no code implementations • 27 Mar 2024 • Tian Yu, Yunhe Li, Michael E. Kim, Chenyu Gao, Qi Yang, Leon Y. Cai, Susane M. Resnick, Lori L. Beason-Held, Daniel C. Moyer, Kurt G. Schilling, Bennett A. Landman
Diffusion MRI (dMRI) streamline tractography, the gold standard for in vivo estimation of brain white matter (WM) pathways, has long been considered indicative of macroscopic relationships with WM microstructure.
no code implementations • 8 Feb 2024 • Thomas A. Lasko, John M. Still, Thomas Z. Li, Marco Barbero Mota, William W. Stead, Eric V. Strobl, Bennett A. Landman, Fabien Maldonado
Insufficiently precise diagnosis of clinical disease is likely responsible for many treatment failures, even for common conditions and treatments.
no code implementations • 15 Jan 2024 • Ho Hin Lee, Yu Gu, Theodore Zhao, Yanbo Xu, Jianwei Yang, Naoto Usuyama, Cliff Wong, Mu Wei, Bennett A. Landman, Yuankai Huo, Alberto Santamaria-Pang, Hoifung Poon
This transformative technology, originally developed for general-purpose computer vision, has found rapid application in medical image processing.
no code implementations • 11 Jan 2024 • Lucas W. Remedios, Shunxing Bao, Samuel W. Remedios, Ho Hin Lee, Leon Y. Cai, Thomas Li, Ruining Deng, Can Cui, Jia Li, Qi Liu, Ken S. Lau, Joseph T. Roland, Mary K. Washington, Lori A. Coburn, Keith T. Wilson, Yuankai Huo, Bennett A. Landman
In this paper, we propose to use inter-modality learning to label previously un-labelable cell types on virtual H&E.
no code implementations • 9 Jan 2024 • Hanliang Xu, Nancy R. Newlin, Michael E. Kim, Chenyu Gao, Praitayini Kanakaraj, Aravind R. Krishnan, Lucas W. Remedios, Nazirah Mohd Khairi, Kimberly Pechman, Derek Archer, Timothy J. Hohman, Angela L. Jefferson, The BIOCARD Study Team, Ivana Isgum, Yuankai Huo, Daniel Moyer, Kurt G. Schilling, Bennett A. Landman
First, we plotted the graph measures and used coefficient of variation (CoV) and the Mann-Whitney U test to evaluate different methods' effectiveness in removing site effects on the matrices and the derived graph measures.
no code implementations • 5 Jan 2024 • Ho Hin Lee, Adam M. Saunders, Michael E. Kim, Samuel W. Remedios, Yucheng Tang, Qi Yang, Xin Yu, Shunxing Bao, Chloe Cho, Louise A. Mawn, Tonia S. Rex, Kevin L. Schey, Blake E. Dewey, Jeffrey M. Spraggins, Jerry L. Prince, Yuankai Huo, Bennett A. Landman
These variations limit the feasibility and robustness of generalizing population-wise features of eye organs to an unbiased spatial reference.
no code implementations • 24 Nov 2023 • M. Jorge Cardoso, Julia Moosbauer, Tessa S. Cook, B. Selnur Erdal, Brad Genereaux, Vikash Gupta, Bennett A. Landman, Tiarna Lee, Parashkev Nachev, Elanchezhian Somasundaram, Ronald M. Summers, Khaled Younis, Sebastien Ourselin, Franz MJ Pfister
The integration of AI into radiology introduces opportunities for improved clinical care provision and efficiency but it demands a meticulous approach to mitigate potential risks as with any other new technology.
no code implementations • 6 Nov 2023 • Chenyu Gao, Michael E. Kim, Ho Hin Lee, Qi Yang, Nazirah Mohd Khairi, Praitayini Kanakaraj, Nancy R. Newlin, Derek B. Archer, Angela L. Jefferson, Warren D. Taylor, Brian D. Boyd, Lori L. Beason-Held, Susan M. Resnick, The BIOCARD Study Team, Yuankai Huo, Katherine D. Van Schaik, Kurt G. Schilling, Daniel Moyer, Ivana Išgum, Bennett A. Landman
We find that the ResNet model captures subtler, non-macrostructural features for brain age prediction.
1 code implementation • 30 Sep 2023 • Ho Hin Lee, Quan Liu, Qi Yang, Xin Yu, Shunxing Bao, Yuankai Huo, Bennett A. Landman
We hypothesize that deformable convolution can be an exploratory alternative to combine all advantages from the previous operators, providing long-range dependency, adaptive spatial aggregation and computational efficiency as a foundation backbone.
no code implementations • 22 Sep 2023 • Aravind R. Krishnan, Kaiwen Xu, Thomas Li, Chenyu Gao, Lucas W. Remedios, Praitayini Kanakaraj, Ho Hin Lee, Shunxing Bao, Kim L. Sandler, Fabien Maldonado, Ivana Isgum, Bennett A. Landman
In this study, we adopt an unpaired image translation approach to investigate harmonization between and across reconstruction kernels from different manufacturers by constructing a multipath cycle generative adversarial network (GAN).
1 code implementation • 17 Sep 2023 • Xin Yu, Qi Yang, Yucheng Tang, Riqiang Gao, Shunxing Bao, Leon Y. Cai, Ho Hin Lee, Yuankai Huo, Ann Zenobia Moore, Luigi Ferrucci, Bennett A. Landman
We further evaluate our method's capability to harmonize longitudinal positional variation on 1033 subjects from the Baltimore Longitudinal Study of Aging (BLSA) dataset, which contains longitudinal single abdominal slices, and confirmed that our method can harmonize the slice positional variance in terms of visceral fat area.
