Search Results for author: Bennett A. Landman

Found 94 papers, 34 papers with code

Unsupervised Discovery of Clinical Disease Signatures Using Probabilistic Independence

no code implementations8 Feb 2024 Thomas A. Lasko, John M. Still, Thomas Z. Li, Marco Barbero Mota, William W. Stead, Eric V. Strobl, Bennett A. Landman, Fabien Maldonado

Insufficiently precise diagnosis of clinical disease is likely responsible for many treatment failures, even for common conditions and treatments.

RAISE -- Radiology AI Safety, an End-to-end lifecycle approach

no code implementations24 Nov 2023 M. Jorge Cardoso, Julia Moosbauer, Tessa S. Cook, B. Selnur Erdal, Brad Genereaux, Vikash Gupta, Bennett A. Landman, Tiarna Lee, Parashkev Nachev, Elanchezhian Somasundaram, Ronald M. Summers, Khaled Younis, Sebastien Ourselin, Franz MJ Pfister

The integration of AI into radiology introduces opportunities for improved clinical care provision and efficiency but it demands a meticulous approach to mitigate potential risks as with any other new technology.

Fairness Scheduling

DeformUX-Net: Exploring a 3D Foundation Backbone for Medical Image Segmentation with Depthwise Deformable Convolution

1 code implementation30 Sep 2023 Ho Hin Lee, Quan Liu, Qi Yang, Xin Yu, Shunxing Bao, Yuankai Huo, Bennett A. Landman

We hypothesize that deformable convolution can be an exploratory alternative to combine all advantages from the previous operators, providing long-range dependency, adaptive spatial aggregation and computational efficiency as a foundation backbone.

Computational Efficiency Image Segmentation +2

Inter-vendor harmonization of Computed Tomography (CT) reconstruction kernels using unpaired image translation

no code implementations22 Sep 2023 Aravind R. Krishnan, Kaiwen Xu, Thomas Li, Chenyu Gao, Lucas W. Remedios, Praitayini Kanakaraj, Ho Hin Lee, Shunxing Bao, Kim L. Sandler, Fabien Maldonado, Ivana Isgum, Bennett A. Landman

In this study, we adopt an unpaired image translation approach to investigate harmonization between and across reconstruction kernels from different manufacturers by constructing a multipath cycle generative adversarial network (GAN).

Computed Tomography (CT) Generative Adversarial Network

Deep conditional generative models for longitudinal single-slice abdominal computed tomography harmonization

1 code implementation17 Sep 2023 Xin Yu, Qi Yang, Yucheng Tang, Riqiang Gao, Shunxing Bao, Leon Y. Cai, Ho Hin Lee, Yuankai Huo, Ann Zenobia Moore, Luigi Ferrucci, Bennett A. Landman

We further evaluate our method's capability to harmonize longitudinal positional variation on 1033 subjects from the Baltimore Longitudinal Study of Aging (BLSA) dataset, which contains longitudinal single abdominal slices, and confirmed that our method can harmonize the slice positional variance in terms of visceral fat area.

Computed Tomography (CT)

Enhancing Hierarchical Transformers for Whole Brain Segmentation with Intracranial Measurements Integration

1 code implementation8 Sep 2023 Xin Yu, Yucheng Tang, Qi Yang, Ho Hin Lee, Shunxing Bao, Yuankai Huo, Bennett A. Landman

Subsequently, the model is finetuned with 45 T1w 3D volumes from Open Access Series Imaging Studies (OASIS) where both 133 whole brain classes and TICV/PFV labels are available.

Brain Segmentation Segmentation

Feasibility of Universal Anomaly Detection without Knowing the Abnormality in Medical Images

no code implementations3 Jul 2023 Can Cui, Yaohong Wang, Shunxing Bao, Yucheng Tang, Ruining Deng, Lucas W. Remedios, Zuhayr Asad, Joseph T. Roland, Ken S. Lau, Qi Liu, Lori A. Coburn, Keith T. Wilson, Bennett A. Landman, Yuankai Huo

Many anomaly detection approaches, especially deep learning methods, have been recently developed to identify abnormal image morphology by only employing normal images during training.

Anomaly Detection

Multi-Contrast Computed Tomography Atlas of Healthy Pancreas

no code implementations2 Jun 2023 Yinchi Zhou, Ho Hin Lee, Yucheng Tang, Xin Yu, Qi Yang, Shunxing Bao, Jeffrey M. Spraggins, Yuankai Huo, Bennett A. Landman

Briefly, DEEDs affine and non-rigid registration are performed to transfer patient abdominal volumes to a fixed high-resolution atlas template.

