Search Results for author: Daniel Rueckert

Found 271 papers, 118 papers with code

Attention-Gated Networks for Improving Ultrasound Scan Plane Detection

6 code implementations15 Apr 2018 Jo Schlemper, Ozan Oktay, Liang Chen, Jacqueline Matthew, Caroline Knight, Bernhard Kainz, Ben Glocker, Daniel Rueckert

We show that, when the base network has a high capacity, the incorporated attention mechanism can provide efficient object localisation while improving the overall performance.

DLTK: State of the Art Reference Implementations for Deep Learning on Medical Images

1 code implementation18 Nov 2017 Nick Pawlowski, Sofia Ira Ktena, Matthew C. H. Lee, Bernhard Kainz, Daniel Rueckert, Ben Glocker, Martin Rajchl

We present DLTK, a toolkit providing baseline implementations for efficient experimentation with deep learning methods on biomedical images.

Image Segmentation Semantic Segmentation

Convolutional Recurrent Neural Networks for Dynamic MR Image Reconstruction

4 code implementations5 Dec 2017 Chen Qin, Jo Schlemper, Jose Caballero, Anthony Price, Joseph V. Hajnal, Daniel Rueckert

In particular, the proposed architecture embeds the structure of the traditional iterative algorithms, efficiently modelling the recurrence of the iterative reconstruction stages by using recurrent hidden connections over such iterations.

Image Reconstruction Temporal Sequences

A Deep Cascade of Convolutional Neural Networks for Dynamic MR Image Reconstruction

4 code implementations8 Apr 2017 Jo Schlemper, Jose Caballero, Joseph V. Hajnal, Anthony Price, Daniel Rueckert

Firstly, we show that when each 2D image frame is reconstructed independently, the proposed method outperforms state-of-the-art 2D compressed sensing approaches such as dictionary learning-based MR image reconstruction, in terms of reconstruction error and reconstruction speed.

Dictionary Learning Image Reconstruction

Distance Metric Learning using Graph Convolutional Networks: Application to Functional Brain Networks

3 code implementations7 Mar 2017 Sofia Ira Ktena, Sarah Parisot, Enzo Ferrante, Martin Rajchl, Matthew Lee, Ben Glocker, Daniel Rueckert

Evaluating similarity between graphs is of major importance in several computer vision and pattern recognition problems, where graph representations are often used to model objects or interactions between elements.

Graph Similarity Metric Learning

Spectral Graph Convolutions for Population-based Disease Prediction

1 code implementation8 Mar 2017 Sarah Parisot, Sofia Ira Ktena, Enzo Ferrante, Matthew Lee, Ricardo Guerrerro Moreno, Ben Glocker, Daniel Rueckert

We demonstrate the potential of the method on the challenging ADNI and ABIDE databases, as a proof of concept of the benefit from integrating contextual information in classification tasks.

Disease Prediction

Automated cardiovascular magnetic resonance image analysis with fully convolutional networks

1 code implementation25 Oct 2017 Wenjia Bai, Matthew Sinclair, Giacomo Tarroni, Ozan Oktay, Martin Rajchl, Ghislain Vaillant, Aaron M. Lee, Nay Aung, Elena Lukaschuk, Mihir M. Sanghvi, Filip Zemrak, Kenneth Fung, Jose Miguel Paiva, Valentina Carapella, Young Jin Kim, Hideaki Suzuki, Bernhard Kainz, Paul M. Matthews, Steffen E. Petersen, Stefan K. Piechnik, Stefan Neubauer, Ben Glocker, Daniel Rueckert

By combining FCN with a large-scale annotated dataset, the proposed automated method achieves a high performance on par with human experts in segmenting the LV and RV on short-axis CMR images and the left atrium (LA) and right atrium (RA) on long-axis CMR images.

NeuroNet: Fast and Robust Reproduction of Multiple Brain Image Segmentation Pipelines

1 code implementation11 Jun 2018 Martin Rajchl, Nick Pawlowski, Daniel Rueckert, Paul M. Matthews, Ben Glocker

NeuroNet is a deep convolutional neural network mimicking multiple popular and state-of-the-art brain segmentation tools including FSL, SPM, and MALPEM.

Brain Image Segmentation Brain Segmentation +3

Interactive and Explainable Region-guided Radiology Report Generation

1 code implementation CVPR 2023 Tim Tanida, Philip Müller, Georgios Kaissis, Daniel Rueckert

While previous methods generate reports without the possibility of human intervention and with limited explainability, our method opens up novel clinical use cases through additional interactive capabilities and introduces a high degree of transparency and explainability.

Medical Report Generation

Physiology-based simulation of the retinal vasculature enables annotation-free segmentation of OCT angiographs

1 code implementation22 Jul 2022 Martin J. Menten, Johannes C. Paetzold, Alina Dima, Bjoern H. Menze, Benjamin Knier, Daniel Rueckert

Encouraged by our method's competitive quantitative and superior qualitative performance, we believe that it constitutes a versatile tool to advance the quantitative analysis of OCTA images.

Benchmarking Retinal Vessel Segmentation +2

Causality-inspired Single-source Domain Generalization for Medical Image Segmentation

1 code implementation24 Nov 2021 Cheng Ouyang, Chen Chen, Surui Li, Zeju Li, Chen Qin, Wenjia Bai, Daniel Rueckert

In this work, we investigate the single-source domain generalization problem: training a deep network that is robust to unseen domains, under the condition that training data is only available from one source domain, which is common in medical imaging applications.

Data Augmentation Domain Generalization +4

Best of Both Worlds: Multimodal Contrastive Learning with Tabular and Imaging Data

1 code implementation CVPR 2023 Paul Hager, Martin J. Menten, Daniel Rueckert

Medical datasets and especially biobanks, often contain extensive tabular data with rich clinical information in addition to images.

Contrastive Learning

Multiple Landmark Detection using Multi-Agent Reinforcement Learning

1 code implementation30 Jun 2019 Athanasios Vlontzos, Amir Alansary, Konstantinos Kamnitsas, Daniel Rueckert, Bernhard Kainz

We compare our approach with state-of-the-art architectures and achieve significantly better accuracy by reducing the detection error by 50%, while requiring fewer computational resources and time to train compared to the naive approach of training K agents separately.

Anatomy Multi-agent Reinforcement Learning +2

Fast Multiple Landmark Localisation Using a Patch-based Iterative Network

1 code implementation18 Jun 2018 Yuanwei Li, Amir Alansary, Juan J. Cerrolaza, Bishesh Khanal, Matthew Sinclair, Jacqueline Matthew, Chandni Gupta, Caroline Knight, Bernhard Kainz, Daniel Rueckert

PIN is computationally efficient since the inference stage only selectively samples a small number of patches in an iterative fashion rather than a dense sampling at every location in the volume.

Multi-Task Learning

Realistic Adversarial Data Augmentation for MR Image Segmentation

1 code implementation23 Jun 2020 Chen Chen, Chen Qin, Huaqi Qiu, Cheng Ouyang, Shuo Wang, Liang Chen, Giacomo Tarroni, Wenjia Bai, Daniel Rueckert

In this work, we propose an adversarial data augmentation method for training neural networks for medical image segmentation.

Data Augmentation Image Segmentation +3

$Σ$-net: Systematic Evaluation of Iterative Deep Neural Networks for Fast Parallel MR Image Reconstruction

1 code implementation18 Dec 2019 Kerstin Hammernik, Jo Schlemper, Chen Qin, Jinming Duan, Ronald M. Summers, Daniel Rueckert

Purpose: To systematically investigate the influence of various data consistency layers, (semi-)supervised learning and ensembling strategies, defined in a $\Sigma$-net, for accelerated parallel MR image reconstruction using deep learning.

Image Enhancement Image Reconstruction +1

Joint Learning of Motion Estimation and Segmentation for Cardiac MR Image Sequences

1 code implementation11 Jun 2018 Chen Qin, Wenjia Bai, Jo Schlemper, Steffen E. Petersen, Stefan K. Piechnik, Stefan Neubauer, Daniel Rueckert

Cardiac motion estimation and segmentation play important roles in quantitatively assessing cardiac function and diagnosing cardiovascular diseases.

Cardiac Segmentation Motion Estimation +2

dAUTOMAP: decomposing AUTOMAP to achieve scalability and enhance performance

1 code implementation24 Sep 2019 Jo Schlemper, Ilkay Oksuz, James R. Clough, Jinming Duan, Andrew P. King, Julia A. Schnabel, Joseph V. Hajnal, Daniel Rueckert

AUTOMAP is a promising generalized reconstruction approach, however, it is not scalable and hence the practicality is limited.

VS-Net: Variable splitting network for accelerated parallel MRI reconstruction

1 code implementation19 Jul 2019 Jinming Duan, Jo Schlemper, Chen Qin, Cheng Ouyang, Wenjia Bai, Carlo Biffi, Ghalib Bello, Ben Statton, Declan P. O'Regan, Daniel Rueckert

In this work, we propose a deep learning approach for parallel magnetic resonance imaging (MRI) reconstruction, termed a variable splitting network (VS-Net), for an efficient, high-quality reconstruction of undersampled multi-coil MR data.