1 code implementation • 8 Sep 2023 • Xin Yu, Yucheng Tang, Qi Yang, Ho Hin Lee, Shunxing Bao, Yuankai Huo, Bennett A. Landman
Subsequently, the model is finetuned with 45 T1w 3D volumes from Open Access Series Imaging Studies (OASIS) where both 133 whole brain classes and TICV/PFV labels are available.
no code implementations • 20 Aug 2023 • Shunxing Bao, Sichen Zhu, Vasantha L Kolachala, Lucas W. Remedios, Yeonjoo Hwang, Yutong Sun, Ruining Deng, Can Cui, Yike Li, Jia Li, Joseph T. Roland, Qi Liu, Ken S. Lau, Subra Kugathasan, Peng Qiu, Keith T. Wilson, Lori A. Coburn, Bennett A. Landman, Yuankai Huo
This analysis is based on data collected at the two research institutes.
no code implementations • 3 Jul 2023 • Can Cui, Yaohong Wang, Shunxing Bao, Yucheng Tang, Ruining Deng, Lucas W. Remedios, Zuhayr Asad, Joseph T. Roland, Ken S. Lau, Qi Liu, Lori A. Coburn, Keith T. Wilson, Bennett A. Landman, Yuankai Huo
Many anomaly detection approaches, especially deep learning methods, have been recently developed to identify abnormal image morphology by only employing normal images during training.
no code implementations • 5 Jun 2023 • Tianyuan Yao, Francois Rheault, Leon Y Cai, Vishwesh Nath, Zuhayr Asad, Nancy Newlin, Can Cui, Ruining Deng, Karthik Ramadass, Andrea Shafer, Susan Resnick, Kurt Schilling, Bennett A. Landman, Yuankai Huo
From the experimental results, the proposed data-driven framework outperforms the existing benchmarks in repeated fODF estimation.
no code implementations • 2 Jun 2023 • Yinchi Zhou, Ho Hin Lee, Yucheng Tang, Xin Yu, Qi Yang, Shunxing Bao, Jeffrey M. Spraggins, Yuankai Huo, Bennett A. Landman
Briefly, DEEDs affine and non-rigid registration are performed to transfer patient abdominal volumes to a fixed high-resolution atlas template.
no code implementations • 24 Apr 2023 • Lucas W. Remedios, Leon Y. Cai, Samuel W. Remedios, Karthik Ramadass, Aravind Krishnan, Ruining Deng, Can Cui, Shunxing Bao, Lori A. Coburn, Yuankai Huo, Bennett A. Landman
The M1 Ultra SoC was able to train the model directly on gigapixel images (16000$\times$64000 pixels, 1. 024 billion pixels) with a batch size of 1 using over 100 GB of unified memory for the process at an average speed of 1 minute and 21 seconds per batch with Tensorflow 2/Keras.
no code implementations • 9 Apr 2023 • Ruining Deng, Can Cui, Quan Liu, Tianyuan Yao, Lucas W. Remedios, Shunxing Bao, Bennett A. Landman, Lee E. Wheless, Lori A. Coburn, Keith T. Wilson, Yaohong Wang, Shilin Zhao, Agnes B. Fogo, Haichun Yang, Yucheng Tang, Yuankai Huo
However, it does not consistently achieve satisfying performance for dense instance object segmentation, even with 20 prompts (clicks/boxes) on each image.
no code implementations • 7 Apr 2023 • Kaiwen Xu, Aravind R. Krishnan, Thomas Z. Li, Yuankai Huo, Kim L. Sandler, Fabien Maldonado, Bennett A. Landman
Anatomically consistent field-of-view (FOV) completion to recover truncated body sections has important applications in quantitative analyses of computed tomography (CT) with limited FOV.
1 code implementation • 6 Apr 2023 • Thomas Z. Li, John M. Still, Kaiwen Xu, Ho Hin Lee, Leon Y. Cai, Aravind R. Krishnan, Riqiang Gao, Mirza S. Khan, Sanja Antic, Michael Kammer, Kim L. Sandler, Fabien Maldonado, Bennett A. Landman, Thomas A. Lasko
In this work, we propose a transformer-based multimodal strategy to integrate repeat imaging with longitudinal clinical signatures from routinely collected EHRs for SPN classification.
1 code implementation • 1 Apr 2023 • Ruining Deng, Can Cui, Lucas W. Remedios, Shunxing Bao, R. Michael Womick, Sophie Chiron, Jia Li, Joseph T. Roland, Ken S. Lau, Qi Liu, Keith T. Wilson, Yaohong Wang, Lori A. Coburn, Bennett A. Landman, Yuankai Huo
Analyzing high resolution whole slide images (WSIs) with regard to information across multiple scales poses a significant challenge in digital pathology.
no code implementations • 29 Mar 2023 • Tianyuan Yao, Nancy Newlin, Praitayini Kanakaraj, Vishwesh Nath, Leon Y Cai, Karthik Ramadass, Kurt Schilling, Bennett A. Landman, Yuankai Huo
Diffusion-weighted (DW) MRI measures the direction and scale of the local diffusion process in every voxel through its spectrum in q-space, typically acquired in one or more shells.
2 code implementations • 10 Mar 2023 • Ho Hin Lee, Quan Liu, Shunxing Bao, Qi Yang, Xin Yu, Leon Y. Cai, Thomas Li, Yuankai Huo, Xenofon Koutsoukos, Bennett A. Landman
We hypothesize that convolution with LK sizes is limited to maintain an optimal convergence for locality learning.
no code implementations • 3 Feb 2023 • Annika Reinke, Minu D. Tizabi, Michael Baumgartner, Matthias Eisenmann, Doreen Heckmann-Nötzel, A. Emre Kavur, Tim Rädsch, Carole H. Sudre, Laura Acion, Michela Antonelli, Tal Arbel, Spyridon Bakas, Arriel Benis, Matthew Blaschko, Florian Buettner, M. Jorge Cardoso, Veronika Cheplygina, Jianxu Chen, Evangelia Christodoulou, Beth A. Cimini, Gary S. Collins, Keyvan Farahani, Luciana Ferrer, Adrian Galdran, Bram van Ginneken, Ben Glocker, Patrick Godau, Robert Haase, Daniel A. Hashimoto, Michael M. Hoffman, Merel Huisman, Fabian Isensee, Pierre Jannin, Charles E. Kahn, Dagmar Kainmueller, Bernhard Kainz, Alexandros Karargyris, Alan Karthikesalingam, Hannes Kenngott, Jens Kleesiek, Florian Kofler, Thijs Kooi, Annette Kopp-Schneider, Michal Kozubek, Anna Kreshuk, Tahsin Kurc, Bennett A. Landman, Geert Litjens, Amin Madani, Klaus Maier-Hein, Anne L. Martel, Peter Mattson, Erik Meijering, Bjoern Menze, Karel G. M. Moons, Henning Müller, Brennan Nichyporuk, Felix Nickel, Jens Petersen, Susanne M. Rafelski, Nasir Rajpoot, Mauricio Reyes, Michael A. Riegler, Nicola Rieke, Julio Saez-Rodriguez, Clara I. Sánchez, Shravya Shetty, Maarten van Smeden, Ronald M. Summers, Abdel A. Taha, Aleksei Tiulpin, Sotirios A. Tsaftaris, Ben van Calster, Gaël Varoquaux, Manuel Wiesenfarth, Ziv R. Yaniv, Paul F. Jäger, Lena Maier-Hein
Validation metrics are key for the reliable tracking of scientific progress and for bridging the current chasm between artificial intelligence (AI) research and its translation into practice.