Anatomy Computed Tomography (CT)

Exploring shared memory architectures for end-to-end gigapixel deep learning

no code implementations24 Apr 2023 Lucas W. Remedios, Leon Y. Cai, Samuel W. Remedios, Karthik Ramadass, Aravind Krishnan, Ruining Deng, Can Cui, Shunxing Bao, Lori A. Coburn, Yuankai Huo, Bennett A. Landman

The M1 Ultra SoC was able to train the model directly on gigapixel images (16000$\times$64000 pixels, 1. 024 billion pixels) with a batch size of 1 using over 100 GB of unified memory for the process at an average speed of 1 minute and 21 seconds per batch with Tensorflow 2/Keras.

whole slide images

Zero-shot CT Field-of-view Completion with Unconditional Generative Diffusion Prior

no code implementations7 Apr 2023 Kaiwen Xu, Aravind R. Krishnan, Thomas Z. Li, Yuankai Huo, Kim L. Sandler, Fabien Maldonado, Bennett A. Landman

Anatomically consistent field-of-view (FOV) completion to recover truncated body sections has important applications in quantitative analyses of computed tomography (CT) with limited FOV.

Computed Tomography (CT)

A Unified Learning Model for Estimating Fiber Orientation Distribution Functions on Heterogeneous Multi-shell Diffusion-weighted MRI

no code implementations29 Mar 2023 Tianyuan Yao, Nancy Newlin, Praitayini Kanakaraj, Vishwesh Nath, Leon Y Cai, Karthik Ramadass, Kurt Schilling, Bennett A. Landman, Yuankai Huo

Diffusion-weighted (DW) MRI measures the direction and scale of the local diffusion process in every voxel through its spectrum in q-space, typically acquired in one or more shells.

Understanding metric-related pitfalls in image analysis validation

no code implementations3 Feb 2023 Annika Reinke, Minu D. Tizabi, Michael Baumgartner, Matthias Eisenmann, Doreen Heckmann-Nötzel, A. Emre Kavur, Tim Rädsch, Carole H. Sudre, Laura Acion, Michela Antonelli, Tal Arbel, Spyridon Bakas, Arriel Benis, Matthew Blaschko, Florian Buettner, M. Jorge Cardoso, Veronika Cheplygina, Jianxu Chen, Evangelia Christodoulou, Beth A. Cimini, Gary S. Collins, Keyvan Farahani, Luciana Ferrer, Adrian Galdran, Bram van Ginneken, Ben Glocker, Patrick Godau, Robert Haase, Daniel A. Hashimoto, Michael M. Hoffman, Merel Huisman, Fabian Isensee, Pierre Jannin, Charles E. Kahn, Dagmar Kainmueller, Bernhard Kainz, Alexandros Karargyris, Alan Karthikesalingam, Hannes Kenngott, Jens Kleesiek, Florian Kofler, Thijs Kooi, Annette Kopp-Schneider, Michal Kozubek, Anna Kreshuk, Tahsin Kurc, Bennett A. Landman, Geert Litjens, Amin Madani, Klaus Maier-Hein, Anne L. Martel, Peter Mattson, Erik Meijering, Bjoern Menze, Karel G. M. Moons, Henning Müller, Brennan Nichyporuk, Felix Nickel, Jens Petersen, Susanne M. Rafelski, Nasir Rajpoot, Mauricio Reyes, Michael A. Riegler, Nicola Rieke, Julio Saez-Rodriguez, Clara I. Sánchez, Shravya Shetty, Maarten van Smeden, Ronald M. Summers, Abdel A. Taha, Aleksei Tiulpin, Sotirios A. Tsaftaris, Ben van Calster, Gaël Varoquaux, Manuel Wiesenfarth, Ziv R. Yaniv, Paul F. Jäger, Lena Maier-Hein

Validation metrics are key for the reliable tracking of scientific progress and for bridging the current chasm between artificial intelligence (AI) research and its translation into practice.

CLIP-Driven Universal Model for Organ Segmentation and Tumor Detection

2 code implementations ICCV 2023 Jie Liu, Yixiao Zhang, Jie-Neng Chen, Junfei Xiao, Yongyi Lu, Bennett A. Landman, Yixuan Yuan, Alan Yuille, Yucheng Tang, Zongwei Zhou

The proposed model is developed from an assembly of 14 datasets, using a total of 3, 410 CT scans for training and then evaluated on 6, 162 external CT scans from 3 additional datasets.