MRI Reconstruction Rolling Shutter Correction

k-t NEXT: Dynamic MR Image Reconstruction Exploiting Spatio-temporal Correlations

1 code implementation22 Jul 2019 Chen Qin, Jo Schlemper, Jinming Duan, Gavin Seegoolam, Anthony Price, Joseph Hajnal, Daniel Rueckert

Experiments conducted on highly undersampled short-axis cardiac cine MRI scans demonstrate that our proposed method outperforms the current state-of-the-art dynamic MR reconstruction approaches both quantitatively and qualitatively.

Image Reconstruction

Complementary Time-Frequency Domain Networks for Dynamic Parallel MR Image Reconstruction

1 code implementation22 Dec 2020 Chen Qin, Jinming Duan, Kerstin Hammernik, Jo Schlemper, Thomas Küstner, René Botnar, Claudia Prieto, Anthony N. Price, Joseph V. Hajnal, Daniel Rueckert

The iterative model is embedded into a deep recurrent neural network which learns to recover the image via exploiting spatio-temporal redundancies in complementary domains.

De-aliasing Image Reconstruction

Cooperative Training and Latent Space Data Augmentation for Robust Medical Image Segmentation

2 code implementations2 Jul 2021 Chen Chen, Kerstin Hammernik, Cheng Ouyang, Chen Qin, Wenjia Bai, Daniel Rueckert

In this paper, we present a cooperative framework for training image segmentation models and a latent space augmentation method for generating hard examples.

Data Augmentation Image Reconstruction +4

MaxStyle: Adversarial Style Composition for Robust Medical Image Segmentation

1 code implementation2 Jun 2022 Chen Chen, Zeju Li, Cheng Ouyang, Matt Sinclair, Wenjia Bai, Daniel Rueckert

We propose a novel data augmentation framework called MaxStyle, which maximizes the effectiveness of style augmentation for model OOD performance.

Data Augmentation Image Segmentation +2

Adversarial and Perceptual Refinement for Compressed Sensing MRI Reconstruction

1 code implementation28 Jun 2018 Maximilian Seitzer, Guang Yang, Jo Schlemper, Ozan Oktay, Tobias Würfl, Vincent Christlein, Tom Wong, Raad Mohiaddin, David Firmin, Jennifer Keegan, Daniel Rueckert, Andreas Maier

In addition, we introduce a semantic interpretability score, measuring the visibility of the region of interest in both ground truth and reconstructed images, which allows us to objectively quantify the usefulness of the image quality for image post-processing and analysis.

MRI Reconstruction Open-Ended Question Answering

Joint Learning of Localized Representations from Medical Images and Reports

1 code implementation6 Dec 2021 Philip Müller, Georgios Kaissis, Congyu Zou, Daniel Rueckert

Contrastive learning has proven effective for pre-training image models on unlabeled data with promising results for tasks such as medical image classification.

Contrastive Learning Medical Image Classification +5

Surface Vision Transformers: Attention-Based Modelling applied to Cortical Analysis

1 code implementation30 Mar 2022 Simon Dahan, Abdulah Fawaz, Logan Z. J. Williams, Chunhui Yang, Timothy S. Coalson, Matthew F. Glasser, A. David Edwards, Daniel Rueckert, Emma C. Robinson

Motivated by the success of attention-modelling in computer vision, we translate convolution-free vision transformer approaches to surface data, to introduce a domain-agnostic architecture to study any surface data projected onto a spherical manifold.

Surface Vision Transformers: Flexible Attention-Based Modelling of Biomedical Surfaces

1 code implementation7 Apr 2022 Simon Dahan, Hao Xu, Logan Z. J. Williams, Abdulah Fawaz, Chunhui Yang, Timothy S. Coalson, Michelle C. Williams, David E. Newby, A. David Edwards, Matthew F. Glasser, Alistair A. Young, Daniel Rueckert, Emma C. Robinson

Results suggest that Surface Vision Transformers (SiT) demonstrate consistent improvement over geometric deep learning methods for brain age and fluid intelligence prediction and achieve comparable performance on calcium score classification to standard metrics used in clinical practice.

Classification Data Augmentation

Surface Analysis with Vision Transformers

1 code implementation31 May 2022 Simon Dahan, Logan Z. J. Williams, Abdulah Fawaz, Daniel Rueckert, Emma C. Robinson

The extension of convolutional neural networks (CNNs) to non-Euclidean geometries has led to multiple frameworks for studying manifolds.

The Multiscale Surface Vision Transformer

1 code implementation21 Mar 2023 Simon Dahan, Abdulah Fawaz, Mohamed A. Suliman, Mariana da Silva, Logan Z. J. Williams, Daniel Rueckert, Emma C. Robinson

Surface meshes are a favoured domain for representing structural and functional information on the human cortex, but their complex topology and geometry pose significant challenges for deep learning analysis.

Surface Masked AutoEncoder: Self-Supervision for Cortical Imaging Data

1 code implementation10 Aug 2023 Simon Dahan, Mariana da Silva, Daniel Rueckert, Emma C Robinson

By reconstructing surface data from a masked version of the input, the proposed method effectively models cortical structure to learn strong representations that translate to improved performance in downstream tasks.

SonoNet: Real-Time Detection and Localisation of Fetal Standard Scan Planes in Freehand Ultrasound

2 code implementations16 Dec 2016 Christian F. Baumgartner, Konstantinos Kamnitsas, Jacqueline Matthew, Tara P. Fletcher, Sandra Smith, Lisa M. Koch, Bernhard Kainz, Daniel Rueckert

In this paper, we propose a novel method based on convolutional neural networks which can automatically detect 13 fetal standard views in freehand 2D ultrasound data as well as provide a localisation of the fetal structures via a bounding box.

Anatomy Retrieval

Multi-Task Learning for Left Atrial Segmentation on GE-MRI

1 code implementation31 Oct 2018 Chen Chen, Wenjia Bai, Daniel Rueckert

Segmentation of the left atrium (LA) is crucial for assessing its anatomy in both pre-operative atrial fibrillation (AF) ablation planning and post-operative follow-up studies.

Anatomy General Classification +2

Ultrasound Video Summarization using Deep Reinforcement Learning

1 code implementation19 May 2020 Tianrui Liu, Qingjie Meng, Athanasios Vlontzos, Jeremy Tan, Daniel Rueckert, Bernhard Kainz

We show that our method is superior to alternative video summarization methods and that it preserves essential information required by clinical diagnostic standards.

reinforcement-learning Reinforcement Learning (RL) +1

CortexODE: Learning Cortical Surface Reconstruction by Neural ODEs

1 code implementation16 Feb 2022 Qiang Ma, Liu Li, Emma C. Robinson, Bernhard Kainz, Daniel Rueckert, Amir Alansary

Following the isosurface extraction step, two CortexODE models are trained to deform the initial surface to white matter and pial surfaces respectively.

Surface Reconstruction

Unsupervised Pathology Detection: A Deep Dive Into the State of the Art

1 code implementation1 Mar 2023 Ioannis Lagogiannis, Felix Meissen, Georgios Kaissis, Daniel Rueckert

Our experiments demonstrate that newly developed feature-modeling methods from the industrial and medical literature achieve increased performance compared to previous work and set the new SOTA in a variety of modalities and datasets.

Unsupervised Anomaly Detection

Biomechanics-informed Neural Networks for Myocardial Motion Tracking in MRI

1 code implementation8 Jun 2020 Chen Qin, Shuo Wang, Chen Chen, Huaqi Qiu, Wenjia Bai, Daniel Rueckert

The learnt VAE regulariser then can be coupled with any deep learning based registration network to regularise the solution space to be biomechanically plausible.

Image Registration

A skeletonization algorithm for gradient-based optimization

1 code implementation ICCV 2023 Martin J. Menten, Johannes C. Paetzold, Veronika A. Zimmer, Suprosanna Shit, Ivan Ezhov, Robbie Holland, Monika Probst, Julia A. Schnabel, Daniel Rueckert

Finally, we demonstrate the utility of our algorithm by integrating it with two medical image processing applications that use gradient-based optimization: deep-learning-based blood vessel segmentation, and multimodal registration of the mandible in computed tomography and magnetic resonance images.

Benchmarking

Predicting Slice-to-Volume Transformation in Presence of Arbitrary Subject Motion

1 code implementation28 Feb 2017 Benjamin Hou, Amir Alansary, Steven McDonagh, Alice Davidson, Mary Rutherford, Jo V. Hajnal, Daniel Rueckert, Ben Glocker, Bernhard Kainz

Our approach is attractive in challenging imaging scenarios, where significant subject motion complicates reconstruction performance of 3D volumes from 2D slice data.

Image Registration Motion Compensation +1

Attention Gated Networks: Learning to Leverage Salient Regions in Medical Images

2 code implementations22 Aug 2018 Jo Schlemper, Ozan Oktay, Michiel Schaap, Mattias Heinrich, Bernhard Kainz, Ben Glocker, Daniel Rueckert

AGs can be easily integrated into standard CNN models such as VGG or U-Net architectures with minimal computational overhead while increasing the model sensitivity and prediction accuracy.