2 code implementations • ICCV 2023 • Jie Liu, Yixiao Zhang, Jie-Neng Chen, Junfei Xiao, Yongyi Lu, Bennett A. Landman, Yixuan Yuan, Alan Yuille, Yucheng Tang, Zongwei Zhou
The proposed model is developed from an assembly of 14 datasets, using a total of 3, 410 CT scans for training and then evaluated on 6, 162 external CT scans from 3 additional datasets.
Ranked #1 on Organ Segmentation on BTCV
1 code implementation • 30 Nov 2022 • Qi Yang, Xin Yu, Ho Hin Lee, Leon Y. Cai, Kaiwen Xu, Shunxing Bao, Yuankai Huo, Ann Zenobia Moore, Sokratis Makrogiannis, Luigi Ferrucci, Bennett A. Landman
The proposed pipeline is effective and robust in extracting muscle groups on 2D single slice CT thigh images. The container is available for public use at https://github. com/MASILab/DA_CT_muscle_seg
1 code implementation • 16 Oct 2022 • Ho Hin Lee, Yucheng Tang, Han Liu, Yubo Fan, Leon Y. Cai, Qi Yang, Xin Yu, Shunxing Bao, Yuankai Huo, Bennett A. Landman
We evaluate our proposed approach on multi-organ segmentation with both non-contrast CT (NCCT) datasets and the MICCAI 2015 BTCV Challenge contrast-enhance CT (CECT) datasets.
2 code implementations • 29 Sep 2022 • Ho Hin Lee, Shunxing Bao, Yuankai Huo, Bennett A. Landman
Hierarchical transformers (e. g., Swin Transformers) reintroduced several ConvNet priors and further enhanced the practical viability of adapting volumetric segmentation in 3D medical datasets.
no code implementations • 28 Sep 2022 • Xin Yu, Yucheng Tang, Qi Yang, Ho Hin Lee, Riqiang Gao, Shunxing Bao, Ann Zenobia Moore, Luigi Ferrucci, Bennett A. Landman
Metabolic health is increasingly implicated as a risk factor across conditions from cardiology to neurology, and efficiency assessment of body composition is critical to quantitatively characterizing these relationships.
1 code implementation • 28 Sep 2022 • Xin Yu, Qi Yang, Yucheng Tang, Riqiang Gao, Shunxing Bao, LeonY. Cai, Ho Hin Lee, Yuankai Huo, Ann Zenobia Moore, Luigi Ferrucci, Bennett A. Landman
External experiments on 20 subjects from the Baltimore Longitudinal Study of Aging (BLSA) dataset that contains longitudinal single abdominal slices validate that our method can harmonize the slice positional variance in terms of muscle and visceral fat area.
1 code implementation • 28 Sep 2022 • Xin Yu, Qi Yang, Yinchi Zhou, Leon Y. Cai, Riqiang Gao, Ho Hin Lee, Thomas Li, Shunxing Bao, Zhoubing Xu, Thomas A. Lasko, Richard G. Abramson, Zizhao Zhang, Yuankai Huo, Bennett A. Landman, Yucheng Tang
Transformer-based models, capable of learning better global dependencies, have recently demonstrated exceptional representation learning capabilities in computer vision and medical image analysis.
1 code implementation • 4 Sep 2022 • Thomas Z. Li, Kaiwen Xu, Riqiang Gao, Yucheng Tang, Thomas A. Lasko, Fabien Maldonado, Kim Sandler, Bennett A. Landman
In cross-validation on screening chest CTs from the NLST, our methods (0. 785 and 0. 786 AUC respectively) significantly outperform a cross-sectional approach (0. 734 AUC) and match the discriminative performance of the leading longitudinal medical imaging algorithm (0. 779 AUC) on benign versus malignant classification.
1 code implementation • 30 Aug 2022 • Tianyuan Yao, Chang Qu, Jun Long, Quan Liu, Ruining Deng, Yuanhan Tian, Jiachen Xu, Aadarsh Jha, Zuhayr Asad, Shunxing Bao, Mengyang Zhao, Agnes B. Fogo, Bennett A. Landman, Haichun Yang, Catie Chang, Yuankai Huo
In order to extract and separate compound figures into usable individual images for downstream learning, we propose a simple compound figure separation (SimCFS) framework without using the traditionally required detection bounding box annotations, with a new loss function and a hard case simulation.
1 code implementation • 15 Aug 2022 • Ruining Deng, Can Cui, Lucas W. Remedios, Shunxing Bao, R. Michael Womick, Sophie Chiron, Jia Li, Joseph T. Roland, Ken S. Lau, Qi Liu, Keith T. Wilson, Yaohong Wang, Lori A. Coburn, Bennett A. Landman, Yuankai Huo
Multi-instance learning (MIL) is widely used in the computer-aided interpretation of pathological Whole Slide Images (WSIs) to solve the lack of pixel-wise or patch-wise annotations.
1 code implementation • 13 Jul 2022 • Kaiwen Xu, Thomas Li, Mirza S. Khan, Riqiang Gao, Sanja L. Antic, Yuankai Huo, Kim L. Sandler, Fabien Maldonado, Bennett A. Landman
We evaluate the validity of the proposed method in automatic BC assessment using lung screening CT with limited FOV.