Organ Segmentation Segmentation +1

Single Slice Thigh CT Muscle Group Segmentation with Domain Adaptation and Self-Training

1 code implementation30 Nov 2022 Qi Yang, Xin Yu, Ho Hin Lee, Leon Y. Cai, Kaiwen Xu, Shunxing Bao, Yuankai Huo, Ann Zenobia Moore, Sokratis Makrogiannis, Luigi Ferrucci, Bennett A. Landman

The proposed pipeline is effective and robust in extracting muscle groups on 2D single slice CT thigh images. The container is available for public use at https://github. com/MASILab/DA_CT_muscle_seg

Anatomy Computed Tomography (CT) +1

Adaptive Contrastive Learning with Dynamic Correlation for Multi-Phase Organ Segmentation

1 code implementation16 Oct 2022 Ho Hin Lee, Yucheng Tang, Han Liu, Yubo Fan, Leon Y. Cai, Qi Yang, Xin Yu, Shunxing Bao, Yuankai Huo, Bennett A. Landman

We evaluate our proposed approach on multi-organ segmentation with both non-contrast CT (NCCT) datasets and the MICCAI 2015 BTCV Challenge contrast-enhance CT (CECT) datasets.

Computed Tomography (CT) Contrastive Learning +1

3D UX-Net: A Large Kernel Volumetric ConvNet Modernizing Hierarchical Transformer for Medical Image Segmentation

2 code implementations29 Sep 2022 Ho Hin Lee, Shunxing Bao, Yuankai Huo, Bennett A. Landman

Hierarchical transformers (e. g., Swin Transformers) reintroduced several ConvNet priors and further enhanced the practical viability of adapting volumetric segmentation in 3D medical datasets.

Image Segmentation Medical Image Segmentation +3

Longitudinal Variability Analysis on Low-dose Abdominal CT with Deep Learning-based Segmentation

no code implementations28 Sep 2022 Xin Yu, Yucheng Tang, Qi Yang, Ho Hin Lee, Riqiang Gao, Shunxing Bao, Ann Zenobia Moore, Luigi Ferrucci, Bennett A. Landman

Metabolic health is increasingly implicated as a risk factor across conditions from cardiology to neurology, and efficiency assessment of body composition is critical to quantitatively characterizing these relationships.

Computed Tomography (CT) Segmentation

Reducing Positional Variance in Cross-sectional Abdominal CT Slices with Deep Conditional Generative Models

1 code implementation28 Sep 2022 Xin Yu, Qi Yang, Yucheng Tang, Riqiang Gao, Shunxing Bao, LeonY. Cai, Ho Hin Lee, Yuankai Huo, Ann Zenobia Moore, Luigi Ferrucci, Bennett A. Landman

External experiments on 20 subjects from the Baltimore Longitudinal Study of Aging (BLSA) dataset that contains longitudinal single abdominal slices validate that our method can harmonize the slice positional variance in terms of muscle and visceral fat area.

Computed Tomography (CT)

UNesT: Local Spatial Representation Learning with Hierarchical Transformer for Efficient Medical Segmentation

1 code implementation28 Sep 2022 Xin Yu, Qi Yang, Yinchi Zhou, Leon Y. Cai, Riqiang Gao, Ho Hin Lee, Thomas Li, Shunxing Bao, Zhoubing Xu, Thomas A. Lasko, Richard G. Abramson, Zizhao Zhang, Yuankai Huo, Bennett A. Landman, Yucheng Tang

Transformer-based models, capable of learning better global dependencies, have recently demonstrated exceptional representation learning capabilities in computer vision and medical image analysis.

Brain Segmentation Image Segmentation +3

Time-distance vision transformers in lung cancer diagnosis from longitudinal computed tomography

1 code implementation4 Sep 2022 Thomas Z. Li, Kaiwen Xu, Riqiang Gao, Yucheng Tang, Thomas A. Lasko, Fabien Maldonado, Kim Sandler, Bennett A. Landman

In cross-validation on screening chest CTs from the NLST, our methods (0. 785 and 0. 786 AUC respectively) significantly outperform a cross-sectional approach (0. 734 AUC) and match the discriminative performance of the leading longitudinal medical imaging algorithm (0. 779 AUC) on benign versus malignant classification.

Lung Cancer Diagnosis Time Series Analysis

Compound Figure Separation of Biomedical Images: Mining Large Datasets for Self-supervised Learning

1 code implementation30 Aug 2022 Tianyuan Yao, Chang Qu, Jun Long, Quan Liu, Ruining Deng, Yuanhan Tian, Jiachen Xu, Aadarsh Jha, Zuhayr Asad, Shunxing Bao, Mengyang Zhao, Agnes B. Fogo, Bennett A. Landman, Haichun Yang, Catie Chang, Yuankai Huo

In order to extract and separate compound figures into usable individual images for downstream learning, we propose a simple compound figure separation (SimCFS) framework without using the traditionally required detection bounding box annotations, with a new loss function and a hard case simulation.