Computational Efficiency General Classification +2

Improving Phenotype Prediction using Long-Range Spatio-Temporal Dynamics of Functional Connectivity

1 code implementation7 Sep 2021 Simon Dahan, Logan Z. J. Williams, Daniel Rueckert, Emma C. Robinson

Results show a prediction accuracy of 94. 4% for sex classification (an increase of 6. 2% compared to other methods), and an improvement of correlation with fluid intelligence of 0. 325 vs 0. 144, relative to a baseline model that encodes space and time separately.

Action Recognition Skeleton Based Action Recognition

Single-subject Multi-contrast MRI Super-resolution via Implicit Neural Representations

1 code implementation27 Mar 2023 Julian McGinnis, Suprosanna Shit, Hongwei Bran Li, Vasiliki Sideri-Lampretsa, Robert Graf, Maik Dannecker, Jiazhen Pan, Nil Stolt Ansó, Mark Mühlau, Jan S. Kirschke, Daniel Rueckert, Benedikt Wiestler

Clinical routine and retrospective cohorts commonly include multi-parametric Magnetic Resonance Imaging; however, they are mostly acquired in different anisotropic 2D views due to signal-to-noise-ratio and scan-time constraints.

Super-Resolution

PialNN: A Fast Deep Learning Framework for Cortical Pial Surface Reconstruction

1 code implementation6 Sep 2021 Qiang Ma, Emma C. Robinson, Bernhard Kainz, Daniel Rueckert, Amir Alansary

Traditional cortical surface reconstruction is time consuming and limited by the resolution of brain Magnetic Resonance Imaging (MRI).

Surface Reconstruction

Link Prediction for Flow-Driven Spatial Networks

1 code implementation25 Mar 2023 Bastian Wittmann, Johannes C. Paetzold, Chinmay Prabhakar, Daniel Rueckert, Bjoern Menze

In this work, we focus on link prediction for flow-driven spatial networks, which are embedded in a Euclidean space and relate to physical exchange and transportation processes (e. g., blood flow in vessels or traffic flow in road networks).

Link Prediction

Unsupervised Anomaly Localization with Structural Feature-Autoencoders

1 code implementation23 Aug 2022 Felix Meissen, Johannes Paetzold, Georgios Kaissis, Daniel Rueckert

Most commonly, the anomaly detection model generates a "normal" version of an input image, and the pixel-wise $l^p$-difference of the two is used to localize anomalies.

Unsupervised Anomaly Detection

NISF: Neural Implicit Segmentation Functions

1 code implementation15 Sep 2023 Nil Stolt-Ansó, Julian McGinnis, Jiazhen Pan, Kerstin Hammernik, Daniel Rueckert

Approaches that rely on convolutional neural networks (CNNs) are limited to grid-like inputs and not easily applicable to sparse or partial measurements.

Cardiac Segmentation Image Segmentation +2

Towards Universal Unsupervised Anomaly Detection in Medical Imaging

1 code implementation19 Jan 2024 Cosmin I. Bercea, Benedikt Wiestler, Daniel Rueckert, Julia A. Schnabel

Our unsupervised anomaly detection approach may enhance diagnostic accuracy in medical imaging by identifying a broader range of unknown pathologies.

Unsupervised Anomaly Detection

Geometric Deep Learning for Post-Menstrual Age Prediction based on the Neonatal White Matter Cortical Surface

1 code implementation13 Aug 2020 Vitalis Vosylius, Andy Wang, Cemlyn Waters, Alexey Zakharov, Francis Ward, Loic Le Folgoc, John Cupitt, Antonios Makropoulos, Andreas Schuh, Daniel Rueckert, Amir Alansary

In this paper, we propose a novel approach to predict the post-menstrual age (PA) at scan, using techniques from geometric deep learning, based on the neonatal white matter cortical surface.

Differentially Private Graph Classification with GNNs

1 code implementation5 Feb 2022 Tamara T. Mueller, Johannes C. Paetzold, Chinmay Prabhakar, Dmitrii Usynin, Daniel Rueckert, Georgios Kaissis

In this work, we introduce differential privacy for graph-level classification, one of the key applications of machine learning on graphs.

BIG-bench Machine Learning Graph Classification

CHeart: A Conditional Spatio-Temporal Generative Model for Cardiac Anatomy

1 code implementation30 Jan 2023 Mengyun Qiao, Shuo Wang, Huaqi Qiu, Antonio de Marvao, Declan P. O'Regan, Daniel Rueckert, Wenjia Bai

Two key questions in cardiac image analysis are to assess the anatomy and motion of the heart from images; and to understand how they are associated with non-imaging clinical factors such as gender, age and diseases.

Anatomy Image Segmentation +1

Challenging Current Semi-Supervised Anomaly Segmentation Methods for Brain MRI

1 code implementation13 Sep 2021 Felix Meissen, Georgios Kaissis, Daniel Rueckert

In this work, we tackle the problem of Semi-Supervised Anomaly Segmentation (SAS) in Magnetic Resonance Images (MRI) of the brain, which is the task of automatically identifying pathologies in brain images.

Anomaly Detection Segmentation

Generative Myocardial Motion Tracking via Latent Space Exploration with Biomechanics-informed Prior

1 code implementation8 Jun 2022 Chen Qin, Shuo Wang, Chen Chen, Wenjia Bai, Daniel Rueckert

In contrast to most existing approaches which impose explicit generic regularization such as smoothness, in this work we propose a novel method that can implicitly learn an application-specific biomechanics-informed prior and embed it into a neural network-parameterized transformation model.

Image Registration

Conditional Temporal Attention Networks for Neonatal Cortical Surface Reconstruction

1 code implementation21 Jul 2023 Qiang Ma, Liu Li, Vanessa Kyriakopoulou, Joseph Hajnal, Emma C. Robinson, Bernhard Kainz, Daniel Rueckert

The importance of each SVF, which is estimated by learned attention maps, is conditioned on the age of the neonates and varies with the time step of integration.

Surface Reconstruction

Identifying the Best Machine Learning Algorithms for Brain Tumor Segmentation, Progression Assessment, and Overall Survival Prediction in the BRATS Challenge