1 code implementation • 3 Jun 2022 • Lena Maier-Hein, Annika Reinke, Patrick Godau, Minu D. Tizabi, Florian Buettner, Evangelia Christodoulou, Ben Glocker, Fabian Isensee, Jens Kleesiek, Michal Kozubek, Mauricio Reyes, Michael A. Riegler, Manuel Wiesenfarth, A. Emre Kavur, Carole H. Sudre, Michael Baumgartner, Matthias Eisenmann, Doreen Heckmann-Nötzel, Tim Rädsch, Laura Acion, Michela Antonelli, Tal Arbel, Spyridon Bakas, Arriel Benis, Matthew Blaschko, M. Jorge Cardoso, Veronika Cheplygina, Beth A. Cimini, Gary S. Collins, Keyvan Farahani, Luciana Ferrer, Adrian Galdran, Bram van Ginneken, Robert Haase, Daniel A. Hashimoto, Michael M. Hoffman, Merel Huisman, Pierre Jannin, Charles E. Kahn, Dagmar Kainmueller, Bernhard Kainz, Alexandros Karargyris, Alan Karthikesalingam, Hannes Kenngott, Florian Kofler, Annette Kopp-Schneider, Anna Kreshuk, Tahsin Kurc, Bennett A. Landman, Geert Litjens, Amin Madani, Klaus Maier-Hein, Anne L. Martel, Peter Mattson, Erik Meijering, Bjoern Menze, Karel G. M. Moons, Henning Müller, Brennan Nichyporuk, Felix Nickel, Jens Petersen, Nasir Rajpoot, Nicola Rieke, Julio Saez-Rodriguez, Clara I. Sánchez, Shravya Shetty, Maarten van Smeden, Ronald M. Summers, Abdel A. Taha, Aleksei Tiulpin, Sotirios A. Tsaftaris, Ben van Calster, Gaël Varoquaux, Paul F. Jäger
The framework was developed in a multi-stage Delphi process and is based on the novel concept of a problem fingerprint - a structured representation of the given problem that captures all aspects that are relevant for metric selection, from the domain interest to the properties of the target structure(s), data set and algorithm output.
no code implementations • 2 Jun 2022 • Jun Li, Junyu Chen, Yucheng Tang, Ce Wang, Bennett A. Landman, S. Kevin Zhou
Transformer, the latest technological advance of deep learning, has gained prevalence in natural language processing or computer vision.
no code implementations • 12 May 2022 • Ho Hin Lee, Yucheng Tang, Riqiang Gao, Qi Yang, Xin Yu, Shunxing Bao, James G. Terry, J. Jeffrey Carr, Yuankai Huo, Bennett A. Landman
In this paper, we propose a novel unsupervised approach that leverages pairwise contrast-enhanced CT (CECT) context to compute non-contrast segmentation without ground-truth label.
no code implementations • 25 Mar 2022 • Can Cui, Haichun Yang, Yaohong Wang, Shilin Zhao, Zuhayr Asad, Lori A. Coburn, Keith T. Wilson, Bennett A. Landman, Yuankai Huo
The rapid development of diagnostic technologies in healthcare is leading to higher requirements for physicians to handle and integrate the heterogeneous, yet complementary data that are produced during routine practice.
no code implementations • 8 Mar 2022 • Can Cui, Han Liu, Quan Liu, Ruining Deng, Zuhayr Asad, Yaohong WangShilin Zhao, Haichun Yang, Bennett A. Landman, Yuankai Huo
Thus, there are still open questions on how to effectively predict brain cancer survival from the incomplete radiological, pathological, genomic, and demographic data (e. g., one or more modalities might not be collected for a patient).
no code implementations • 4 Mar 2022 • Xin Yu, Yucheng Tang, Yinchi Zhou, Riqiang Gao, Qi Yang, Ho Hin Lee, Thomas Li, Shunxing Bao, Yuankai Huo, Zhoubing Xu, Thomas A. Lasko, Richard G. Abramson, Bennett A. Landman
Efficiently quantifying renal structures can provide distinct spatial context and facilitate biomarker discovery for kidney morphology.
1 code implementation • 22 Oct 2021 • Ethan H. Nguyen, Haichun Yang, Ruining Deng, Yuzhe Lu, Zheyu Zhu, Joseph T. Roland, Le Lu, Bennett A. Landman, Agnes B. Fogo, Yuankai Huo
Compared with the conventional bounding box representation, the proposed bounding circle representation innovates in three-fold: (1) it is optimized for ball-shaped biomedical objects; (2) The circle representation reduced the degree of freedom compared with box representation; (3) It is naturally more rotation invariant.
Ranked #1 on Medical Object Detection on MoNuSeg 2018
no code implementations • 29 Sep 2021 • Riqiang Gao, Zhoubing Xu, Guillaume Chabin, Awais Mansoor, Florin-Cristian Ghesu, Bogdan Georgescu, Bennett A. Landman, Sasa Grbic
A Bad-GAN generates pseudo anomalies at the low-density area of inlier distribution, and thus the inlier/outlier distinction can be approximated.
no code implementations • MICCAI Workshop COMPAY 2021 • Shunxing Bao, Yucheng Tang, Ho Hin Lee, Riqiang Gao, Sophie Chiron, Ilwoo Lyu, Lori A. Coburn, Keith T. Wilson, Joseph T. Roland, Bennett A. Landman, Yuankai Huo
Our contribution is three-fold: (1) a single deep network framework is proposed to tackle missing stain in MxIF; (2) the proposed 'N-to-N' strategy reduces theoretical four years of computational time to 20 hours when covering all possible missing stains scenarios, with up to five missing stains (e. g., '(N-1)-to-1', '(N-2)-to-2'); and (3) this work is the first comprehensive experimental study of investigating cross-stain synthesis in MxIF.
1 code implementation • 27 Jul 2021 • Riqiang Gao, Mirza S. Khan, Yucheng Tang, Kaiwen Xu, Steve Deppen, Yuankai Huo, Kim L. Sandler, Pierre P. Massion, Bennett A. Landman
Image Quality Assessment (IQA) is important for scientific inquiry, especially in medical imaging and machine learning.
no code implementations • 25 Jul 2021 • Riqiang Gao, Yucheng Tang, Kaiwen Xu, Ho Hin Lee, Steve Deppen, Kim Sandler, Pierre Massion, Thomas A. Lasko, Yuankai Huo, Bennett A. Landman
To our knowledge, it is the first generative adversarial model that addresses multi-modal missing imputation by modeling the joint distribution of image and non-image data.