Contrastive Learning Image Augmentation +2

Cross-scale Attention Guided Multi-instance Learning for Crohn's Disease Diagnosis with Pathological Images

1 code implementation15 Aug 2022 Ruining Deng, Can Cui, Lucas W. Remedios, Shunxing Bao, R. Michael Womick, Sophie Chiron, Jia Li, Joseph T. Roland, Ken S. Lau, Qi Liu, Keith T. Wilson, Yaohong Wang, Lori A. Coburn, Bennett A. Landman, Yuankai Huo

Multi-instance learning (MIL) is widely used in the computer-aided interpretation of pathological Whole Slide Images (WSIs) to solve the lack of pixel-wise or patch-wise annotations.

whole slide images

Metrics reloaded: Recommendations for image analysis validation

1 code implementation3 Jun 2022 Lena Maier-Hein, Annika Reinke, Patrick Godau, Minu D. Tizabi, Florian Buettner, Evangelia Christodoulou, Ben Glocker, Fabian Isensee, Jens Kleesiek, Michal Kozubek, Mauricio Reyes, Michael A. Riegler, Manuel Wiesenfarth, A. Emre Kavur, Carole H. Sudre, Michael Baumgartner, Matthias Eisenmann, Doreen Heckmann-Nötzel, Tim Rädsch, Laura Acion, Michela Antonelli, Tal Arbel, Spyridon Bakas, Arriel Benis, Matthew Blaschko, M. Jorge Cardoso, Veronika Cheplygina, Beth A. Cimini, Gary S. Collins, Keyvan Farahani, Luciana Ferrer, Adrian Galdran, Bram van Ginneken, Robert Haase, Daniel A. Hashimoto, Michael M. Hoffman, Merel Huisman, Pierre Jannin, Charles E. Kahn, Dagmar Kainmueller, Bernhard Kainz, Alexandros Karargyris, Alan Karthikesalingam, Hannes Kenngott, Florian Kofler, Annette Kopp-Schneider, Anna Kreshuk, Tahsin Kurc, Bennett A. Landman, Geert Litjens, Amin Madani, Klaus Maier-Hein, Anne L. Martel, Peter Mattson, Erik Meijering, Bjoern Menze, Karel G. M. Moons, Henning Müller, Brennan Nichyporuk, Felix Nickel, Jens Petersen, Nasir Rajpoot, Nicola Rieke, Julio Saez-Rodriguez, Clara I. Sánchez, Shravya Shetty, Maarten van Smeden, Ronald M. Summers, Abdel A. Taha, Aleksei Tiulpin, Sotirios A. Tsaftaris, Ben van Calster, Gaël Varoquaux, Paul F. Jäger

The framework was developed in a multi-stage Delphi process and is based on the novel concept of a problem fingerprint - a structured representation of the given problem that captures all aspects that are relevant for metric selection, from the domain interest to the properties of the target structure(s), data set and algorithm output.

Instance Segmentation object-detection +2

Pseudo-Label Guided Multi-Contrast Generalization for Non-Contrast Organ-Aware Segmentation

no code implementations12 May 2022 Ho Hin Lee, Yucheng Tang, Riqiang Gao, Qi Yang, Xin Yu, Shunxing Bao, James G. Terry, J. Jeffrey Carr, Yuankai Huo, Bennett A. Landman

In this paper, we propose a novel unsupervised approach that leverages pairwise contrast-enhanced CT (CECT) context to compute non-contrast segmentation without ground-truth label.

Organ Segmentation Pseudo Label +1

Deep Multi-modal Fusion of Image and Non-image Data in Disease Diagnosis and Prognosis: A Review

no code implementations25 Mar 2022 Can Cui, Haichun Yang, Yaohong Wang, Shilin Zhao, Zuhayr Asad, Lori A. Coburn, Keith T. Wilson, Bennett A. Landman, Yuankai Huo

The rapid development of diagnostic technologies in healthcare is leading to higher requirements for physicians to handle and integrate the heterogeneous, yet complementary data that are produced during routine practice.

Decision Making

Survival Prediction of Brain Cancer with Incomplete Radiology, Pathology, Genomics, and Demographic Data

no code implementations8 Mar 2022 Can Cui, Han Liu, Quan Liu, Ruining Deng, Zuhayr Asad, Yaohong WangShilin Zhao, Haichun Yang, Bennett A. Landman, Yuankai Huo

Thus, there are still open questions on how to effectively predict brain cancer survival from the incomplete radiological, pathological, genomic, and demographic data (e. g., one or more modalities might not be collected for a patient).

Computational Efficiency Survival Prediction

Characterizing Renal Structures with 3D Block Aggregate Transformers

no code implementations4 Mar 2022 Xin Yu, Yucheng Tang, Yinchi Zhou, Riqiang Gao, Qi Yang, Ho Hin Lee, Thomas Li, Shunxing Bao, Yuankai Huo, Zhoubing Xu, Thomas A. Lasko, Richard G. Abramson, Bennett A. Landman

Efficiently quantifying renal structures can provide distinct spatial context and facilitate biomarker discovery for kidney morphology.