1 code implementation5 Nov 2018 Spyridon Bakas, Mauricio Reyes, Andras Jakab, Stefan Bauer, Markus Rempfler, Alessandro Crimi, Russell Takeshi Shinohara, Christoph Berger, Sung Min Ha, Martin Rozycki, Marcel Prastawa, Esther Alberts, Jana Lipkova, John Freymann, Justin Kirby, Michel Bilello, Hassan Fathallah-Shaykh, Roland Wiest, Jan Kirschke, Benedikt Wiestler, Rivka Colen, Aikaterini Kotrotsou, Pamela Lamontagne, Daniel Marcus, Mikhail Milchenko, Arash Nazeri, Marc-Andre Weber, Abhishek Mahajan, Ujjwal Baid, Elizabeth Gerstner, Dongjin Kwon, Gagan Acharya, Manu Agarwal, Mahbubul Alam, Alberto Albiol, Antonio Albiol, Francisco J. Albiol, Varghese Alex, Nigel Allinson, Pedro H. A. Amorim, Abhijit Amrutkar, Ganesh Anand, Simon Andermatt, Tal Arbel, Pablo Arbelaez, Aaron Avery, Muneeza Azmat, Pranjal B., W Bai, Subhashis Banerjee, Bill Barth, Thomas Batchelder, Kayhan Batmanghelich, Enzo Battistella, Andrew Beers, Mikhail Belyaev, Martin Bendszus, Eze Benson, Jose Bernal, Halandur Nagaraja Bharath, George Biros, Sotirios Bisdas, James Brown, Mariano Cabezas, Shilei Cao, Jorge M. Cardoso, Eric N Carver, Adrià Casamitjana, Laura Silvana Castillo, Marcel Catà, Philippe Cattin, Albert Cerigues, Vinicius S. Chagas, Siddhartha Chandra, Yi-Ju Chang, Shiyu Chang, Ken Chang, Joseph Chazalon, Shengcong Chen, Wei Chen, Jefferson W. Chen, Zhaolin Chen, Kun Cheng, Ahana Roy Choudhury, Roger Chylla, Albert Clérigues, Steven Colleman, Ramiro German Rodriguez Colmeiro, Marc Combalia, Anthony Costa, Xiaomeng Cui, Zhenzhen Dai, Lutao Dai, Laura Alexandra Daza, Eric Deutsch, Changxing Ding, Chao Dong, Shidu Dong, Wojciech Dudzik, Zach Eaton-Rosen, Gary Egan, Guilherme Escudero, Théo Estienne, Richard Everson, Jonathan Fabrizio, Yong Fan, Longwei Fang, Xue Feng, Enzo Ferrante, Lucas Fidon, Martin Fischer, Andrew P. French, Naomi Fridman, Huan Fu, David Fuentes, Yaozong Gao, Evan Gates, David Gering, Amir Gholami, Willi Gierke, Ben Glocker, Mingming Gong, Sandra González-Villá, T. Grosges, Yuanfang Guan, Sheng Guo, Sudeep Gupta, Woo-Sup Han, Il Song Han, Konstantin Harmuth, Huiguang He, Aura Hernández-Sabaté, Evelyn Herrmann, Naveen Himthani, Winston Hsu, Cheyu Hsu, Xiaojun Hu, Xiaobin Hu, Yan Hu, Yifan Hu, Rui Hua, Teng-Yi Huang, Weilin Huang, Sabine Van Huffel, Quan Huo, Vivek HV, Khan M. Iftekharuddin, Fabian Isensee, Mobarakol Islam, Aaron S. Jackson, Sachin R. Jambawalikar, Andrew Jesson, Weijian Jian, Peter Jin, V Jeya Maria Jose, Alain Jungo, B Kainz, Konstantinos Kamnitsas, Po-Yu Kao, Ayush Karnawat, Thomas Kellermeier, Adel Kermi, Kurt Keutzer, Mohamed Tarek Khadir, Mahendra Khened, Philipp Kickingereder, Geena Kim, Nik King, Haley Knapp, Urspeter Knecht, Lisa Kohli, Deren Kong, Xiangmao Kong, Simon Koppers, Avinash Kori, Ganapathy Krishnamurthi, Egor Krivov, Piyush Kumar, Kaisar Kushibar, Dmitrii Lachinov, Tryphon Lambrou, Joon Lee, Chengen Lee, Yuehchou Lee, M Lee, Szidonia Lefkovits, Laszlo Lefkovits, James Levitt, Tengfei Li, Hongwei Li, Hongyang Li, Xiaochuan Li, Yuexiang Li, Heng Li, Zhenye Li, Xiaoyu Li, Zeju Li, Xiaogang Li, Wenqi Li, Zheng-Shen Lin, Fengming Lin, Pietro Lio, Chang Liu, Boqiang Liu, Xiang Liu, Mingyuan Liu, Ju Liu, Luyan Liu, Xavier Llado, Marc Moreno Lopez, Pablo Ribalta Lorenzo, Zhentai Lu, Lin Luo, Zhigang Luo, Jun Ma, Kai Ma, Thomas Mackie, Anant Madabushi, Issam Mahmoudi, Klaus H. Maier-Hein, Pradipta Maji, CP Mammen, Andreas Mang, B. S. Manjunath, Michal Marcinkiewicz, S McDonagh, Stephen McKenna, Richard McKinley, Miriam Mehl, Sachin Mehta, Raghav Mehta, Raphael Meier, Christoph Meinel, Dorit Merhof, Craig Meyer, Robert Miller, Sushmita Mitra, Aliasgar Moiyadi, David Molina-Garcia, Miguel A. B. Monteiro, Grzegorz Mrukwa, Andriy Myronenko, Jakub Nalepa, Thuyen Ngo, Dong Nie, Holly Ning, Chen Niu, Nicholas K Nuechterlein, Eric Oermann, Arlindo Oliveira, Diego D. C. Oliveira, Arnau Oliver, Alexander F. I. Osman, Yu-Nian Ou, Sebastien Ourselin, Nikos Paragios, Moo Sung Park, Brad Paschke, J. Gregory Pauloski, Kamlesh Pawar, Nick Pawlowski, Linmin Pei, Suting Peng, Silvio M. Pereira, Julian Perez-Beteta, Victor M. Perez-Garcia, Simon Pezold, Bao Pham, Ashish Phophalia, Gemma Piella, G. N. Pillai, Marie Piraud, Maxim Pisov, Anmol Popli, Michael P. Pound, Reza Pourreza, Prateek Prasanna, Vesna Prkovska, Tony P. Pridmore, Santi Puch, Élodie Puybareau, Buyue Qian, Xu Qiao, Martin Rajchl, Swapnil Rane, Michael Rebsamen, Hongliang Ren, Xuhua Ren, Karthik Revanuru, Mina Rezaei, Oliver Rippel, Luis Carlos Rivera, Charlotte Robert, Bruce Rosen, Daniel Rueckert, Mohammed Safwan, Mostafa Salem, Joaquim Salvi, Irina Sanchez, Irina Sánchez, Heitor M. Santos, Emmett Sartor, Dawid Schellingerhout, Klaudius Scheufele, Matthew R. Scott, Artur A. Scussel, Sara Sedlar, Juan Pablo Serrano-Rubio, N. Jon Shah, Nameetha Shah, Mazhar Shaikh, B. Uma Shankar, Zeina Shboul, Haipeng Shen, Dinggang Shen, Linlin Shen, Haocheng Shen, Varun Shenoy, Feng Shi, Hyung Eun Shin, Hai Shu, Diana Sima, M Sinclair, Orjan Smedby, James M. Snyder, Mohammadreza Soltaninejad, Guidong Song, Mehul Soni, Jean Stawiaski, Shashank Subramanian, Li Sun, Roger Sun, Jiawei Sun, Kay Sun, Yu Sun, Guoxia Sun, Shuang Sun, Yannick R Suter, Laszlo Szilagyi, Sanjay Talbar, DaCheng Tao, Zhongzhao Teng, Siddhesh Thakur, Meenakshi H Thakur, Sameer Tharakan, Pallavi Tiwari, Guillaume Tochon, Tuan Tran, Yuhsiang M. Tsai, Kuan-Lun Tseng, Tran Anh Tuan, Vadim Turlapov, Nicholas Tustison, Maria Vakalopoulou, Sergi Valverde, Rami Vanguri, Evgeny Vasiliev, Jonathan Ventura, Luis Vera, Tom Vercauteren, C. A. Verrastro, Lasitha Vidyaratne, Veronica Vilaplana, Ajeet Vivekanandan, Qian Wang, Chiatse J. Wang, Wei-Chung Wang, Duo Wang, Ruixuan Wang, Yuanyuan Wang, Chunliang Wang, Guotai Wang, Ning Wen, Xin Wen, Leon Weninger, Wolfgang Wick, Shaocheng Wu, Qiang Wu, Yihong Wu, Yong Xia, Yanwu Xu, Xiaowen Xu, Peiyuan Xu, Tsai-Ling Yang, Xiaoping Yang, Hao-Yu Yang, Junlin Yang, Haojin Yang, Guang Yang, Hongdou Yao, Xujiong Ye, Changchang Yin, Brett Young-Moxon, Jinhua Yu, Xiangyu Yue, Songtao Zhang, Angela Zhang, Kun Zhang, Xue-jie Zhang, Lichi Zhang, Xiaoyue Zhang, Yazhuo Zhang, Lei Zhang, Jian-Guo Zhang, Xiang Zhang, Tianhao Zhang, Sicheng Zhao, Yu Zhao, Xiaomei Zhao, Liang Zhao, Yefeng Zheng, Liming Zhong, Chenhong Zhou, Xiaobing Zhou, Fan Zhou, Hongtu Zhu, Jin Zhu, Ying Zhuge, Weiwei Zong, Jayashree Kalpathy-Cramer, Keyvan Farahani, Christos Davatzikos, Koen van Leemput, Bjoern Menze

This study assesses the state-of-the-art machine learning (ML) methods used for brain tumor image analysis in mpMRI scans, during the last seven instances of the International Brain Tumor Segmentation (BraTS) challenge, i. e., 2012-2018.

Brain Tumor Segmentation Survival Prediction +1

Differentially private federated deep learning for multi-site medical image segmentation

1 code implementation6 Jul 2021 Alexander Ziller, Dmitrii Usynin, Nicolas Remerscheid, Moritz Knolle, Marcus Makowski, Rickmer Braren, Daniel Rueckert, Georgios Kaissis

The application of PTs to FL in medical imaging and the trade-offs between privacy guarantees and model utility, the ramifications on training performance and the susceptibility of the final models to attacks have not yet been conclusively investigated.

Federated Learning Image Segmentation +4

Robust Detection Outcome: A Metric for Pathology Detection in Medical Images

1 code implementation3 Mar 2023 Felix Meissen, Philip Müller, Georgios Kaissis, Daniel Rueckert

To tackle this problem, we propose Robust Detection Outcome (RoDeO); a novel metric for evaluating algorithms for pathology detection in medical images, especially in chest X-rays.

object-detection Object Detection

Multimodal brain age estimation using interpretable adaptive population-graph learning

1 code implementation10 Jul 2023 Kyriaki-Margarita Bintsi, Vasileios Baltatzis, Rolandos Alexandros Potamias, Alexander Hammers, Daniel Rueckert

We further show that the assigned attention scores indicate that there are both imaging and non-imaging phenotypes that are informative for brain age estimation and are in agreement with the relevant literature.

Age Estimation graph construction +1

Improving the generalizability of convolutional neural network-based segmentation on CMR images

1 code implementation2 Jul 2019 Chen Chen, Wenjia Bai, Rhodri H. Davies, Anish N. Bhuva, Charlotte Manisty, James C. Moon, Nay Aung, Aaron M. Lee, Mihir M. Sanghvi, Kenneth Fung, Jose Miguel Paiva, Steffen E. Petersen, Elena Lukaschuk, Stefan K. Piechnik, Stefan Neubauer, Daniel Rueckert

We demonstrate that a neural network trained on a single-site single-scanner dataset from the UK Biobank can be successfully applied to segmenting cardiac MR images across different sites and different scanners without substantial loss of accuracy.