1 code implementation • 19 Jul 2021 • Tianyuan Yao, Chang Qu, Quan Liu, Ruining Deng, Yuanhan Tian, Jiachen Xu, Aadarsh Jha, Shunxing Bao, Mengyang Zhao, Agnes B. Fogo, Bennett A. Landman, Catie Chang, Haichun Yang, Yuankai Huo
Our technical contribution is three-fold: (1) we introduce a new side loss that is designed for compound figure separation; (2) we introduce an intra-class image augmentation method to simulate hard cases; (3) the proposed framework enables an efficient deployment to new classes of images, without requiring resource extensive bounding box annotations.
1 code implementation • 10 Jun 2021 • Michela Antonelli, Annika Reinke, Spyridon Bakas, Keyvan Farahani, AnnetteKopp-Schneider, Bennett A. Landman, Geert Litjens, Bjoern Menze, Olaf Ronneberger, Ronald M. Summers, Bram van Ginneken, Michel Bilello, Patrick Bilic, Patrick F. Christ, Richard K. G. Do, Marc J. Gollub, Stephan H. Heckers, William R. Jarnagin, Maureen K. McHugo, Sandy Napel, Jennifer S. Goli Pernicka, Kawal Rhode, Catalina Tobon-Gomez, Eugene Vorontsov, Henkjan Huisman, James A. Meakin, Sebastien Ourselin, Manuel Wiesenfarth, Pablo Arbelaez, Byeonguk Bae, Sihong Chen, Laura Daza, Jianjiang Feng, Baochun He, Fabian Isensee, Yuanfeng Ji, Fucang Jia, Namkug Kim, Ildoo Kim, Dorit Merhof, Akshay Pai, Beomhee Park, Mathias Perslev, Ramin Rezaiifar, Oliver Rippel, Ignacio Sarasua, Wei Shen, Jaemin Son, Christian Wachinger, Liansheng Wang, Yan Wang, Yingda Xia, Daguang Xu, Zhanwei Xu, Yefeng Zheng, Amber L. Simpson, Lena Maier-Hein, M. Jorge Cardoso
Segmentation is so far the most widely investigated medical image processing task, but the various segmentation challenges have typically been organized in isolation, such that algorithm development was driven by the need to tackle a single specific clinical problem.
no code implementations • 3 Jun 2021 • Ho Hin Lee, Yucheng Tang, Qi Yang, Xin Yu, Shunxing Bao, Leon Y. Cai, Lucas W. Remedios, Bennett A. Landman, Yuankai Huo
Medical image segmentation, or computing voxelwise semantic masks, is a fundamental yet challenging task to compute a voxel-level semantic mask.
1 code implementation • 12 Apr 2021 • Annika Reinke, Minu D. Tizabi, Carole H. Sudre, Matthias Eisenmann, Tim Rädsch, Michael Baumgartner, Laura Acion, Michela Antonelli, Tal Arbel, Spyridon Bakas, Peter Bankhead, Arriel Benis, Matthew Blaschko, Florian Buettner, M. Jorge Cardoso, Jianxu Chen, Veronika Cheplygina, Evangelia Christodoulou, Beth Cimini, Gary S. Collins, Sandy Engelhardt, Keyvan Farahani, Luciana Ferrer, Adrian Galdran, Bram van Ginneken, Ben Glocker, Patrick Godau, Robert Haase, Fred Hamprecht, Daniel A. Hashimoto, Doreen Heckmann-Nötzel, Peter Hirsch, Michael M. Hoffman, Merel Huisman, Fabian Isensee, Pierre Jannin, Charles E. Kahn, Dagmar Kainmueller, Bernhard Kainz, Alexandros Karargyris, Alan Karthikesalingam, A. Emre Kavur, Hannes Kenngott, Jens Kleesiek, Andreas Kleppe, Sven Kohler, Florian Kofler, Annette Kopp-Schneider, Thijs Kooi, Michal Kozubek, Anna Kreshuk, Tahsin Kurc, Bennett A. Landman, Geert Litjens, Amin Madani, Klaus Maier-Hein, Anne L. Martel, Peter Mattson, Erik Meijering, Bjoern Menze, David Moher, Karel G. M. Moons, Henning Müller, Brennan Nichyporuk, Felix Nickel, M. Alican Noyan, Jens Petersen, Gorkem Polat, Susanne M. Rafelski, Nasir Rajpoot, Mauricio Reyes, Nicola Rieke, Michael Riegler, Hassan Rivaz, Julio Saez-Rodriguez, Clara I. Sánchez, Julien Schroeter, Anindo Saha, M. Alper Selver, Lalith Sharan, Shravya Shetty, Maarten van Smeden, Bram Stieltjes, Ronald M. Summers, Abdel A. Taha, Aleksei Tiulpin, Sotirios A. Tsaftaris, Ben van Calster, Gaël Varoquaux, Manuel Wiesenfarth, Ziv R. Yaniv, Paul Jäger, Lena Maier-Hein
While the importance of automatic image analysis is continuously increasing, recent meta-research revealed major flaws with respect to algorithm validation.
no code implementations • 7 Jan 2021 • Vishwesh Nath, Dong Yang, Bennett A. Landman, Daguang Xu, Holger R. Roth
The primary advantage being that active learning frameworks select data points that can accelerate the learning process of a model and can reduce the amount of data needed to achieve full accuracy as compared to a model trained on a randomly acquired data set.