Circle Representation for Medical Object Detection

1 code implementation22 Oct 2021 Ethan H. Nguyen, Haichun Yang, Ruining Deng, Yuzhe Lu, Zheyu Zhu, Joseph T. Roland, Le Lu, Bennett A. Landman, Agnes B. Fogo, Yuankai Huo

Compared with the conventional bounding box representation, the proposed bounding circle representation innovates in three-fold: (1) it is optimized for ball-shaped biomedical objects; (2) The circle representation reduced the degree of freedom compared with box representation; (3) It is naturally more rotation invariant.

Medical Object Detection Object +1

You May Need both Good-GAN and Bad-GAN for Anomaly Detection

no code implementations29 Sep 2021 Riqiang Gao, Zhoubing Xu, Guillaume Chabin, Awais Mansoor, Florin-Cristian Ghesu, Bogdan Georgescu, Bennett A. Landman, Sasa Grbic

A Bad-GAN generates pseudo anomalies at the low-density area of inlier distribution, and thus the inlier/outlier distinction can be approximated.

Anatomy Anomaly Detection

Random Multi-Channel Image Synthesis for Multiplexed Immunofluorescence Imaging

no code implementations MICCAI Workshop COMPAY 2021 Shunxing Bao, Yucheng Tang, Ho Hin Lee, Riqiang Gao, Sophie Chiron, Ilwoo Lyu, Lori A. Coburn, Keith T. Wilson, Joseph T. Roland, Bennett A. Landman, Yuankai Huo

Our contribution is three-fold: (1) a single deep network framework is proposed to tackle missing stain in MxIF; (2) the proposed 'N-to-N' strategy reduces theoretical four years of computational time to 20 hours when covering all possible missing stains scenarios, with up to five missing stains (e. g., '(N-1)-to-1', '(N-2)-to-2'); and (3) this work is the first comprehensive experimental study of investigating cross-stain synthesis in MxIF.

Generative Adversarial Network Image Generation +1

Lung Cancer Risk Estimation with Incomplete Data: A Joint Missing Imputation Perspective

no code implementations25 Jul 2021 Riqiang Gao, Yucheng Tang, Kaiwen Xu, Ho Hin Lee, Steve Deppen, Kim Sandler, Pierre Massion, Thomas A. Lasko, Yuankai Huo, Bennett A. Landman

To our knowledge, it is the first generative adversarial model that addresses multi-modal missing imputation by modeling the joint distribution of image and non-image data.

Imputation

Compound Figure Separation of Biomedical Images with Side Loss

1 code implementation19 Jul 2021 Tianyuan Yao, Chang Qu, Quan Liu, Ruining Deng, Yuanhan Tian, Jiachen Xu, Aadarsh Jha, Shunxing Bao, Mengyang Zhao, Agnes B. Fogo, Bennett A. Landman, Catie Chang, Haichun Yang, Yuankai Huo

Our technical contribution is three-fold: (1) we introduce a new side loss that is designed for compound figure separation; (2) we introduce an intra-class image augmentation method to simulate hard cases; (3) the proposed framework enables an efficient deployment to new classes of images, without requiring resource extensive bounding box annotations.

Contrastive Learning Image Augmentation +1

Common Limitations of Image Processing Metrics: A Picture Story

1 code implementation12 Apr 2021 Annika Reinke, Minu D. Tizabi, Carole H. Sudre, Matthias Eisenmann, Tim Rädsch, Michael Baumgartner, Laura Acion, Michela Antonelli, Tal Arbel, Spyridon Bakas, Peter Bankhead, Arriel Benis, Matthew Blaschko, Florian Buettner, M. Jorge Cardoso, Jianxu Chen, Veronika Cheplygina, Evangelia Christodoulou, Beth Cimini, Gary S. Collins, Sandy Engelhardt, Keyvan Farahani, Luciana Ferrer, Adrian Galdran, Bram van Ginneken, Ben Glocker, Patrick Godau, Robert Haase, Fred Hamprecht, Daniel A. Hashimoto, Doreen Heckmann-Nötzel, Peter Hirsch, Michael M. Hoffman, Merel Huisman, Fabian Isensee, Pierre Jannin, Charles E. Kahn, Dagmar Kainmueller, Bernhard Kainz, Alexandros Karargyris, Alan Karthikesalingam, A. Emre Kavur, Hannes Kenngott, Jens Kleesiek, Andreas Kleppe, Sven Kohler, Florian Kofler, Annette Kopp-Schneider, Thijs Kooi, Michal Kozubek, Anna Kreshuk, Tahsin Kurc, Bennett A. Landman, Geert Litjens, Amin Madani, Klaus Maier-Hein, Anne L. Martel, Peter Mattson, Erik Meijering, Bjoern Menze, David Moher, Karel G. M. Moons, Henning Müller, Brennan Nichyporuk, Felix Nickel, M. Alican Noyan, Jens Petersen, Gorkem Polat, Susanne M. Rafelski, Nasir Rajpoot, Mauricio Reyes, Nicola Rieke, Michael Riegler, Hassan Rivaz, Julio Saez-Rodriguez, Clara I. Sánchez, Julien Schroeter, Anindo Saha, M. Alper Selver, Lalith Sharan, Shravya Shetty, Maarten van Smeden, Bram Stieltjes, Ronald M. Summers, Abdel A. Taha, Aleksei Tiulpin, Sotirios A. Tsaftaris, Ben van Calster, Gaël Varoquaux, Manuel Wiesenfarth, Ziv R. Yaniv, Paul Jäger, Lena Maier-Hein