Image Segmentation Segmentation +1

3D Arterial Segmentation via Single 2D Projections and Depth Supervision in Contrast-Enhanced CT Images

1 code implementation15 Sep 2023 Alina F. Dima, Veronika A. Zimmer, Martin J. Menten, Hongwei Bran Li, Markus Graf, Tristan Lemke, Philipp Raffler, Robert Graf, Jan S. Kirschke, Rickmer Braren, Daniel Rueckert

In this work, we propose a novel method to segment the 3D peripancreatic arteries solely from one annotated 2D projection per training image with depth supervision.

Segmentation

Detecting Outliers with Poisson Image Interpolation

1 code implementation6 Jul 2021 Jeremy Tan, Benjamin Hou, Thomas Day, John Simpson, Daniel Rueckert, Bernhard Kainz

We propose an alternative to image reconstruction-based and image embedding-based methods and propose a new self-supervised method to tackle pathological anomaly detection.

Anomaly Detection Image Reconstruction

AutoSeg -- Steering the Inductive Biases for Automatic Pathology Segmentation

1 code implementation24 Jan 2022 Felix Meissen, Georgios Kaissis, Daniel Rueckert

In medical imaging, un-, semi-, or self-supervised pathology detection is often approached with anomaly- or out-of-distribution detection methods, whose inductive biases are not intentionally directed towards detecting pathologies, and are therefore sub-optimal for this task.

Out-of-Distribution Detection

On the Pitfalls of Using the Residual Error as Anomaly Score

1 code implementation8 Feb 2022 Felix Meissen, Benedikt Wiestler, Georgios Kaissis, Daniel Rueckert

Many current state-of-the-art methods for anomaly localization in medical images rely on calculating a residual image between a potentially anomalous input image and its "healthy" reconstruction.

SmoothNets: Optimizing CNN architecture design for differentially private deep learning

1 code implementation9 May 2022 Nicolas W. Remerscheid, Alexander Ziller, Daniel Rueckert, Georgios Kaissis

The arguably most widely employed algorithm to train deep neural networks with Differential Privacy is DPSGD, which requires clipping and noising of per-sample gradients.

Image Classification with Differential Privacy

Unsupervised Cross-domain Image Classification by Distance Metric Guided Feature Alignment

1 code implementation19 Aug 2020 Qingjie Meng, Daniel Rueckert, Bernhard Kainz

The proposed MetFA method explicitly and directly learns the latent representation without using domain adversarial training.

General Classification Image Classification +1

Personalized Federated Deep Learning for Pain Estimation From Face Images

1 code implementation12 Jan 2021 Ognjen Rudovic, Nicolas Tobis, Sebastian Kaltwang, Björn Schuller, Daniel Rueckert, Jeffrey F. Cohn, Rosalind W. Picard

A potential approach to tackling this is Federated Learning (FL), which enables multiple parties to collaboratively learn a shared prediction model by using parameters of locally trained models while keeping raw training data locally.

Federated Learning

Embedding Gradient-based Optimization in Image Registration Networks

1 code implementation7 Dec 2021 Huaqi Qiu, Kerstin Hammernik, Chen Qin, Chen Chen, Daniel Rueckert

Deep learning (DL) image registration methods amortize the costly pair-wise iterative optimization by training deep neural networks to predict the optimal transformation in one fast forward-pass.

Image Reconstruction Image Registration

Placenta Segmentation in Ultrasound Imaging: Addressing Sources of Uncertainty and Limited Field-of-View

1 code implementation29 Jun 2022 Veronika A. Zimmer, Alberto Gomez, Emily Skelton, Robert Wright, Gavin Wheeler, Shujie Deng, Nooshin Ghavami, Karen Lloyd, Jacqueline Matthew, Bernhard Kainz, Daniel Rueckert, Joseph V. Hajnal, Julia A. Schnabel

Automatic segmentation of the placenta in fetal ultrasound (US) is challenging due to the (i) high diversity of placenta appearance, (ii) the restricted quality in US resulting in highly variable reference annotations, and (iii) the limited field-of-view of US prohibiting whole placenta assessment at late gestation.

Image Segmentation Multi-Task Learning +3

Generative Modelling of the Ageing Heart with Cross-Sectional Imaging and Clinical Data

1 code implementation28 Aug 2022 Mengyun Qiao, Berke Doga Basaran, Huaqi Qiu, Shuo Wang, Yi Guo, Yuanyuan Wang, Paul M. Matthews, Daniel Rueckert, Wenjia Bai

Understanding the morphological and functional changes of the heart during ageing is a key scientific question, the answer to which will help us define important risk factors of cardiovascular disease and monitor disease progression.

Anatomy

Anatomy-Driven Pathology Detection on Chest X-rays

1 code implementation5 Sep 2023 Philip Müller, Felix Meissen, Johannes Brandt, Georgios Kaissis, Daniel Rueckert

Pathology detection and delineation enables the automatic interpretation of medical scans such as chest X-rays while providing a high level of explainability to support radiologists in making informed decisions.

Anatomy Multiple Instance Learning +2

Interpretable 2D Vision Models for 3D Medical Images

1 code implementation13 Jul 2023 Alexander Ziller, Ayhan Can Erdur, Marwa Trigui, Alp Güvenir, Tamara T. Mueller, Philip Müller, Friederike Jungmann, Johannes Brandt, Jan Peeken, Rickmer Braren, Daniel Rueckert, Georgios Kaissis

Training Artificial Intelligence (AI) models on 3D images presents unique challenges compared to the 2D case: Firstly, the demand for computational resources is significantly higher, and secondly, the availability of large datasets for pre-training is often limited, impeding training success.

Diffusion Models with Implicit Guidance for Medical Anomaly Detection

1 code implementation13 Mar 2024 Cosmin I. Bercea, Benedikt Wiestler, Daniel Rueckert, Julia A. Schnabel

Diffusion models have advanced unsupervised anomaly detection by improving the transformation of pathological images into pseudo-healthy equivalents.

Specificity Unsupervised Anomaly Detection

Representation Disentanglement for Multi-task Learning with application to Fetal Ultrasound

1 code implementation21 Aug 2019 Qingjie Meng, Nick Pawlowski, Daniel Rueckert, Bernhard Kainz

These entangled image properties lead to a semantically redundant feature encoding for the relevant task and thus lead to poor generalization of deep learning algorithms.

Anatomy Disentanglement +1

Weakly Supervised Object Detection in Chest X-Rays with Differentiable ROI Proposal Networks and Soft ROI Pooling

1 code implementation19 Feb 2024 Philip Müller, Felix Meissen, Georgios Kaissis, Daniel Rueckert

Weakly supervised object detection (WSup-OD) increases the usefulness and interpretability of image classification algorithms without requiring additional supervision.

Image Classification Multiple Instance Learning +2

Training deep segmentation networks on texture-encoded input: application to neuroimaging of the developing neonatal brain

1 code implementation MIDL 2019 Ahmed E. Fetit, John Cupitt, Turkay Kart, Daniel Rueckert

Standard practice for using convolutional neural networks (CNNs) in semantic segmentation tasks assumes that the image intensities are directly used for training and inference.

Segmentation Semantic Segmentation

Improved post-hoc probability calibration for out-of-domain MRI segmentation

1 code implementation4 Aug 2022 Cheng Ouyang, Shuo Wang, Chen Chen, Zeju Li, Wenjia Bai, Bernhard Kainz, Daniel Rueckert

In image segmentation, well-calibrated probabilities allow radiologists to identify regions where model-predicted segmentations are unreliable.

Image Segmentation MRI segmentation +2

Physics-Aware Motion Simulation for T2*-Weighted Brain MRI

1 code implementation20 Mar 2023 Hannah Eichhorn, Kerstin Hammernik, Veronika Spieker, Samira M. Epp, Daniel Rueckert, Christine Preibisch, Julia A. Schnabel

As T2*-weighted MRI is highly sensitive to motion-related changes in magnetic field inhomogeneities, it is of utmost importance to include physics information in the simulation.

Line Detection

A Comparative Study of Population-Graph Construction Methods and Graph Neural Networks for Brain Age Regression

1 code implementation26 Sep 2023 Kyriaki-Margarita Bintsi, Tamara T. Mueller, Sophie Starck, Vasileios Baltatzis, Alexander Hammers, Daniel Rueckert

We conclude that static graph construction approaches are potentially insufficient for the task of brain age estimation and make recommendations for alternative research directions.