1 code implementation • 23 Dec 2020 • Ho Hin Lee, Yucheng Tang, Shunxing Bao, Richard G. Abramson, Yuankai Huo, Bennett A. Landman
We combine the anatomical prior with corresponding extracted patches to preserve the anatomical locations and boundary information for performing high-resolution segmentation across all organs in a single model.
no code implementations • 23 Dec 2020 • Ho Hin Lee, Yucheng Tang, Kaiwen Xu, Shunxing Bao, Agnes B. Fogo, Raymond Harris, Mark P. de Caestecker, Mattias Heinrich, Jeffrey M. Spraggins, Yuankai Huo, Bennett A. Landman
However, there is no abdominal and retroperitoneal organs atlas framework for multi-contrast CT.
no code implementations • 5 Dec 2020 • Kaiwen Xu, Riqiang Gao, Mirza S. Khan, Shunxing Bao, Yucheng Tang, Steve A. Deppen, Yuankai Huo, Kim L. Sandler, Pierre P. Massion, Mattias P. Heinrich, Bennett A. Landman
For the entire study cohort, the optimized pipeline achieves a registration success rate of 91. 7%.
no code implementations • 18 Nov 2020 • Cailey I. Kerley, Leon Y. Cai, Chang Yu, Logan M. Crawford, Jason M. Elenberger, Eden S. Singh, Kurt G. Schilling, Katherine S. Aboud, Bennett A. Landman, Tonia S. Rex
We then applied independent component analysis (ICA) both to each PCA space individually and together in a joint ICA approach.
no code implementations • 19 Oct 2020 • Riqiang Gao, Yucheng Tang, Kaiwen Xu, Michael N. Kammer, Sanja L. Antic, Steve Deppen, Kim L. Sandler, Pierre P. Massion, Yuankai Huo, Bennett A. Landman
The network can be trained end-to-end with both medical image features and CDEs/biomarkers, or make a prediction with single modality.
1 code implementation • 28 Jul 2020 • Mengyang Zhao, Aadarsh Jha, Quan Liu, Bryan A. Millis, Anita Mahadevan-Jansen, Le Lu, Bennett A. Landman, Matthew J. Tyskac, Yuankai Huo
With both embedding simulation and empirical validation via the four cohorts from the ISBI cell tracking challenge, the proposed Faster Mean-shift algorithm achieved 7-10 times speedup compared to the state-of-the-art embedding based cell instance segmentation and tracking algorithm.
no code implementations • 28 Jun 2020 • Yuankai Huo, Jinzheng Cai, Chi-Tung Cheng, Ashwin Raju, Ke Yan, Bennett A. Landman, Jing Xiao, Le Lu, Chien-Hung Liao, Adam P. Harrison
To this end, we propose a fully-automated and multi-stage liver tumor characterization framework designed for dynamic contrast computed tomography (CT).
1 code implementation • 3 Jun 2020 • Haichun Yang, Ruining Deng, Yuzhe Lu, Zheyu Zhu, Ye Chen, Joseph T. Roland, Le Lu, Bennett A. Landman, Agnes B. Fogo, Yuankai Huo
In this work, we propose CircleNet, a simple anchor-free detection method with circle representation for detection of the ball-shaped glomerulus.
no code implementations • 17 Mar 2020 • Colin B. Hansen, Vishwesh Nath, Diego A. Mesa, Yuankai Huo, Bennett A. Landman, Thomas A. Lasko
But in some learning problems, partial label information can be inferred from otherwise unlabeled examples and used to further improve the model.
no code implementations • 20 Feb 2020 • Vishwesh Nath, Sudhir K. Pathak, Kurt G. Schilling, Walt Schneider, Bennett A. Landman
Herein, we explore the possibility of using deep learning on single shell data (using the b=1000 s/mm2 from the Human Connectome Project (HCP)) to estimate the information content captured by 8th order MT-CSD using the full three shell data (b=1000, 2000, and 3000 s/mm2 from HCP).
no code implementations • 10 Feb 2020 • Yuchen Xu, Olivia Tang, Yucheng Tang, Ho Hin Lee, Yunqiang Chen, Dashan Gao, Shizhong Han, Riqiang Gao, Michael R. Savona, Richard G. Abramson, Yuankai Huo, Bennett A. Landman
A 2015 MICCAI challenge spurred substantial innovation in multi-organ abdominal CT segmentation with both traditional and deep learning methods.
no code implementations • 10 Feb 2020 • Yuchen Xu, Olivia Tang, Yucheng Tang, Ho Hin Lee, Yunqiang Chen, Dashan Gao, Shizhong Han, Riqiang Gao, Michael R. Savona, Richard G. Abramson, Yuankai Huo, Bennett A. Landman
We built on a pre-trained 3D U-Net model for abdominal multi-organ segmentation and augmented the dataset either with outlier data (e. g., exemplars for which the baseline algorithm failed) or inliers (e. g., exemplars for which the baseline algorithm worked).
1 code implementation • 16 Dec 2019 • Yiyuan Yang, Riqiang Gao, Yucheng Tang, Sanja L. Antic, Steve Deppen, Yuankai Huo, Kim L. Sandler, Pierre P. Massion, Bennett A. Landman
To improve performance on the primary task, we propose an Internal-Transfer Weighting (ITW) strategy to suppress the loss functions on auxiliary tasks for the final stages of training.
no code implementations • 6 Dec 2019 • Cailey I. Kerley, Kurt G. Schilling, Justin Blaber, Beth Miller, Allen Newton, Adam W. Anderson, Bennett A. Landman, Tonia S. Rex
Veterans with mild traumatic brain injury (mTBI) have reported auditory and visual dysfunction that persists beyond the acute incident.
no code implementations • 1 Dec 2019 • Yuankai Huo, Yucheng Tang, Yunqiang Chen, Dashan Gao, Shizhong Han, Shunxing Bao, Smita De, James G. Terry, Jeffrey J. Carr, Richard G. Abramson, Bennett A. Landman
We evaluate the effectiveness of both with and without using soft tissue window normalization on multisite CT cohorts.
no code implementations • 14 Nov 2019 • Yucheng Tang, Ho Hin Lee, Yuchen Xu, Olivia Tang, Yunqiang Chen, Dashan Gao, Shizhong Han, Riqiang Gao, Camilo Bermudez, Michael R. Savona, Richard G. Abramson, Yuankai Huo, Bennett A. Landman
Dynamic contrast enhanced computed tomography (CT) is an imaging technique that provides critical information on the relationship of vascular structure and dynamics in the context of underlying anatomy.
no code implementations • 13 Nov 2019 • Vishwesh Nath, Kurt G. Schilling, Colin B. Hansen, Prasanna Parvathaneni, Allison E. Hainline, Camilo Bermudez, Andrew J. Plassard, Vaibhav Janve, Yurui Gao, Justin A. Blaber, Iwona Stępniewska, Adam W. Anderson, Bennett A. Landman
Confocal histology provides an opportunity to establish intra-voxel fiber orientation distributions that can be used to quantitatively assess the biological relevance of diffusion weighted MRI models, e. g., constrained spherical deconvolution (CSD).