While the importance of automatic image analysis is continuously increasing, recent meta-research revealed major flaws with respect to algorithm validation.

Instance Segmentation object-detection +2

Diminishing Uncertainty within the Training Pool: Active Learning for Medical Image Segmentation

no code implementations7 Jan 2021 Vishwesh Nath, Dong Yang, Bennett A. Landman, Daguang Xu, Holger R. Roth

The primary advantage being that active learning frameworks select data points that can accelerate the learning process of a model and can reduce the amount of data needed to achieve full accuracy as compared to a model trained on a randomly acquired data set.

Active Learning BIG-bench Machine Learning +4

RAP-Net: Coarse-to-Fine Multi-Organ Segmentation with Single Random Anatomical Prior

1 code implementation23 Dec 2020 Ho Hin Lee, Yucheng Tang, Shunxing Bao, Richard G. Abramson, Yuankai Huo, Bennett A. Landman

We combine the anatomical prior with corresponding extracted patches to preserve the anatomical locations and boundary information for performing high-resolution segmentation across all organs in a single model.

Organ Segmentation Segmentation

Faster Mean-shift: GPU-accelerated clustering for cosine embedding-based cell segmentation and tracking

1 code implementation28 Jul 2020 Mengyang Zhao, Aadarsh Jha, Quan Liu, Bryan A. Millis, Anita Mahadevan-Jansen, Le Lu, Bennett A. Landman, Matthew J. Tyskac, Yuankai Huo

With both embedding simulation and empirical validation via the four cohorts from the ISBI cell tracking challenge, the proposed Faster Mean-shift algorithm achieved 7-10 times speedup compared to the state-of-the-art embedding based cell instance segmentation and tracking algorithm.

Cell Segmentation Cell Tracking +4

CircleNet: Anchor-free Detection with Circle Representation

1 code implementation3 Jun 2020 Haichun Yang, Ruining Deng, Yuzhe Lu, Zheyu Zhu, Ye Chen, Joseph T. Roland, Le Lu, Bennett A. Landman, Agnes B. Fogo, Yuankai Huo

In this work, we propose CircleNet, a simple anchor-free detection method with circle representation for detection of the ball-shaped glomerulus.

Object object-detection +1

The Value of Nullspace Tuning Using Partial Label Information

no code implementations17 Mar 2020 Colin B. Hansen, Vishwesh Nath, Diego A. Mesa, Yuankai Huo, Bennett A. Landman, Thomas A. Lasko

But in some learning problems, partial label information can be inferred from otherwise unlabeled examples and used to further improve the model.

Deep Learning Estimation of Multi-Tissue Constrained Spherical Deconvolution with Limited Single Shell DW-MRI

no code implementations20 Feb 2020 Vishwesh Nath, Sudhir K. Pathak, Kurt G. Schilling, Walt Schneider, Bennett A. Landman

Herein, we explore the possibility of using deep learning on single shell data (using the b=1000 s/mm2 from the Human Connectome Project (HCP)) to estimate the information content captured by 8th order MT-CSD using the full three shell data (b=1000, 2000, and 3000 s/mm2 from HCP).

Outlier Guided Optimization of Abdominal Segmentation

no code implementations10 Feb 2020 Yuchen Xu, Olivia Tang, Yucheng Tang, Ho Hin Lee, Yunqiang Chen, Dashan Gao, Shizhong Han, Riqiang Gao, Michael R. Savona, Richard G. Abramson, Yuankai Huo, Bennett A. Landman

We built on a pre-trained 3D U-Net model for abdominal multi-organ segmentation and augmented the dataset either with outlier data (e. g., exemplars for which the baseline algorithm failed) or inliers (e. g., exemplars for which the baseline algorithm worked).

Active Learning Computed Tomography (CT) +2

Internal-transfer Weighting of Multi-task Learning for Lung Cancer Detection

1 code implementation16 Dec 2019 Yiyuan Yang, Riqiang Gao, Yucheng Tang, Sanja L. Antic, Steve Deppen, Yuankai Huo, Kim L. Sandler, Pierre P. Massion, Bennett A. Landman

To improve performance on the primary task, we propose an Internal-Transfer Weighting (ITW) strategy to suppress the loss functions on auxiliary tasks for the final stages of training.