Age Estimation Graph Attention +1

TopCoW: Benchmarking Topology-Aware Anatomical Segmentation of the Circle of Willis (CoW) for CTA and MRA

1 code implementation29 Dec 2023 Kaiyuan Yang, Fabio Musio, Yihui Ma, Norman Juchler, Johannes C. Paetzold, Rami Al-Maskari, Luciano Höher, Hongwei Bran Li, Ibrahim Ethem Hamamci, Anjany Sekuboyina, Suprosanna Shit, Houjing Huang, Diana Waldmannstetter, Florian Kofler, Fernando Navarro, Martin Menten, Ivan Ezhov, Daniel Rueckert, Iris Vos, Ynte Ruigrok, Birgitta Velthuis, Hugo Kuijf, Julien Hämmerli, Catherine Wurster, Philippe Bijlenga, Laura Westphal, Jeroen Bisschop, Elisa Colombo, Hakim Baazaoui, Andrew Makmur, James Hallinan, Bene Wiestler, Jan S. Kirschke, Roland Wiest, Emmanuel Montagnon, Laurent Letourneau-Guillon, Adrian Galdran, Francesco Galati, Daniele Falcetta, Maria A. Zuluaga, Chaolong Lin, Haoran Zhao, Zehan Zhang, Sinyoung Ra, Jongyun Hwang, HyunJin Park, Junqiang Chen, Marek Wodzinski, Henning Müller, Pengcheng Shi, Wei Liu, Ting Ma, Cansu Yalçin, Rachika E. Hamadache, Joaquim Salvi, Xavier Llado, Uma Maria Lal-Trehan Estrada, Valeriia Abramova, Luca Giancardo, Arnau Oliver, Jialu Liu, Haibin Huang, Yue Cui, Zehang Lin, Yusheng Liu, Shunzhi Zhu, Tatsat R. Patel, Vincent M. Tutino, Maysam Orouskhani, Huayu Wang, Mahmud Mossa-Basha, Chengcheng Zhu, Maximilian R. Rokuss, Yannick Kirchhoff, Nico Disch, Julius Holzschuh, Fabian Isensee, Klaus Maier-Hein, Yuki Sato, Sven Hirsch, Susanne Wegener, Bjoern Menze

The TopCoW dataset was the first public dataset with voxel-level annotations for thirteen possible CoW vessel components, enabled by virtual-reality (VR) technology.

Anatomy Benchmarking +1

Intensity-based 3D motion correction for cardiac MR images

1 code implementation31 Mar 2024 Nil Stolt-Ansó, Vasiliki Sideri-Lampretsa, Maik Dannecker, Daniel Rueckert

Cardiac magnetic resonance (CMR) image acquisition requires subjects to hold their breath while 2D cine images are acquired.

Anatomy Position

Semi-Supervised Learning via Compact Latent Space Clustering

no code implementations ICML 2018 Konstantinos Kamnitsas, Daniel C. Castro, Loic Le Folgoc, Ian Walker, Ryutaro Tanno, Daniel Rueckert, Ben Glocker, Antonio Criminisi, Aditya Nori

We present a novel cost function for semi-supervised learning of neural networks that encourages compact clustering of the latent space to facilitate separation.

Clustering

Graph Saliency Maps through Spectral Convolutional Networks: Application to Sex Classification with Brain Connectivity

no code implementations5 Jun 2018 Salim Arslan, Sofia Ira Ktena, Ben Glocker, Daniel Rueckert

Graph convolutional networks (GCNs) allow to apply traditional convolution operations in non-Euclidean domains, where data are commonly modelled as irregular graphs.

General Classification

Learning-Based Quality Control for Cardiac MR Images

no code implementations25 Mar 2018 Giacomo Tarroni, Ozan Oktay, Wenjia Bai, Andreas Schuh, Hideaki Suzuki, Jonathan Passerat-Palmbach, Antonio de Marvao, Declan P. O'Regan, Stuart Cook, Ben Glocker, Paul M. Matthews, Daniel Rueckert

The results show the capability of the proposed pipeline to correctly detect incomplete or corrupted scans (e. g. on UK Biobank, sensitivity and specificity respectively 88% and 99% for heart coverage estimation, 85% and 95% for motion detection), allowing their exclusion from the analysed dataset or the triggering of a new acquisition.

Motion Detection Specificity

3D Reconstruction in Canonical Co-ordinate Space from Arbitrarily Oriented 2D Images

no code implementations19 Sep 2017 Benjamin Hou, Bishesh Khanal, Amir Alansary, Steven McDonagh, Alice Davidson, Mary Rutherford, Jo V. Hajnal, Daniel Rueckert, Ben Glocker, Bernhard Kainz

We extensively evaluate the effectiveness of our approach quantitatively on simulated Magnetic Resonance Imaging (MRI), fetal brain imagery with synthetic motion and further demonstrate qualitative results on real fetal MRI data where our method is integrated into a full reconstruction and motion compensation pipeline.

3D Reconstruction Image Reconstruction +2

Is human face processing a feature- or pattern-based task? Evidence using a unified computational method driven by eye movements

no code implementations4 Sep 2017 Carlos E. Thomaz, Vagner Amaral, Gilson A. Giraldi, Duncan F. Gillies, Daniel Rueckert

Research on human face processing using eye movements has provided evidence that we recognize face images successfully focusing our visual attention on a few inner facial regions, mainly on the eyes, nose and mouth.

Facial Expression Recognition Facial Expression Recognition (FER)

Employing Weak Annotations for Medical Image Analysis Problems

no code implementations21 Aug 2017 Martin Rajchl, Lisa M. Koch, Christian Ledig, Jonathan Passerat-Palmbach, Kazunari Misawa, Kensaku MORI, Daniel Rueckert

To efficiently establish training databases for machine learning methods, collaborative and crowdsourcing platforms have been investigated to collectively tackle the annotation effort.

Computed Tomography (CT) Liver Segmentation +1

Exploring Heritability of Functional Brain Networks with Inexact Graph Matching

no code implementations29 Mar 2017 Sofia Ira Ktena, Salim Arslan, Sarah Parisot, Daniel Rueckert

Data-driven brain parcellations aim to provide a more accurate representation of an individual's functional connectivity, since they are able to capture individual variability that arises due to development or disease.

Graph Matching

Unsupervised domain adaptation in brain lesion segmentation with adversarial networks

1 code implementation28 Dec 2016 Konstantinos Kamnitsas, Christian Baumgartner, Christian Ledig, Virginia F. J. Newcombe, Joanna P. Simpson, Andrew D. Kane, David K. Menon, Aditya Nori, Antonio Criminisi, Daniel Rueckert, Ben Glocker

In this work we investigate unsupervised domain adaptation using adversarial neural networks to train a segmentation method which is more invariant to differences in the input data, and which does not require any annotations on the test domain.

Lesion Segmentation Segmentation +1

Comparison of Brain Networks with Unknown Correspondences

no code implementations15 Nov 2016 Sofia Ira Ktena, Sarah Parisot, Jonathan Passerat-Palmbach, Daniel Rueckert

In this work we explore a method based on graph edit distance for evaluating graph similarity, when correspondences between network elements are unknown due to different underlying subdivisions of the brain.

Graph Similarity

Recurrent neural networks for aortic image sequence segmentation with sparse annotations

no code implementations1 Aug 2018 Wenjia Bai, Hideaki Suzuki, Chen Qin, Giacomo Tarroni, Ozan Oktay, Paul M. Matthews, Daniel Rueckert

In this work, we propose an image sequence segmentation algorithm by combining a fully convolutional network with a recurrent neural network, which incorporates both spatial and temporal information into the segmentation task.

Anatomy Segmentation

Deep Learning using K-space Based Data Augmentation for Automated Cardiac MR Motion Artefact Detection

no code implementations15 Aug 2018 Ilkay Oksuz, Bram Ruijsink, Esther Puyol-Anton, Aurelien Bustin, Gastao Cruz, Claudia Prieto, Daniel Rueckert, Julia A. Schnabel, Andrew P. King

As this is a highly imbalanced classification problem (due to the high number of good quality images compared to the low number of images with motion artefacts), we propose a novel k-space based training data augmentation approach in order to address this problem.

Data Augmentation Image Quality Assessment +1

A Comprehensive Approach for Learning-based Fully-Automated Inter-slice Motion Correction for Short-Axis Cine Cardiac MR Image Stacks

no code implementations3 Oct 2018 Giacomo Tarroni, Ozan Oktay, Matthew Sinclair, Wenjia Bai, Andreas Schuh, Hideaki Suzuki, Antonio de Marvao, Declan O'Regan, Stuart Cook, Daniel Rueckert

If long axis (LA) images are available, PSMs are generated for them and combined to create the target PSM; if not, the target PSM is produced from the same stack using a 3D model trained from motion-free stacks.

Motion Compensation

Automatic CNN-based detection of cardiac MR motion artefacts using k-space data augmentation and curriculum learning

no code implementations29 Oct 2018 Ilkay Oksuz, Bram Ruijsink, Esther Puyol-Anton, James Clough, Gastao Cruz, Aurelien Bustin, Claudia Prieto, Rene Botnar, Daniel Rueckert, Julia A. Schnabel, Andrew P. King

Due to the high number of good quality images compared to the relatively low number of images with motion artefacts, we propose a novel data augmentation scheme based on synthetic artefact creation in k-space.

Data Augmentation General Classification +2

GANsfer Learning: Combining labelled and unlabelled data for GAN based data augmentation

no code implementations26 Nov 2018 Christopher Bowles, Roger Gunn, Alexander Hammers, Daniel Rueckert

We also show how a shift in domain of the training data from young and healthy towards older and more pathological examples leads to better segmentations of the latter cases, and that this leads to a significant improvement in the ability for the computed segmentations to stratify cases of AD.

Data Augmentation Segmentation

Computational Anatomy for Multi-Organ Analysis in Medical Imaging: A Review

no code implementations20 Dec 2018 Juan J. Cerrolaza, Mirella Lopez-Picazo, Ludovic Humbert, Yoshinobu Sato, Daniel Rueckert, Miguel Angel Gonzalez Ballester, Marius George Linguraru

With more than 300 papers included in this review, we reflect on the trends and challenges of the field of computational anatomy, the particularities of each anatomical region, and the potential of multi-organ analysis to increase the impact of 35 medical imaging applications on the future of healthcare.