1 code implementation • 13 Nov 2019 • Samuel W. Remedios, Zihao Wu, Camilo Bermudez, Cailey I. Kerley, Snehashis Roy, Mayur B. Patel, John A. Butman, Bennett A. Landman, Dzung L. Pham
Multiple instance learning (MIL) is a supervised learning methodology that aims to allow models to learn instance class labels from bag class labels, where a bag is defined to contain multiple instances.
no code implementations • 12 Nov 2019 • Riqiang Gao, Lingfeng li, Yucheng Tang, Sanja L. Antic, Alexis B. Paulson, Yuankai Huo, Kim L. Sandler, Pierre P. Massion, Bennett A. Landman
Annual low dose computed tomography (CT) lung screening is currently advised for individuals at high risk of lung cancer (e. g., heavy smokers between 55 and 80 years old).
no code implementations • 12 Nov 2019 • Ho Hin Lee, Yucheng Tang, Olivia Tang, Yuchen Xu, Yunqiang Chen, Dashan Gao, Shizhong Han, Riqiang Gao, Michael R. Savona, Richard G. Abramson, Yuankai Huo, Bennett A. Landman
The contributions of the proposed method are threefold: We show that (1) the QA scores can be used as a loss function to perform semi-supervised learning for unlabeled data, (2) the well trained discriminator is learnt by QA score rather than traditional true/false, and (3) the performance of multi-organ segmentation on unlabeled datasets can be fine-tuned with more robust and higher accuracy than the original baseline method.
no code implementations • 11 Oct 2019 • Manuel Wiesenfarth, Annika Reinke, Bennett A. Landman, Manuel Jorge Cardoso, Lena Maier-Hein, Annette Kopp-Schneider
Biomedical challenges have become the de facto standard for benchmarking biomedical image analysis algorithms.
no code implementations • 11 Sep 2019 • Riqiang Gao, Yuankai Huo, Shunxing Bao, Yucheng Tang, Sanja L. Antic, Emily S. Epstein, Aneri B. Balar, Steve Deppen, Alexis B. Paulson, Kim L. Sandler, Pierre P. Massion, Bennett A. Landman
To model both regular and irregular longitudinal samples, we generalize the LSTM model with the Distanced LSTM (DLSTM) for temporally varied acquisitions.
no code implementations • 13 Aug 2019 • Camilo Bermudez, Justin Blaber, Samuel W. Remedios, Jess E. Reynolds, Catherine Lebel, Maureen McHugo, Stephan Heckers, Yuankai Huo, Bennett A. Landman
Generalizability is an important problem in deep neural networks, especially in the context of the variability of data acquisition in clinical magnetic resonance imaging (MRI).
no code implementations • 15 Jul 2019 • Vishwesh Nath, Ilwoo Lyu, Kurt G. Schilling, Prasanna Parvathaneni, Colin B. Hansen, Yucheng Tang, Yuankai Huo, Vaibhav A. Janve, Yurui Gao, Iwona Stepniewska, Adam W. Anderson, Bennett A. Landman
In the in-vivo human data, Deep SHORE was more consistent across scanners with 0. 63 relative to other multi-shell methods 0. 39, 0. 52 and 0. 57 in terms of ACC.
1 code implementation • 23 Jun 2019 • Yuankai Huo, James G. Terry, Jiachen Wang, Sangeeta Nair, Thomas A. Lasko, Barry I. Freedman, J. Jeffery Carr, Bennett A. Landman
Manually tracing regions of interest (ROIs) within the liver is the de facto standard method for measuring liver attenuation on computed tomography (CT) in diagnosing nonalcoholic fatty liver disease (NAFLD).
2 code implementations • 28 Mar 2019 • Yuankai Huo, Zhoubing Xu, Yunxi Xiong, Katherine Aboud, Prasanna Parvathaneni, Shunxing Bao, Camilo Bermudez, Susan M. Resnick, Laurie E. Cutting, Bennett A. Landman
To address the first challenge, multiple spatially distributed networks were used in the SLANT method, in which each network learned contextual information for a fixed spatial location.
no code implementations • 11 Mar 2019 • Samuel Remedios, Snehashis Roy, Justin Blaber, Camilo Bermudez, Vishwesh Nath, Mayur B. Patel, John A. Butman, Bennett A. Landman, Dzung L. Pham
Machine learning models are becoming commonplace in the domain of medical imaging, and with these methods comes an ever-increasing need for more data.
11 code implementations • 25 Feb 2019 • Amber L. Simpson, Michela Antonelli, Spyridon Bakas, Michel Bilello, Keyvan Farahani, Bram van Ginneken, Annette Kopp-Schneider, Bennett A. Landman, Geert Litjens, Bjoern Menze, Olaf Ronneberger, Ronald M. Summers, Patrick Bilic, Patrick F. Christ, Richard K. G. Do, Marc Gollub, Jennifer Golia-Pernicka, Stephan H. Heckers, William R. Jarnagin, Maureen K. McHugo, Sandy Napel, Eugene Vorontsov, Lena Maier-Hein, M. Jorge Cardoso
Semantic segmentation of medical images aims to associate a pixel with a label in a medical image without human initialization.
no code implementations • 21 Feb 2019 • Jiachen Wang, Riqiang Gao, Yuankai Huo, Shunxing Bao, Yunxi Xiong, Sanja L. Antic, Travis J. Osterman, Pierre P. Massion, Bennett A. Landman
The results show that the AUC obtained from clinical demographics alone was 0. 635 while the attention network alone reached an accuracy of 0. 687.
no code implementations • 7 Jan 2019 • Yunxi Xiong, Yuankai Huo, Jiachen Wang, L. Taylor Davis, Maureen McHugo, Bennett A. Landman
Recently, we obtained a clinically acquired, multi-sequence MRI brain cohort with 1480 clinically acquired, de-identified brain MRI scans on 395 patients using seven different MRI protocols.