Multi-Task Learning

MRI correlates of chronic symptoms in mild traumatic brain injury

no code implementations6 Dec 2019 Cailey I. Kerley, Kurt G. Schilling, Justin Blaber, Beth Miller, Allen Newton, Adam W. Anderson, Bennett A. Landman, Tonia S. Rex

Veterans with mild traumatic brain injury (mTBI) have reported auditory and visual dysfunction that persists beyond the acute incident.

Contrast Phase Classification with a Generative Adversarial Network

no code implementations14 Nov 2019 Yucheng Tang, Ho Hin Lee, Yuchen Xu, Olivia Tang, Yunqiang Chen, Dashan Gao, Shizhong Han, Riqiang Gao, Camilo Bermudez, Michael R. Savona, Richard G. Abramson, Yuankai Huo, Bennett A. Landman

Dynamic contrast enhanced computed tomography (CT) is an imaging technique that provides critical information on the relationship of vascular structure and dynamics in the context of underlying anatomy.

Anatomy Classification +4

Deep Learning Captures More Accurate Diffusion Fiber Orientations Distributions than Constrained Spherical Deconvolution

no code implementations13 Nov 2019 Vishwesh Nath, Kurt G. Schilling, Colin B. Hansen, Prasanna Parvathaneni, Allison E. Hainline, Camilo Bermudez, Andrew J. Plassard, Vaibhav Janve, Yurui Gao, Justin A. Blaber, Iwona Stępniewska, Adam W. Anderson, Bennett A. Landman

Confocal histology provides an opportunity to establish intra-voxel fiber orientation distributions that can be used to quantitatively assess the biological relevance of diffusion weighted MRI models, e. g., constrained spherical deconvolution (CSD).

Extracting 2D weak labels from volume labels using multiple instance learning in CT hemorrhage detection

1 code implementation13 Nov 2019 Samuel W. Remedios, Zihao Wu, Camilo Bermudez, Cailey I. Kerley, Snehashis Roy, Mayur B. Patel, John A. Butman, Bennett A. Landman, Dzung L. Pham

Multiple instance learning (MIL) is a supervised learning methodology that aims to allow models to learn instance class labels from bag class labels, where a bag is defined to contain multiple instances.

Multiple Instance Learning

Semi-Supervised Multi-Organ Segmentation through Quality Assurance Supervision

no code implementations12 Nov 2019 Ho Hin Lee, Yucheng Tang, Olivia Tang, Yuchen Xu, Yunqiang Chen, Dashan Gao, Shizhong Han, Riqiang Gao, Michael R. Savona, Richard G. Abramson, Yuankai Huo, Bennett A. Landman

The contributions of the proposed method are threefold: We show that (1) the QA scores can be used as a loss function to perform semi-supervised learning for unlabeled data, (2) the well trained discriminator is learnt by QA score rather than traditional true/false, and (3) the performance of multi-organ segmentation on unlabeled datasets can be fine-tuned with more robust and higher accuracy than the original baseline method.

Image Segmentation Medical Image Segmentation +3

Fully Automatic Liver Attenuation Estimation Combing CNN Segmentation and Morphological Operations

1 code implementation23 Jun 2019 Yuankai Huo, James G. Terry, Jiachen Wang, Sangeeta Nair, Thomas A. Lasko, Barry I. Freedman, J. Jeffery Carr, Bennett A. Landman

Manually tracing regions of interest (ROIs) within the liver is the de facto standard method for measuring liver attenuation on computed tomography (CT) in diagnosing nonalcoholic fatty liver disease (NAFLD).

Computed Tomography (CT) Liver Segmentation +1

3D Whole Brain Segmentation using Spatially Localized Atlas Network Tiles

2 code implementations28 Mar 2019 Yuankai Huo, Zhoubing Xu, Yunxi Xiong, Katherine Aboud, Prasanna Parvathaneni, Shunxing Bao, Camilo Bermudez, Susan M. Resnick, Laurie E. Cutting, Bennett A. Landman

To address the first challenge, multiple spatially distributed networks were used in the SLANT method, in which each network learned contextual information for a fixed spatial location.

Brain Segmentation Segmentation

Lung Cancer Detection using Co-learning from Chest CT Images and Clinical Demographics

no code implementations21 Feb 2019 Jiachen Wang, Riqiang Gao, Yuankai Huo, Shunxing Bao, Yunxi Xiong, Sanja L. Antic, Travis J. Osterman, Pierre P. Massion, Bennett A. Landman

The results show that the AUC obtained from clinical demographics alone was 0. 635 while the attention network alone reached an accuracy of 0. 687.