Anatomy

Patch-based Evaluation of Image Segmentation

no code implementations CVPR 2014 Christian Ledig, Wenzhe Shi, Wenjia Bai, Daniel Rueckert

The ideal similarity measure should be unbiased to segmentations of different volume and complexity, and be able to quantify and visualise segmentation bias.

Hippocampus Image Segmentation +2

Unsupervised Deformable Registration for Multi-Modal Images via Disentangled Representations

no code implementations22 Mar 2019 Chen Qin, Bibo Shi, Rui Liao, Tommaso Mansi, Daniel Rueckert, Ali Kamen

The proposed registration approach is then built on the factorized latent shape code, with the assumption that the intrinsic shape deformation existing in original image domain is preserved in this latent space.

Image Registration Image-to-Image Translation

Meta-Weighted Gaussian Process Experts for Personalized Forecasting of AD Cognitive Changes

no code implementations19 Apr 2019 Ognjen Rudovic, Yuria Utsumi, Ricardo Guerrero, Kelly Peterson, Daniel Rueckert, Rosalind W. Picard

We introduce a novel personalized Gaussian Process Experts (pGPE) model for predicting per-subject ADAS-Cog13 cognitive scores -- a significant predictor of Alzheimer's Disease (AD) in the cognitive domain -- over the future 6, 12, 18, and 24 months.

Meta-Learning regression

Explainable Anatomical Shape Analysis through Deep Hierarchical Generative Models

1 code implementation28 Jun 2019 Carlo Biffi, Juan J. Cerrolaza, Giacomo Tarroni, Wenjia Bai, Antonio de Marvao, Ozan Oktay, Christian Ledig, Loic Le Folgoc, Konstantinos Kamnitsas, Georgia Doumou, Jinming Duan, Sanjay K. Prasad, Stuart A. Cook, Declan P. O'Regan, Daniel Rueckert

At the highest level of this hierarchy, a two-dimensional latent space is simultaneously optimised to discriminate distinct clinical conditions, enabling the direct visualisation of the classification space.

Anatomy

Data Efficient Unsupervised Domain Adaptation for Cross-Modality Image Segmentation

no code implementations5 Jul 2019 Cheng Ouyang, Konstantinos Kamnitsas, Carlo Biffi, Jinming Duan, Daniel Rueckert

Deep unsupervised domain adaptation (UDA) aims to improve the performance of a deep neural network model on a target domain, using solely unlabelled target domain data and labelled source domain data.

Image Segmentation Medical Image Segmentation +3

Self-Supervised Learning for Cardiac MR Image Segmentation by Anatomical Position Prediction

no code implementations5 Jul 2019 Wenjia Bai, Chen Chen, Giacomo Tarroni, Jinming Duan, Florian Guitton, Steffen E. Petersen, Yike Guo, Paul M. Matthews, Daniel Rueckert

In the recent years, convolutional neural networks have transformed the field of medical image analysis due to their capacity to learn discriminative image features for a variety of classification and regression tasks.

Image Segmentation Position +4

Assessing the Impact of Blood Pressure on Cardiac Function Using Interpretable Biomarkers and Variational Autoencoders

no code implementations13 Aug 2019 Esther Puyol-Antón, Bram Ruijsink, James R. Clough, Ilkay Oksuz, Daniel Rueckert, Reza Razavi, Andrew P. King

Maintaining good cardiac function for as long as possible is a major concern for healthcare systems worldwide and there is much interest in learning more about the impact of different risk factors on cardiac health.

Unsupervised Multi-modal Style Transfer for Cardiac MR Segmentation

no code implementations20 Aug 2019 Chen Chen, Cheng Ouyang, Giacomo Tarroni, Jo Schlemper, Huaqi Qiu, Wenjia Bai, Daniel Rueckert

In this work, we present a fully automatic method to segment cardiac structures from late-gadolinium enhanced (LGE) images without using labelled LGE data for training, but instead by transferring the anatomical knowledge and features learned on annotated balanced steady-state free precession (bSSFP) images, which are easier to acquire.

Image Segmentation Segmentation +3

Joint Motion Estimation and Segmentation from Undersampled Cardiac MR Image

no code implementations20 Aug 2019 Chen Qin, Wenjia Bai, Jo Schlemper, Steffen E. Petersen, Stefan K. Piechnik, Stefan Neubauer, Daniel Rueckert

Accelerating the acquisition of magnetic resonance imaging (MRI) is a challenging problem, and many works have been proposed to reconstruct images from undersampled k-space data.

Image Reconstruction Motion Estimation +1

Flexible Conditional Image Generation of Missing Data with Learned Mental Maps

no code implementations29 Aug 2019 Benjamin Hou, Athanasios Vlontzos, Amir Alansary, Daniel Rueckert, Bernhard Kainz

Real-world settings often do not allow acquisition of high-resolution volumetric images for accurate morphological assessment and diagnostic.

Anatomy Conditional Image Generation +2

Model-Based and Data-Driven Strategies in Medical Image Computing

no code implementations23 Sep 2019 Daniel Rueckert, Julia A. Schnabel

With the availability of large amounts of imaging data and machine learning (in particular deep learning) techniques, data-driven approaches have become more widespread for use in different tasks in reconstruction, analysis and interpretation.

Image Reconstruction Transfer Learning

Intelligent image synthesis to attack a segmentation CNN using adversarial learning

no code implementations24 Sep 2019 Liang Chen, Paul Bentley, Kensaku MORI, Kazunari Misawa, Michitaka Fujiwara, Daniel Rueckert

Our approach has three key features: 1) The generated adversarial examples exhibit anatomical variations (in form of deformations) as well as appearance perturbations; 2) The adversarial examples attack segmentation models so that the Dice scores decrease by a pre-specified amount; 3) The attack is not required to be specified beforehand.

Image Generation Image Segmentation +3

Joint analysis of clinical risk factors and 4D cardiac motion for survival prediction using a hybrid deep learning network

no code implementations7 Oct 2019 Shihao Jin, Nicolò Savioli, Antonio de Marvao, Timothy JW Dawes, Axel Gandy, Daniel Rueckert, Declan P. O'Regan

In this work, a novel approach is proposed for joint analysis of high dimensional time-resolved cardiac motion features obtained from segmented cardiac MRI and low dimensional clinical risk factors to improve survival prediction in heart failure.

Survival Prediction

Regression Forest-Based Atlas Localization and Direction Specific Atlas Generation for Pancreas Segmentation

no code implementations7 May 2020 Masahiro Oda, Natsuki Shimizu, Ken'ichi Karasawa, Yukitaka Nimura, Takayuki Kitasaka, Kazunari Misawa, Michitaka Fujiwara, Daniel Rueckert, Kensaku MORI

This paper proposes a fully automated atlas-based pancreas segmentation method from CT volumes utilizing atlas localization by regression forest and atlas generation using blood vessel information.

Automated Pancreas Segmentation Pancreas Segmentation +3

3D Probabilistic Segmentation and Volumetry from 2D projection images

no code implementations23 Jun 2020 Athanasios Vlontzos, Samuel Budd, Benjamin Hou, Daniel Rueckert, Bernhard Kainz

X-Ray imaging is quick, cheap and useful for front-line care assessment and intra-operative real-time imaging (e. g., C-Arm Fluoroscopy).

Deep Generative Model-based Quality Control for Cardiac MRI Segmentation

no code implementations23 Jun 2020 Shuo Wang, Giacomo Tarroni, Chen Qin, Yuanhan Mo, Chengliang Dai, Chen Chen, Ben Glocker, Yike Guo, Daniel Rueckert, Wenjia Bai

Our approach provides a real-time and model-agnostic quality control for cardiac MRI segmentation, which has the potential to be integrated into clinical image analysis workflows.

Image Segmentation MRI segmentation +2

A review of deep learning in medical imaging: Imaging traits, technology trends, case studies with progress highlights, and future promises

no code implementations2 Aug 2020 S. Kevin Zhou, Hayit Greenspan, Christos Davatzikos, James S. Duncan, Bram van Ginneken, Anant Madabhushi, Jerry L. Prince, Daniel Rueckert, Ronald M. Summers

In this survey paper, we first present traits of medical imaging, highlight both clinical needs and technical challenges in medical imaging, and describe how emerging trends in deep learning are addressing these issues.

Uncertainty Quantification

Causal Future Prediction in a Minkowski Space-Time

no code implementations20 Aug 2020 Athanasios Vlontzos, Henrique Bergallo Rocha, Daniel Rueckert, Bernhard Kainz

In this paper we propose a novel theoretical framework to perform causal future prediction by embedding spatiotemporal information on a Minkowski space-time.

Future prediction Image Generation

Patch-based Brain Age Estimation from MR Images

no code implementations29 Aug 2020 Kyriaki-Margarita Bintsi, Vasileios Baltatzis, Arinbjörn Kolbeinsson, Alexander Hammers, Daniel Rueckert

Many studies have been proposed for the prediction of chronological age from brain MRI using machine learning and specifically deep learning techniques.