no code implementations • 10 Dec 2018 • Cailey I. Kerley, Yuankai Huo, Shikha Chaganti, Shunxing Bao, Mayur B. Patel, Bennett A. Landman
For instance, in a typical sample of clinical TBI imaging cohort, only ~15% of CT scans actually contain whole brain CT images suitable for volumetric brain analyses; the remaining are partial brain or non-brain images.
no code implementations • 26 Nov 2018 • Camilo Bermudez, William Rodriguez, Yuankai Huo, Allison E. Hainline, Rui Li, Robert Shults, Pierre D. DHaese, Peter E. Konrad, Benoit M. Dawant, Bennett A. Landman
We show an improvement in the classification of intraoperative stimulation coordinates as a positive response in reduction of symptoms with AUC of 0. 670 compared to a baseline registration-based approach, which achieves an AUC of 0. 627 (p < 0. 01).
no code implementations • 10 Nov 2018 • Yuankai Huo, James G. Terry, Jiachen Wang, Vishwesh Nath, Camilo Bermudez, Shunxing Bao, Prasanna Parvathaneni, J. Jeffery Carr, Bennett A. Landman
From the results, the proposed AID-Net achieved the superior performance on classification accuracy (0. 9272) and AUC (0. 9627).
no code implementations • 9 Nov 2018 • Yuankai Huo, Zhoubing Xu, Shunxing Bao, Camilo Bermudez, Hyeonsoo Moon, Prasanna Parvathaneni, Tamara K. Moyo, Michael R. Savona, Albert Assad, Richard G. Abramson, Bennett A. Landman
A clinically acquired cohort containing both T1-weighted (T1w) and T2-weighted (T2w) MRI splenomegaly scans was used to train and evaluate the performance of multi-atlas segmentation (MAS), 2D DCNN networks, and a 3D DCNN network.
1 code implementation • 15 Oct 2018 • Yuankai Huo, Zhoubing Xu, Hyeonsoo Moon, Shunxing Bao, Albert Assad, Tamara K. Moyo, Michael R. Savona, Richard G. Abramson, Bennett A. Landman
SynSeg-Net is trained by using (1) unpaired intensity images from source and target modalities, and (2) manual labels only from source modality.
no code implementations • 9 Oct 2018 • Vishwesh Nath, Prasanna Parvathaneni, Colin B. Hansen, Allison E. Hainline, Camilo Bermudez, Samuel Remedios, Justin A. Blaber, Kurt G. Schilling, Ilwoo Lyu, Vaibhav Janve, Yurui Gao, Iwona Stepniewska, Baxter P. Rogers, Allen T. Newton, L. Taylor Davis, Jeff Luci, Adam W. Anderson, Bennett A. Landman
Herein, we propose a data-driven tech-nique using a neural network design which exploits two categories of data.
no code implementations • 6 Jun 2018 • Yuankai Huo, Katherine Swett, Susan M. Resnick, Laurie E. Cutting, Bennett A. Landman
By indexing the dictionary, the whole brain probabilistic atlases adapt to each new subject quickly and can be used as spatial priors for visualization and processing.
no code implementations • 6 Jun 2018 • Lena Maier-Hein, Matthias Eisenmann, Annika Reinke, Sinan Onogur, Marko Stankovic, Patrick Scholz, Tal Arbel, Hrvoje Bogunovic, Andrew P. Bradley, Aaron Carass, Carolin Feldmann, Alejandro F. Frangi, Peter M. Full, Bram van Ginneken, Allan Hanbury, Katrin Honauer, Michal Kozubek, Bennett A. Landman, Keno März, Oskar Maier, Klaus Maier-Hein, Bjoern H. Menze, Henning Müller, Peter F. Neher, Wiro Niessen, Nasir Rajpoot, Gregory C. Sharp, Korsuk Sirinukunwattana, Stefanie Speidel, Christian Stock, Danail Stoyanov, Abdel Aziz Taha, Fons van der Sommen, Ching-Wei Wang, Marc-André Weber, Guoyan Zheng, Pierre Jannin, Annette Kopp-Schneider
International challenges have become the standard for validation of biomedical image analysis methods.
2 code implementations • 1 Jun 2018 • Yuankai Huo, Zhoubing Xu, Katherine Aboud, Prasanna Parvathaneni, Shunxing Bao, Camilo Bermudez, Susan M. Resnick, Laurie E. Cutting, Bennett A. Landman
Whole brain segmentation on a structural magnetic resonance imaging (MRI) is essential in non-invasive investigation for neuroanatomy.
no code implementations • 5 Jan 2018 • Camilo Bermudez, Andrew J. Plassard, Larry T. Davis, Allen T. Newton, Susan M. Resnick, Bennett A. Landman
Real and synthesized images were then assessed in a blinded manner by two imaging experts providing an image quality score of 1-5.
1 code implementation • 20 Dec 2017 • Yuankai Huo, Zhoubing Xu, Shunxing Bao, Albert Assad, Richard G. Abramson, Bennett A. Landman
Herein, we proposed a novel end-to-end synthesis and segmentation network (EssNet) to achieve the unpaired MRI to CT image synthesis and CT splenomegaly segmentation simultaneously without using manual labels on CT.
no code implementations • 2 Dec 2017 • Yuankai Huo, Shunxing Bao, Prasanna Parvathaneni, Bennett A. Landman
Herein, the MaCRUISE surface parcellation (MaCRUISEsp) method is proposed to perform the surface parcellation upon the inner, central and outer surfaces that are reconstructed from MaCRUISE.
1 code implementation • 2 Dec 2017 • Yuankai Huo, Zhoubing Xu, Shunxing Bao, Camilo Bermudez, Andrew J. Plassard, Jiaqi Liu, Yuang Yao, Albert Assad, Richard G. Abramson, Bennett A. Landman
However, variations in both size and shape of the spleen on MRI images may result in large false positive and false negative labeling when deploying DCNN based methods.
no code implementations • 29 Aug 2017 • Yuankai Huo, Susan M. Resnick, Bennett A. Landman
(2) The proposed algorithm is a longitudinal generalization of a lead-ing joint label fusion method (JLF) that has proven adaptable to a wide variety of applications.