Computed Tomography (CT)

Reproducibility Evaluation of SLANT Whole Brain Segmentation Across Clinical Magnetic Resonance Imaging Protocols

no code implementations7 Jan 2019 Yunxi Xiong, Yuankai Huo, Jiachen Wang, L. Taylor Davis, Maureen McHugo, Bennett A. Landman

Recently, we obtained a clinically acquired, multi-sequence MRI brain cohort with 1480 clinically acquired, de-identified brain MRI scans on 395 patients using seven different MRI protocols.

Brain Segmentation Computational Efficiency +1

Montage based 3D Medical Image Retrieval from Traumatic Brain Injury Cohort using Deep Convolutional Neural Network

no code implementations10 Dec 2018 Cailey I. Kerley, Yuankai Huo, Shikha Chaganti, Shunxing Bao, Mayur B. Patel, Bennett A. Landman

For instance, in a typical sample of clinical TBI imaging cohort, only ~15% of CT scans actually contain whole brain CT images suitable for volumetric brain analyses; the remaining are partial brain or non-brain images.

Computed Tomography (CT) Medical Image Retrieval +1

Towards Machine Learning Prediction of Deep Brain Stimulation (DBS) Intra-operative Efficacy Maps

no code implementations26 Nov 2018 Camilo Bermudez, William Rodriguez, Yuankai Huo, Allison E. Hainline, Rui Li, Robert Shults, Pierre D. DHaese, Peter E. Konrad, Benoit M. Dawant, Bennett A. Landman

We show an improvement in the classification of intraoperative stimulation coordinates as a positive response in reduction of symptoms with AUC of 0. 670 compared to a baseline registration-based approach, which achieves an AUC of 0. 627 (p < 0. 01).

Anatomy BIG-bench Machine Learning +1

Splenomegaly Segmentation on Multi-modal MRI using Deep Convolutional Networks

no code implementations9 Nov 2018 Yuankai Huo, Zhoubing Xu, Shunxing Bao, Camilo Bermudez, Hyeonsoo Moon, Prasanna Parvathaneni, Tamara K. Moyo, Michael R. Savona, Albert Assad, Richard G. Abramson, Bennett A. Landman

A clinically acquired cohort containing both T1-weighted (T1w) and T2-weighted (T2w) MRI splenomegaly scans was used to train and evaluate the performance of multi-atlas segmentation (MAS), 2D DCNN networks, and a 3D DCNN network.

Segmentation Splenomegaly Segmentation On Multi-Modal Mri

SynSeg-Net: Synthetic Segmentation Without Target Modality Ground Truth

1 code implementation15 Oct 2018 Yuankai Huo, Zhoubing Xu, Hyeonsoo Moon, Shunxing Bao, Albert Assad, Tamara K. Moyo, Michael R. Savona, Richard G. Abramson, Bennett A. Landman

SynSeg-Net is trained by using (1) unpaired intensity images from source and target modalities, and (2) manual labels only from source modality.

Image Segmentation Segmentation +1

Data-driven Probabilistic Atlases Capture Whole-brain Individual Variation

no code implementations6 Jun 2018 Yuankai Huo, Katherine Swett, Susan M. Resnick, Laurie E. Cutting, Bennett A. Landman

By indexing the dictionary, the whole brain probabilistic atlases adapt to each new subject quickly and can be used as spatial priors for visualization and processing.

Specificity

Adversarial Synthesis Learning Enables Segmentation Without Target Modality Ground Truth

1 code implementation20 Dec 2017 Yuankai Huo, Zhoubing Xu, Shunxing Bao, Albert Assad, Richard G. Abramson, Bennett A. Landman

Herein, we proposed a novel end-to-end synthesis and segmentation network (EssNet) to achieve the unpaired MRI to CT image synthesis and CT splenomegaly segmentation simultaneously without using manual labels on CT.

Image-to-Image Translation Medical Image Segmentation +2

Improved Stability of Whole Brain Surface Parcellation with Multi-Atlas Segmentation

no code implementations2 Dec 2017 Yuankai Huo, Shunxing Bao, Prasanna Parvathaneni, Bennett A. Landman

Herein, the MaCRUISE surface parcellation (MaCRUISEsp) method is proposed to perform the surface parcellation upon the inner, central and outer surfaces that are reconstructed from MaCRUISE.

Brain Segmentation Segmentation +1

4D Multi-atlas Label Fusion using Longitudinal Images

no code implementations29 Aug 2017 Yuankai Huo, Susan M. Resnick, Bennett A. Landman

(2) The proposed algorithm is a longitudinal generalization of a lead-ing joint label fusion method (JLF) that has proven adaptable to a wide variety of applications.

Image Segmentation Medical Image Segmentation +2

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