Age Estimation Hippocampus

Mutual Information-based Disentangled Neural Networks for Classifying Unseen Categories in Different Domains: Application to Fetal Ultrasound Imaging

no code implementations30 Oct 2020 Qingjie Meng, Jacqueline Matthew, Veronika A. Zimmer, Alberto Gomez, David F. A. Lloyd, Daniel Rueckert, Bernhard Kainz

To address this problem, we propose Mutual Information-based Disentangled Neural Networks (MIDNet), which extract generalizable categorical features to transfer knowledge to unseen categories in a target domain.

Image Classification

A Systematic Comparison of Encrypted Machine Learning Solutions for Image Classification

no code implementations10 Nov 2020 Veneta Haralampieva, Daniel Rueckert, Jonathan Passerat-Palmbach

This work provides a comprehensive review of existing frameworks based on secure computing techniques in the context of private image classification.

BIG-bench Machine Learning General Classification +2

2CP: Decentralized Protocols to Transparently Evaluate Contributivity in Blockchain Federated Learning Environments

no code implementations15 Nov 2020 Harry Cai, Daniel Rueckert, Jonathan Passerat-Palmbach

While the initial model might belong solely to the actor bringing it to the network for training, determining the ownership of the trained model resulting from Federated Learning remains an open question.

Federated Learning Model Poisoning +1

Reducing Textural Bias Improves Robustness of Deep Segmentation Models

no code implementations30 Nov 2020 Seoin Chai, Daniel Rueckert, Ahmed E. Fetit

In this thorough empirical study, we draw inspiration from findings on natural images and investigate ways in which addressing the textural bias phenomenon could bring up the robustness of deep segmentation models when applied to three-dimensional (3D) medical data.

Image Classification Segmentation +1

Robust Aggregation for Adaptive Privacy Preserving Federated Learning in Healthcare

no code implementations17 Sep 2020 Matei Grama, Maria Musat, Luis Muñoz-González, Jonathan Passerat-Palmbach, Daniel Rueckert, Amir Alansary

In this work, we implement and evaluate different robust aggregation methods in FL applied to healthcare data.

Cryptography and Security

FedDis: Disentangled Federated Learning for Unsupervised Brain Pathology Segmentation

no code implementations5 Mar 2021 Cosmin I. Bercea, Benedikt Wiestler, Daniel Rueckert, Shadi Albarqouni

Further, we illustrate that FedDis learns a shape embedding that is orthogonal to the appearance and consistent under different intensity augmentations.

Anatomy Anomaly Detection +3

Automated Knee X-ray Report Generation

no code implementations22 May 2021 Aydan Gasimova, Giovanni Montana, Daniel Rueckert

Gathering manually annotated images for the purpose of training a predictive model is far more challenging in the medical domain than for natural images as it requires the expertise of qualified radiologists.

Text Generation

Learning a Model-Driven Variational Network for Deformable Image Registration

no code implementations25 May 2021 Xi Jia, Alexander Thorley, Wei Chen, Huaqi Qiu, Linlin Shen, Iain B Styles, Hyung Jin Chang, Ales Leonardis, Antonio de Marvao, Declan P. O'Regan, Daniel Rueckert, Jinming Duan

We then propose two neural layers (i. e. warping layer and intensity consistency layer) to model the analytical solution and a residual U-Net to formulate the denoising problem (i. e. generalized denoising layer).

Denoising Image Registration

Video Summarization through Reinforcement Learning with a 3D Spatio-Temporal U-Net

no code implementations19 Jun 2021 Tianrui Liu, Qingjie Meng, Jun-Jie Huang, Athanasios Vlontzos, Daniel Rueckert, Bernhard Kainz

Intelligent video summarization algorithms allow to quickly convey the most relevant information in videos through the identification of the most essential and explanatory content while removing redundant video frames.

reinforcement-learning Reinforcement Learning (RL) +1

Joint Motion Correction and Super Resolution for Cardiac Segmentation via Latent Optimisation

no code implementations8 Jul 2021 Shuo Wang, Chen Qin, Nicolo Savioli, Chen Chen, Declan O'Regan, Stuart Cook, Yike Guo, Daniel Rueckert, Wenjia Bai

In cardiac magnetic resonance (CMR) imaging, a 3D high-resolution segmentation of the heart is essential for detailed description of its anatomical structures.

Anatomy Cardiac Segmentation +2

Sensitivity analysis in differentially private machine learning using hybrid automatic differentiation

no code implementations9 Jul 2021 Alexander Ziller, Dmitrii Usynin, Moritz Knolle, Kritika Prakash, Andrew Trask, Rickmer Braren, Marcus Makowski, Daniel Rueckert, Georgios Kaissis

Reconciling large-scale ML with the closed-form reasoning required for the principled analysis of individual privacy loss requires the introduction of new tools for automatic sensitivity analysis and for tracking an individual's data and their features through the flow of computation.

BIG-bench Machine Learning

NeuralDP Differentially private neural networks by design

no code implementations30 Jul 2021 Moritz Knolle, Dmitrii Usynin, Alexander Ziller, Marcus R. Makowski, Daniel Rueckert, Georgios Kaissis

The application of differential privacy to the training of deep neural networks holds the promise of allowing large-scale (decentralized) use of sensitive data while providing rigorous privacy guarantees to the individual.

Partial sensitivity analysis in differential privacy

1 code implementation22 Sep 2021 Tamara T. Mueller, Alexander Ziller, Dmitrii Usynin, Moritz Knolle, Friederike Jungmann, Daniel Rueckert, Georgios Kaissis

However, while techniques such as individual R\'enyi DP (RDP) allow for granular, per-person privacy accounting, few works have investigated the impact of each input feature on the individual's privacy loss.

Image Classification

An automatic differentiation system for the age of differential privacy

no code implementations22 Sep 2021 Dmitrii Usynin, Alexander Ziller, Moritz Knolle, Andrew Trask, Kritika Prakash, Daniel Rueckert, Georgios Kaissis

We introduce Tritium, an automatic differentiation-based sensitivity analysis framework for differentially private (DP) machine learning (ML).

BIG-bench Machine Learning

A unified interpretation of the Gaussian mechanism for differential privacy through the sensitivity index

no code implementations22 Sep 2021 Georgios Kaissis, Moritz Knolle, Friederike Jungmann, Alexander Ziller, Dmitrii Usynin, Daniel Rueckert

$\psi$ uniquely characterises the GM and its properties by encapsulating its two fundamental quantities: the sensitivity of the query and the magnitude of the noise perturbation.

DeepMCAT: Large-Scale Deep Clustering for Medical Image Categorization

no code implementations30 Sep 2021 Turkay Kart, Wenjia Bai, Ben Glocker, Daniel Rueckert

In recent years, the research landscape of machine learning in medical imaging has changed drastically from supervised to semi-, weakly- or unsupervised methods.

Clustering Deep Clustering +1

FedRAD: Federated Robust Adaptive Distillation

no code implementations2 Dec 2021 Stefán Páll Sturluson, Samuel Trew, Luis Muñoz-González, Matei Grama, Jonathan Passerat-Palmbach, Daniel Rueckert, Amir Alansary

The robustness of federated learning (FL) is vital for the distributed training of an accurate global model that is shared among large number of clients.

Federated Learning Knowledge Distillation +1

AI-based Reconstruction for Fast MRI -- A Systematic Review and Meta-analysis

no code implementations23 Dec 2021 Yutong Chen, Carola-Bibiane Schönlieb, Pietro Liò, Tim Leiner, Pier Luigi Dragotti, Ge Wang, Daniel Rueckert, David Firmin, Guang Yang

Compressed sensing (CS) has been playing a key role in accelerating the magnetic resonance imaging (MRI) acquisition process.

Distributed Machine Learning and the Semblance of Trust

no code implementations21 Dec 2021 Dmitrii Usynin, Alexander Ziller, Daniel Rueckert, Jonathan Passerat-Palmbach, Georgios Kaissis

The utilisation of large and diverse datasets for machine learning (ML) at scale is required to promote scientific insight into many meaningful problems.

BIG-bench Machine Learning Federated Learning +1

Multi-modal unsupervised brain image registration using edge maps

no code implementations9 Feb 2022 Vasiliki Sideri-Lampretsa, Georgios Kaissis, Daniel Rueckert

Diffeomorphic deformable multi-modal image registration is a challenging task which aims to bring images acquired by different modalities to the same coordinate space and at the same time to preserve the topology and the invertibility of the transformation.

Image Registration

Beyond Gradients: Exploiting Adversarial Priors in Model Inversion Attacks

no code implementations1 Mar 2022 Dmitrii Usynin, Daniel Rueckert, Georgios Kaissis

Collaborative machine learning settings like federated learning can be susceptible to adversarial interference and attacks.

Federated Learning

Differentially private training of residual networks with scale normalisation

no code implementations1 Mar 2022 Helena Klause, Alexander Ziller, Daniel Rueckert, Kerstin Hammernik, Georgios Kaissis

The training of neural networks with Differentially Private Stochastic Gradient Descent offers formal Differential Privacy guarantees but introduces accuracy trade-offs.

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