostafa Jahanifar, Shan E Ahmed Raza, Fayyaz Minhas, David Snead, Nasir Rajpoot

In this paper, we present a multi-task learning approach for segmentation and classification of nuclei, glands, lumina and different tissue regions that leverages data from multiple independent data sources.

Cell Detection Explainable Models +4

Deep Learning based Prediction of MSI using MMR Markers in Colorectal Cancer

no code implementations24 Feb 2022 Ruqayya Awan, Mohammed Nimir, Shan E Ahmed Raza, Mohsin Bilal, Johannes Lotz, David Snead, Andrew Robinson, Nasir Rajpoot

Unlike previous studies on MSI prediction involving training a CNN using coarse labels (MSI vs Microsatellite Stable (MSS)), we have utilised fine-grain MMR labels for training purposes.

Deep Feature based Cross-slide Registration

no code implementations21 Feb 2022 Ruqayya Awan, Shan E Ahmed Raza, Johannes Lotz, Nick Weiss, Nasir Rajpoot

During the slide preparation, a tissue section may be placed at an arbitrary orientation as compared to other sections of the same tissue block.

Handcrafted Histological Transformer (H2T): Unsupervised Representation of Whole Slide Images

1 code implementation14 Feb 2022 Quoc Dang Vu, Kashif Rajpoot, Shan E Ahmed Raza, Nasir Rajpoot

Based on our experiments involving various datasets consisting of a total of 5, 306 WSIs, the results demonstrate that H2T based holistic WSI-level representations offer competitive performance compared to recent state-of-the-art methods and can be readily utilized for various downstream analysis tasks.

Decision Making whole slide images

CoNIC: Colon Nuclei Identification and Counting Challenge 2022

no code implementations29 Nov 2021 Simon Graham, Mostafa Jahanifar, Quoc Dang Vu, Giorgos Hadjigeorghiou, Thomas Leech, David Snead, Shan E Ahmed Raza, Fayyaz Minhas, Nasir Rajpoot

The challenge encourages researchers to develop algorithms that perform segmentation, classification and counting of nuclei within the current largest known publicly available nuclei-level dataset in CPath, containing around half a million labelled nuclei.

Explainable Models Nuclear Segmentation

A digital score of tumour-associated stroma infiltrating lymphocytes predicts survival in head and neck squamous cell carcinoma

no code implementations16 Apr 2021 Muhammad Shaban, Shan E Ahmed Raza, Mariam Hassan, Arif Jamshed, Sajid Mushtaq, Asif Loya, Nikolaos Batis, Jill Brooks, Paul Nankivell, Neil Sharma, Max Robinson, Hisham Mehanna, Syed Ali Khurram, Nasir Rajpoot

In this study, our aim is to explore the prognostic significance of tumour-associated stroma infiltrating lymphocytes (TASILs) in head and neck squamous cell carcinoma (HNSCC) through an AI based automated method.

Clinical Knowledge whole slide images

HydraMix-Net: A Deep Multi-task Semi-supervised Learning Approach for Cell Detection and Classification

no code implementations11 Aug 2020 R. M. Saad Bashir, Talha Qaiser, Shan E Ahmed Raza, Nasir M. Rajpoot

The model is trained in multi-task learning manner with noise tolerant joint loss for classification localization and achieves better performance when given limited data in contrast to a simple deep model.

Cell Detection General Classification +1

DeepSDCS: Dissecting cancer proliferation heterogeneity in Ki67 digital whole slide images

no code implementations28 Jun 2018 Priya Lakshmi Narayanan, Shan E Ahmed Raza, Andrew Dodson, Barry Gusterson, Mitchell Dowsett, Yinyin Yuan

Subsequently, seeds generated from cell segmentation were propagated to a spatially constrained convolutional neural network for the classification of the cells into stromal, lymphocyte, Ki67-positive cancer cell, and Ki67-negative cancer cell.

Cell Segmentation General Classification +2

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